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The global spread of viral diseases is a public health issue. Ribavirin (RBV) and mycophenolic acid (MPA) are well-known wide-spectrum antiviral agents.
Mayra A. Castañeda Cataña +7 more
doaj +1 more source
The family Arenaviridae, genus Arenavirus, consists of two phylogenetically independent groups: Old World (OW) and New World (NW) complexes. The Lassa and Lujo viruses in the OW complex and the Guanarito, Junin, Machupo, Sabia, and Chapare viruses in the
Masayuki Saijo +4 more
doaj +1 more source
Modulation of the Aryl Hydrocarbon Receptor Signaling Pathway Impacts on Junín Virus Replication. [PDF]
Pelaez MA +6 more
europepmc +1 more source
Potential and action mechanism of favipiravir as an antiviral against Junin virus. [PDF]
Zadeh VR +4 more
europepmc +1 more source
Inhibitors of the p38 cell signaling pathway as antiviral compounds against Junín virus. [PDF]
Brunetti JE +3 more
europepmc +1 more source
A review of emerging health threats from zoonotic New World mammarenaviruses
Despite repeated spillover transmission and their potential to cause significant morbidity and mortality in human hosts, the New World mammarenaviruses remain largely understudied.
Arianna Lendino +3 more
doaj +1 more source
Second-Generation Live-Attenuated Candid#1 Vaccine Virus Resists Reversion and Protects against Lethal Junín Virus Infection in Guinea Pigs. [PDF]
Gowen BB +7 more
europepmc +1 more source
Cellular N-Myristoyl Transferases Are Required for Mammarenavirus Multiplication
The mammarenavirus matrix Z protein plays critical roles in virus assembly and cell egress. Meanwhile, heterotrimer complexes of a stable signal peptide (SSP) together with glycoprotein subunits GP1 and GP2, generated via co-and post-translational ...
Haydar Witwit +8 more
doaj +1 more source

