Results 1 to 10 of about 1,703 (147)

Epidemiology of Machupo Virus Infection

American Journal of Tropical Medicine and Hygiene, 1965
Summary The localities in Bolivia from which cases of hemorrhagic fever have been reported are farming communities with characteristic ecological features. The rodent, Calomys callosus, is an important reservoir host of the Machupo virus. An experimental program of disease control was successfully carried out in San Joaquin, Beni, Bolivia.
Rita De Cássia Ribeiro Silva, Ana Marlúcia Oliveira Assis   +1 more
exaly   +10 more sources

Chronic Infection of Rodents by Machupo Virus

Science, 1965
Machupo virus, the etiologic agent of human hemorrhagic fever in Bolivia, induced chronic asymptomatic infection in laboratory hamsters and colonized individuals of the peridomestic, wild, South American rodent, Calomys callosus . Viruria was detected for more than 500 and 150 days, respectively, in the two species.
R B Mackenzie, P A Webb
exaly   +3 more sources

Properties of Machupo Virus

American Journal of Tropical Medicine and Hygiene, 1965
Comment and Summary The infant hamster appears to be the most sensitive host system thus far devised for detection of naturally occurring strains of Machupo virus. Infected brains also serve as a convenient source of CF antigens which can be employed for provisional grouping of hamster pathogenic isolates.
P A Webb, H Nalwoga
exaly   +3 more sources

Immune Tolerance in Calomys callosus infected with Machupo Virus

Nature, 1969
MACHUPO virus, the aetiological agent of Bolivian haemorrhagic fever, is an ether-sensitive RNA virus immunologically classified as a member of the Tacaribe group of “arboviruses”1–3. Repeated isolation of this virus from the cricetine rodent Calomys callosus4, the demonstration of chronic virus infection with persistent viruria in this animal5, and ...
Karl M Johnson, Johnson Karl M
exaly   +3 more sources

Machupo virus polypeptides: Identification by immunoprecipitation

Archives of Virology, 1985
The most abundant protein in purified Machupo virions (Corvallo strain) labelled with 14C-Protein hydrolysate is a 64 K polypeptide which is associated with virion RNAs. Another structural polypeptide, 37 K, solubilized by nonionic detergent seems to be a major surface glycoprotein.
I S Lukashevich, Lukashevich I S
exaly   +3 more sources

Isolation of Machupo Virus from Wild Rodent Calomys callosus

American Journal of Tropical Medicine and Hygiene, 1966
Summary Nine virus strains were recovered from a small group of tissues from the wild rodent Calomys callosus captured in the area of San Joaquin, Bolivia, in 1963. Each virus was successfully reisolated and shown to be serologically related to Machupo virus, the etiologic agent of Bolivian Hemorrhagic Fever.
P A Webb, R B Mackenzie, C E Yunker
exaly   +3 more sources

Some Characteristics of Machupo Virus, Causative Agent of Bolivian Hemorrhagic Fever

American Journal of Tropical Medicine and Hygiene, 1967
Summary Certain properties of Machupo virus are reported. These include presence of RNA, pH stability in the range of 6.0 to 9.0, rapid thermal inactivation at temperatures of 25°C and higher, and more effective stabilization of infectivity titers after prolonged storage (1 year) at -70°C in media containing protein supplements.
P A Webb, R B Mackenzie
exaly   +3 more sources

The African Green Monkey as an Alternate Primate Host for Studying Machupo Virus Infection

American Journal of Tropical Medicine and Hygiene, 1977
African green monkeys (Cercopithecus aethiops) are highly susceptible to Bolivian hemorrhagic fever (BHF). Six monkeys were inoculated with 1,000 plague-forming units of Machupo virus, the etiologic agent of BHF. They were observed and monitored for clinical signs, body temperature, viremia, hematologic changes, and virus neutralizing antibody.
Gerald A Eddy
exaly   +3 more sources

Organisms of Concern but not Foodborne or Confirmed Foodborne: Bolivian Hemorrhagic Fever Virus (Machupo Virus)

2014
D M Castañeda-Hernández
exaly   +2 more sources