Results 121 to 130 of about 5,614 (215)

Innate and adaptive immune control of genetically engineered live-attenuated arenavirus vaccine prototypes [PDF]

, 2017
Arenaviruses such as Lassa virus (LASV) cause significant morbidity and mortality in endemic areas. Using a glycoprotein (GP) exchange strategy, we have recently developed live-attenuated arenavirus vaccine prototypes (rLCMV/VSVG) based on lymphocytic ...
Bergthaler, Andreas, Fernandez, Marylise, Flatz, Lukas, Horvath, Edit, Lutz, Hans, Pinschewer, Daniel D., Steinborn, Ralf, Suter, Mark   +7 more
core  

Cellular N-Myristoyl Transferases Are Required for Mammarenavirus Multiplication

Viruses
The mammarenavirus matrix Z protein plays critical roles in virus assembly and cell egress. Meanwhile, heterotrimer complexes of a stable signal peptide (SSP) together with glycoprotein subunits GP1 and GP2, generated via co-and post-translational ...
Haydar Witwit, Carlos Alberto Betancourt, Beatrice Cubitt, Roaa Khafaji, Heinrich Kowalski, Nathaniel Jackson, Chengjin Ye, Luis Martinez-Sobrido, Juan C. de la Torre   +8 more
doaj   +1 more source

Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects [PDF]

, 2017
Diamond, Michael S, et al,, Govero, Jennifer   +2 more
core   +2 more sources

Development of horse neutralizing immunoglobulin and immunoglobulin fragments against Junín virus. [PDF]

Antiviral Res, 2020
Pan X, Wu Y, Wang W, Zhang L, Xiao G.
europepmc   +1 more source

Development of a Reverse Genetic System to Generate Recombinant Chimeric Tacaribe Virus that Expresses Junín Virus Glycoproteins. [PDF]

Pathogens, 2020
Foscaldi S, Loureiro ME, Sepúlveda C, Palacios C, Forlenza MB, López N.   +5 more
europepmc   +1 more source

[Inhibition of Junin virus multiplication by caffeine].

Revista Argentina de microbiologia, 1999
The inhibitory activity of caffeine, a pharmacologically active compound, on Junin virus (JV) multiplication in Vero cells was evaluated by a virus yield inhibition assay. The compound achieved a dose-dependent inhibition of virus production at concentrations not affecting cell viability.
N A, Candurra, E B, Damonte
openaire   +1 more source

Los nuevos escenarios de transmisión de la fiebre hemorrágica Argentina desde la introducción de la vacuna a virus junín vivo atenuado (Candid#1): una experiencia en trabajadores golondrinas

Revista Peruana de Medicina Experimental y Salud Pública
La fiebre hemorrágica Argentina (FHA) es una enfermedad viral aguda grave causada por el virus Junín, de la familia Arenaviridae. El área endémica de la FHA coincide geográficamente con el mayor complejo agroindustrial cerealero de exportación del ...
Ana Briggiler, Anabel Sinchi, Florencia Coronel, Zaida Sánchez, Silvana Levis, Jorge Taylor, Delia Enria   +6 more
doaj   +2 more sources

Guinea Pig Transferrin Receptor 1 Mediates Cellular Entry of Junín Virus and Other Pathogenic New World Arenaviruses. [PDF]

J Virol, 2020
Hickerson BT, Westover JB, Wang Z, Lee YM, Gowen BB.   +4 more
europepmc   +1 more source

The Glycoprotein of the Live-Attenuated Junin Virus Vaccine Strain Induces Endoplasmic Reticulum Stress and Forms Aggregates prior to Degradation in the Lysosome. [PDF]

J Virol, 2020
Manning JT, Yun NE, Seregin AV, Koma T, Sattler RA, Ezeomah C, Huang C, de la Torre JC, Paessler S.   +8 more
europepmc   +1 more source

Climate Change Impact on Human-Rodent Interfaces: Modeling Junin Virus Reservoir Shifts. [PDF]

Ecohealth
Flores-Pérez N, Kulkarni P, Uhart M, Pandit PS.   +3 more
europepmc   +1 more source