Results 61 to 70 of about 43,474 (209)
PLoS ONE, 2010 BackgroundThe chemokine CXCL12/SDF-1alpha interacts with its G-protein coupled receptor CXCR4 to induce migration of lymphoid and endothelial cells. T cell specific adapter protein (TSAd) has been found to promote migration of Jurkat T cells through ...
Tone Berge +8 more
doaj +1 more source
Advanced Science, EarlyView.MM‐NPs@PLK1 are formed by encapsulating PLK1 plasmids within CBP5 and coating the nanocomplexes with macrophage membranes. After macrophage‐associated uptake, the NPs@PLK1 enter the cytoplasm and release the PLK1‐encoding plasmid in response to elevated intracellular ROS levels.
Zhenxin Hu +13 more
wiley +1 more source
Plasma Membrane Lipid Asymmetry Dynamically Regulates Passive Diffusion
Advanced Science, EarlyView.Passive diffusion enables hydrophobic molecules to cross the plasma membrane and exert their biological functions. This study demonstrates that plasma membrane lipid asymmetry, dynamically regulated by lipid scrambling, determines membrane permeability to lipophilic molecules and thereby modulates their cellular activities.
Jieming Ping +4 more
wiley +1 more source
Exosomes are unlikely involved in intercellular Nef transfer. [PDF]
PLoS ONE, 2015 HIV-1 Nef is an important pathogenic factor for HIV/AIDS pathogenesis. Several recent studies including ours have demonstrated that Nef can be transferred to neighboring cells and alters the function of these cells.
Xiaoyu Luo +3 more
doaj +1 more source
Advanced Science, EarlyView.MG‐1 is a bifunctional small molecule that enhances the removal of damaged mitochondria through autophagy, the cell's recycling pathway. Its activity increases under mitochondrial stress, with minimal effects on basal autophagy. MG‐1 also improves movement in a zebrafish model of mitochondrial dysfunction, supporting further investigation of this ...
Ratislav M. Ozhiganov +24 more
wiley +1 more source
CD3 receptor modulation in Jurkat leukemic cell line.
Folia Histochemica et Cytobiologica, 2004 CD3 antigen is a crucial molecule in T cell signal transduction. Although its expression on cell surface is constitutive, dynamic regulation of TCR-CD3 level is probably the most important mechanism allowing T cells to calibrate their response to ...
Jacek M Witkowski +3 more
doaj +1 more source
An EP receptor with a novel pharmacological profile in the T‐cell line Jurkat [PDF]
British Journal of Pharmacology, 1995 1. Comparison of the rank order of potency of the natural prostanoids prostaglandin E2 (PGE2), PGD2, PGF2 alpha and carbaprostacyclin in stimulating cyclic AMP in Jurkat cells is consistent with the presence of an EP receptor. 2. Lack of responsiveness to the EP1/EP3 selective agonist, sulprostone, and the EP2 agonists, butaprost and AH 13205 ...
G W, De Vries +5 more
openaire +2 more sources
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.Quantitative phase maps of single cells recorded in flow cytometry modality feed a hierarchical architecture of machine learning models for the label‐free identification of subtypes of ovarian cancer. The employment of a priori clinical information improves the classification performance, thus emulating the clinical application of liquid biopsy during ...
Daniele Pirone +11 more
wiley +1 more source
IET NanodielectricsJurkat cells are immortalised lines of human T lymphocyte cells widely used in research to study leukaemia, signalling of T cells, and immune responses.
Most. Momtahina Bani +3 more
doaj +1 more source
Programable Acoustic Single‐Cell Manipulation With Model‐Free Machine Learning
Advanced Intelligent Systems, EarlyView.Closed‐loop control with ultrasound enables precise, noninvasive manipulation of individual cells inside a microfluidic device using a model‐free reinforcement learning‐inspired algorithm, achieving 2D control using a single piezoelectric transducer.
Alexander Edthofer +3 more
wiley +1 more source