Results 141 to 150 of about 2,708,099 (339)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

A socially just transition through the European Green Deal?

, 2020
Sebastiano Sabato, Boris Fronteddu
openalex   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Enabling a Rapid and Just Transition away from Coal in China. [PDF]

One Earth, 2020
He G, Lin J, Zhang Y, Zhang W, Larangeira G, Zhang C, Peng W, Liu M, Yang F.   +8 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

“Small Sacrifice for the Greater Good”: Decoding Just Transition in a Chinese Peripheral Region

Social Inclusion
The notion of just transition is important and debated in discussions about climate change and low‐carbon shifts. This study aims to refocus on just transition from a spatial perspective.
Xiaohui Hu, Wu Tang, Xuliang Zhang, Dongzheng Jie   +3 more
doaj   +1 more source

Towards a theory of just transition: A neo-Gramscian understanding of how to shift development pathways to zero poverty and zero carbon. [PDF]

Energy Res Soc Sci, 2020
Winkler H.
europepmc   +1 more source

Just Sustainability Transitions

Annual Review of Environment and Resources
Facing the world's ecological, economic, and social challenges requires us to connect the concepts of justice, sustainability, and transitions. Bridging and discussing heterogeneous fields, we argue that these concepts need to complement each other, and we present just sustainability transitions (JUSTRAs) to do so.
Avelino, Flor, Wijsman, Katinka, van Steenbergen, Frank, Jhagroe, Shivant, Wittmayer, Julia, Akerboom, Sanne, Bogner, Kristina, Jansen, Esther F., Frantzeskaki, Niki, Kalfagianni, Agni   +9 more
openaire   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source