Results 71 to 80 of about 29,569 (257)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
A Philosophical Critique of Warfare in the Contemporary Era: ethical justifications and competing theories [PDF]
Journal of Philosophical InvestigationsThis study aims to provide a comprehensive philosophical critique of warfare in the contemporary era, focusing on ethical justifications and competing theoretical frameworks.
Homa Rahmani
doaj +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Peacekeeping & Jus Post Bellum: Towards a Concept of Rules in Post-Conflict Situations [PDF]
Central European Journal of International & Security Studies, 2011 This article argues that post-conflict peacekeeping should be seen as highly valuable for further developing jus post bellum, since the UN is the main actor in contemporary post-conflict situations.
Ivar Scheers
doaj
Controvers of the theory of just war in the writings of philosophers and Christian theologians
Українське Pелігієзнавство, 2004 Just war theory has a long history, during which it changed its nature and its constituent components. Its purpose was to justify and limit the evil of war. The term just war is found in Aristotle in his work "Politics" and is used in describing the wars
K. Semchynskiy
doaj +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
The Russo-Ukrainian conflict and the ethics of war of Augustine and Aquinas
Ethic@: an International Journal for Moral PhilosophyThis article analyzes the justice of the Russo-Ukrainian War from the views of just war theorists Augustine and Aquinas. Augustine of Hippo, in his war ethics, believed that war is both a consequence of sin and a potential remedy.
Pedro Erik Carneiro
doaj +1 more source