Results 121 to 130 of about 54,427 (263)

Glucocorticoids—All-Rounders Tackling the Versatile Players of the Immune System [PDF]

open access: yes, 2019
Glucocorticoids regulate fundamental processes of the human body and control cellular functions such as cell metabolism, growth, differentiation, and apoptosis.
Agarwal   +268 more
core   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

open access: yesPeriodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer   +4 more
wiley   +1 more source

The future of Korean rheumatology

open access: yesJournal of Rheumatic Diseases
Systemic lupus erythematosus (SLE) is an autoimmune disorder that can affect various organs. Juvenile-onset SLE (jSLE) may be more severe than the adult-onset form, but the diagnosis and classification remain challenging due to the complex nature of the ...
Bon San Koo, Jae-Bum Jun
doaj   +1 more source

Sex Matters: Hormonal and Chromosomal Determinants of Autoimmunity and Anti‐Cancer Immunity Across the Lifespan

open access: yesImmunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos   +4 more
wiley   +1 more source

Geographical Clustering of Juvenile Onset Systemic Lupus Erythematosus within the Sultanate of Oman

open access: yesOman Medical Journal, 2013
Objective: While SLE is found worldwide, there is diversity in clinical presentation of the disease according to geographical variations. The aim of this study is to describe geographical distributions of childhood onset SLE within Oman to identify ...
Ibrahim Al-Zakwani   +3 more
doaj   +1 more source

Autoimmune gastrointestinal complications in patients with Systemic Lupus Erythematosus: case series and literature review [PDF]

open access: yes, 2016
The association of systemic lupus erythematosus (SLE) with gastrointestinal autoimmune diseases is rare, but has been described in the literature, mostly as case reports.
Agmon-Levin N   +101 more
core   +1 more source

The American Black Bear (Ursus americanus) as an Apex Predator: Investigating the Ecological Role of the World's Most Abundant Large Carnivore

open access: yesMammal Review, Volume 56, Issue 1, March 2026.
Black bears as apex predators. American black bears can (1) produce top‐down effects on ungulates equal to or exceeding those of typical apex predators and (2) modify the spatiotemporal behaviour of other carnivores, including pumas and coyotes. We argue that the term ‘apex predator’ is highly context dependent and not a species‐wide status.
John M. Nettles   +10 more
wiley   +1 more source

Association between academic performance and cognitive dysfunction in patients with juvenile systemic lupus erythematosus

open access: yesRevista Brasileira de Reumatologia, 2016
Objective To determine whether there is an association between the profile of cognitive dysfunction and academic outcomes in patients with juvenile systemic lupus erythematosus (JSLE).
Renan Bazuco Frittoli   +5 more
doaj   +1 more source

Reduced expressions of apoptosis-related proteins TRAIL, Bcl-2, and TNFR1 in NK cells of juvenile-onset systemic lupus erythematosus patients: relations with disease activity, nephritis, and neuropsychiatric involvement

open access: yesFrontiers in Immunology
Background Lupus pathogenesis is mainly ascribed to increased production and/or impaired clearance of dead cell debris. Although self-reactive T and B lymphocytes are critically linked to lupus development, neutrophils, monocytes, and natural killer (NK)
B. Liphaus   +5 more
semanticscholar   +1 more source

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