Results 171 to 180 of about 1,185,551 (209)

Low Disease Activity State in Juvenile-Onset Systemic Lupus Erythematosus

open access: yesLupus, 2021
Objectives To determine the rate of achieving The Lupus Low Disease Activity State (LLDAS) in children with systemic lupus erythematosus (SLE) for tracing pertinent treatment modalities. Methods A total of 122 juvenile-onset SLE (jSLE)
Semanur Ozdel   +2 more
exaly   +5 more sources

Neuropsychiatric Involvement in Juvenile-Onset Systemic Lupus Erythematosus: Data From the UK Juvenile-Onset Systemic Lupus Erythematosus Cohort Study [PDF]

open access: yesLupus, 2021
Introduction Juvenile-onset systemic lupus erythematosus (JSLE) is a rare autoimmune/inflammatory disease with significant morbidity and mortality. Neuropsychiatric (NP) involvement is a severe complication, encompassing a heterogeneous range of neurological and psychiatric manifestations.
Athimalaipet V Ramanan   +2 more
exaly   +7 more sources

Juvenile-Onset Systemic Lupus Erythematosus (jSLE) – Pathophysiological Concepts and Treatment Options [PDF]

open access: yesBest Practice and Research in Clinical Rheumatology, 2017
The systemic autoimmune/inflammatory condition systemic lupus erythematosus (SLE) manifests before the age of 16 years in 10-20% of all cases. Clinical courses are more severe, and organ complications are more common in patients with juvenile SLE. Varying gender distribution in different age groups and increasing severity with younger age and the ...
Christian M Hedrich   +2 more
exaly   +4 more sources

Outcome in juvenile onset systemic lupus erythematosus

Current Opinion in Rheumatology, 2005
Over the past 2 decades, there has been a marked improvement in survival among patients with juvenile-onset systemic lupus erythematosus. As a result of the increased life expectancy, children and adolescents with systemic lupus erythematosus are now faced with considerable morbidity resulting from sequelae of disease activity, side effects of ...
RAVELLI, ANGELO   +2 more
openaire   +3 more sources

Associated Factors to Serious Infections in a Large Cohort of Juvenile-Onset Systemic Lupus Erythematosus From Lupus Registry (RELESSER).

open access: yesSeminars in Arthritis and Rheumatism, 2020
To assess the incidence of serious infection (SI) and associated factors in a large juvenile-onset systemic lupus erythematosus (jSLE) retrospective cohort. All patients in the Spanish Rheumatology Society Lupus Registry (RELESSER) who meet ≥4 ACR-97 SLE
Vicenç Torrente-Segarra   +1 more
exaly   +2 more sources

Treatment Options for Juvenile-Onset Systemic Lupus Erythematosus

Pediatric Drugs, 2002
Systemic lupus erythematosus (SLE) is an inflammatory chronic disease characterized by the presence of activated helper T-cells that induce a B-cell response, resulting in the secretion of pathogenic autoantibodies and the formation of immune complexes.
Luis, Carreño   +3 more
openaire   +2 more sources

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