Results 191 to 200 of about 1,119,311 (215)

Ocular Manifestations in Children with Juvenile-Onset Systemic Lupus Erythematosus

Seminars in Ophthalmology, 2017
To study the ocular manifestations of juvenile systemic lupus erythematosus (JSLE), including the ocular side-effects of the systemic medications used.A descriptive cross-sectional study on 40 children diagnosed with JSLE was conducted. Ophthalmological and laboratory investigations as well as a calculation of the Systemic Lupus Disease Activity Index ...
Ghada, Gawdat, Dina, El-Fayoumi, Huda, Marzouk, Yomna, Farag   +3 more
openaire   +2 more sources

SAT0277 Neuropsychiatric Involvement in Juvenile-Onset Systemic Lupus

Annals of the Rheumatic Diseases, 2016
Background Neuropsychiatric involvement in systemic lupus erythematosus (NPSLE) includes the neurological syndromes of the central, peripheral or autonomic nervous systems and psychiatric disorders. Some studies suggests that juvenile systemic lupus erythematosus (jSLE) has a more serious course and a more frequent neuropsychiatric involvement than ...
R. Fonseca, F. Aguiar, M. Rodrigues, I. Brito   +3 more
openaire   +1 more source

THU0330 Damage in juvenile-onset systemic lupus erythematosus

Annals of the Rheumatic Diseases, 2012
Background Children and adolescents with juvenile-onset systemic lupus erythematosus (jSLE) face considerable morbidity due to sequelae of disease activity, comorbidities and adverse effects of treatment. In order to improve the management of these patients, it is essential to better understand the risk factors associated with the development of ...
P. Costa Reis, J. Isgro, S. Nativ, C. Yildirim-Toruner, A. Starr, L. Imundo, A. Eichenfield   +6 more
openaire   +1 more source

Multi-disciplinary care in juvenile-onset systemic lupus erythematosus

British Journal of School Nursing, 2012
Juvenile onset systemic lupus erythematosus (JSLE) is a chronic autoimmune disease that can affect any part of the body including skin, joints and organs and can be associated with significant morbidity and mortality. Multi-disciplinary care of children and young people with JSLE is essential, in close partnership with schools.
Michael William Beresford
exaly   +2 more sources

Analysis of serum IL-38 in juvenile-onset systemic lupus erythematosus

Modern Rheumatology, 2018
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with widespread immunologic abnormalities and multiple organ involvement [1].
Yusuke, Takeuchi, Tomoko, Seki, Norimoto, Kobayashi, Kenji, Sano, Tomonari, Shigemura, Hisashi, Shimojo, Kazuhiko, Matsumoto, Kazunaga, Agematsu   +7 more
openaire   +2 more sources

Validation of the systemic lupus erythematosus responder index for use in juvenile-onset systemic lupus erythematosus

Annals of the Rheumatic Diseases, 2014
This study tested the concurrent validity of the systemic lupus erythematosus responder index (SRI) in assessing improvement in juvenile-onset systemic lupus erythematosus (jSLE).The SRI considers changes in the SELENA-SLEDAI, BILAG and a 3-cm visual analogue scale of physician-rated disease activity (PGA) to determine patient improvement.
Mina R, Klein Gitelman MS, Nelson S, Eberhard BA, Higgins G, Singer NG, Onel K, Tucker L, O'Neil KM, Punaro M, Levy DM, Haines K, MARTINI, ALBERTO, Ruperto N, Lovell D, Brunner HI   +15 more
openaire   +4 more sources

Juvenile-onset systemic lupus erythematosus: how to diagnose and manage

Paediatrics and Child Health (United Kingdom), 2015
Abstract Systemic lupus erythematosus (SLE) is the prototypic autoimmune disorder, characterised by auto-antibody production against nuclear antigens. Juvenile-onset systemic lupus erythematosus (JSLE) is a more severe form than the adult-onset disease, with a more balanced gender ratio.
Louise Oni, Michael William Beresford
exaly   +2 more sources

Herpes Zoster in Juvenile-Onset Systemic Lupus Erythematosus

The Pediatric Infectious Disease Journal, 2006
Herpes zoster (HZ) is common in systemic lupus erythematosus (SLE) patients, but its clinical features and risk factors in juvenile-onset SLE have not been well described before.A retrospective review of the clinical course and infections in pediatric SLE patients managed in our institution from 1988-2004 was performed.
HokKung Ho, M, Lau, YL, Lee, PPW, Lee, TL, Wong, WHS   +4 more
openaire   +5 more sources

HLA-DRB1 antigens in Taiwanese patients with juvenile-onset systemic lupus erythematosus

Rheumatology International, 2001
This study was done to investigate the frequency of HLA-DRB1 antigens in juvenile-onset systemic lupus erythematosus (SLE) in the Taiwanese population.Thirty-four Taiwanese patients with juvenile onset SLE and 200 unrelated healthy controls were studied.
J L, Huang, C K, Shaw, A, Lee, T D, Lee, Y H, Chou, M L, Kuo   +5 more
openaire   +2 more sources

Renal biomarkers in Juvenile-onset systemic lupus erythematosus

2013
Background: Juvenile-onset Systemic Lupus Erythematosus (JSLE) is a rare, but severe, autoimmune condition with lupus nephritis (LN) occurring in up to 80% of patients and predisposing to an increased mortality. Aims/Objectives: As part of the UK JSLE Cohort Study this study aimed to identify whether standard and/or novel biomarkers are useful for ...
openaire   +1 more source