Breaking the storm: canakinumab as salvage therapy for refractory macrophage activation syndrome in pediatric systemic lupus erythematosus-a case report. [PDF]
Pediatr Rheumatol Online JSelvarajan T +4 more
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Low disease activity state in juvenile-onset systemic lupus erythematosus
Lupus, 2021 Objectives To determine the rate of achieving The Lupus Low Disease Activity State (LLDAS) in children with systemic lupus erythematosus (SLE) for tracing pertinent treatment modalities.
Semanur Ozdel +2 more
exaly +5 more sources
Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: Data from the UK Juvenile-onset systemic lupus erythematosus cohort study [PDF]
Lupus, 2021 Introduction Juvenile-onset systemic lupus erythematosus (JSLE) is a rare autoimmune/inflammatory disease with significant morbidity and mortality. Neuropsychiatric (NP) involvement is a severe complication, encompassing a heterogeneous range of neurological and psychiatric manifestations.
Athimalaipet Ramanan +2 more
exaly +6 more sources
Best Practice and Research in Clinical Rheumatology, 2017 The systemic autoimmune/inflammatory condition systemic lupus erythematosus (SLE) manifests before the age of 16 years in 10-20% of all cases. Clinical courses are more severe, and organ complications are more common in patients with juvenile SLE. Varying gender distribution in different age groups and increasing severity with younger age and the ...
Christian Hedrich +2 more
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Outcome in juvenile onset systemic lupus erythematosus
Current Opinion in Rheumatology, 2005Over the past 2 decades, there has been a marked improvement in survival among patients with juvenile-onset systemic lupus erythematosus. As a result of the increased life expectancy, children and adolescents with systemic lupus erythematosus are now faced with considerable morbidity resulting from sequelae of disease activity, side effects of ...
RAVELLI, ANGELO +2 more
openaire +3 more sources
Treatment Options for Juvenile-Onset Systemic Lupus Erythematosus
Pediatric Drugs, 2002Systemic lupus erythematosus (SLE) is an inflammatory chronic disease characterized by the presence of activated helper T-cells that induce a B-cell response, resulting in the secretion of pathogenic autoantibodies and the formation of immune complexes.
Luis, Carreño +3 more
openaire +2 more sources
Juvenile onset systemic lupus erythematosus: a possible role for vitamin D in disease status and bone health [PDF]
Lupus, 2012 Purpose: In juvenile onset systemic lupus erythematosus (JoSLE), evidence for the association between vitamin D status, lupus activity, and bone health is very limited and not conclusive.
Eloisa Bonfa, Rosa M R Pereira
exaly +2 more sources
Pulmonary hypertension in juvenile-onset systemic lupus erythematosus: a case series
Clinical and Experimental Rheumatology, 2022Systemic lupus erythematosus (SLE) is a rare multisystem autoimmune disorder with a variable clinical phenotype. Pulmonary hypertension (PHTN) is a recognised (and not uncommonly asymptomatic) complication of the condition with an associated poor prognosis in adults.
Platt, Caroline +7 more
openaire +3 more sources
Anti‐C1q Antibodies in Juvenile‐Onset Systemic Lupus Erythematosus
Annals of the New York Academy of Sciences, 2009The objective of this study was to evaluate the presence of anti‐C1q antibodies Hospital Israelita Albert Einstein Research Institute, São Paulo, Brazil in 67 juvenile systemic lupus erythematosus (JSLE) patients and 26 healthy controls and to assess the association of these antibodies with disease activity, nephritis, and presence of anti‐double ...
A A, Jesus +6 more
openaire +2 more sources