Results 21 to 30 of about 54,427 (263)

Involving young people in research investigating comorbidity associated with childhood-onset rheumatic disease: perspectives of a series of focus groups [PDF]

BMC Rheumatology
Background Childhood-onset rheumatic diseases, such as juvenile idiopathic arthritis, juvenile-onset lupus and juvenile dermatomyositis, appear to be associated with an increased risk of comorbidities in adulthood compared to the general population.
Sab Siddiq, Jenny Sammy Ainsworth, Clare E. Pain, Eve M.D. Smith, Sizheng Steven Zhao, David M. Hughes, Liza J. McCann   +6 more
doaj   +2 more sources

Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: Data from the UK Juvenile-onset systemic lupus erythematosus cohort study [PDF]

Lupus, 2021
Introduction Juvenile-onset systemic lupus erythematosus (JSLE) is a rare autoimmune/inflammatory disease with significant morbidity and mortality. Neuropsychiatric (NP) involvement is a severe complication, encompassing a heterogeneous range of neurological and psychiatric manifestations.
Giani, Teresa, Smith, Eve MD, Al-Abadi, Eslam, Armon, Kate, Bailey, Kathryn, Ciurtin, Coziana, Davidson, Joyce, Gardner-Medwin, Janet, Haslam, Kirsty, Hawley, Dan P, Leahy, Alice, Leone, Valentina, McErlane, Flora, Mewar, Devesh, Modgil, Gita, Moots, Robert, Pilkington, Clarissa, Pregnolato, Francesca, Ramanan, Athimalaipet V, Rangaraj, Satyapal, Riley, Phil, Sridhar, Arani, Wilkinson, Nick, Cimaz, Rolando, Beresford, Michael W, Hedrich, Christian M, Study, On Behalf Of The UK JSLE Cohort   +26 more
openaire   +6 more sources

Abstract 13 — Comparison of Clinical and Serological Features in Juvenile and Adult-Onset Systemic Lupus Erythematosus

Journal of Clinical Rheumatology and Immunology, 2023
Background Systemic lupus erythematosus (SLE) has varying clinical and serological features in juvenile and adult-onset disease groups, depending on the ethnicity. Objectives: To compare the disease characteristics of patients with adult-onset (ASLE) and
Babur Salim, Anum Khan, Haris Gul, Saba Samreen, Shahida Perveen   +4 more
doaj   +1 more source

The role of assessment of renal biopsy in electron microscopy in making a diagnosis of juvenile-onset systemic lupus erythematosus in a 16-year-old female patient with depression and proteinuria – case report

Central European Journal of Immunology, 2022
The course of juvenile-onset systemic lupus erythematosus may vary, from rapid multiorgan involvement to insidious development mimicking different medical conditions.
Tomasz Koszutski, Agnieszka Wiernik, Lidia Hyla-Klekot, Natalia Matysiak, Grażyna Kucharska   +4 more
doaj   +1 more source

Rituximab therapy for juvenile-onset systemic lupus erythematosus [PDF]

Pediatric Nephrology, 2007
Rituximab (RTX), an anti-CD20 monoclonal antibody, has been proposed for use in the therapy of systemic lupus erythematosus (SLE). We present the initial long-term experience of the safety and efficacy of rituximab for treatment of SLE in children.
Nwobi, Obioma, Abitbol, Carolyn L., Chandar, Jayanthi, Seeherunvong, Wacharee, Zilleruelo, Gastón   +4 more
openaire   +2 more sources

Investigating biomarkers of disease activity in juvenile-onset lupus nephritis [PDF]

Rheumatology, 2014
E. Smith, L. Watson, C. Jones, C. Pilkington, S. Marks, K. Tullus, M. Beresford   +6 more
semanticscholar   +2 more sources

Juvenile-onset multifocal osteonecrosis in systemic lupus erythematosus

Medicine, 2021
Abstract Rationale: Osteonecrosis (ON) is a devastating illness that leads to bone ischemia and potential joint destruction. Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease, with multi-system involvement which is closely associated with occurrence of ON.
Jin, Wenyuan, Yang, Xinghui, Lu, Meiping
openaire   +2 more sources

What Have We Learnt About the Treatment of Juvenile-Onset Systemic Lupus Erythematous Since Development of the SHARE Recommendations 2012?

Frontiers in Pediatrics, 2022
IntroductionJuvenile-onset systemic lupus erythematous (JSLE) is a rare multisystem autoimmune disorder. In 2012, the Single Hub and Access point for pediatric Rheumatology in Europe (SHARE) initiative developed recommendations for the diagnosis ...
Kathy L. Gallagher, Pallavi Patel, Michael W. Beresford, Michael W. Beresford, Eve Mary Dorothy Smith, Eve Mary Dorothy Smith   +5 more
doaj   +1 more source

An unusual presentation of juvenile lupus nephritis

Saudi Journal of Kidney Diseases and Transplantation, 2016
The incidence of juvenile lupus varies widely ranging between 4 and 250 per 100,000 population. Most common organ involvement in juvenile lupus is kidney. Neurological, cutaneous and hematological involvements are also involved.
Malleshwar Bottu, Manjusha Yadla, Srikanth Burri, Megha Uppin   +3 more
doaj   +1 more source

Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature [PDF]

, 2015
Macrophage activation syndrome (MAS) is a potentially fatal condition. It is a rare complication of several autoimmune disorders, including systemic lupus erythematosus (SLE) and systemic juvenile idiopathic arthritis (sJIA).
Didona, Dario, Feola, Aldo, Granata, Guido, Granata, Massimo, Stifano, Giuseppina   +4 more
core   +4 more sources