Diabetes/Metabolism Research and Reviews, Volume 42, Issue 1, January 2026.ABSTRACT Timely diagnosis of type 1 diabetes (T1D), especially in high‐risk populations, is crucial for preventing serious health complications. T1D is a chronic progressive autoimmune disease that has presymptomatic stages that can be identified through the detection of islet autoantibodies. Given that T1D is associated with other autoimmune diseases,
Nick Thomas +8 more
wiley +1 more source
Problems of systemic connective tissue diseases of childhood in historical perspective
Научно-практическая ревматологияThe relevance of study systemic connective tissue diseases with juvenile onset for modern medicine is determined by the trend towards their growth in the population, the difficulty of early diagnosis, the rapid development of disability and a poor life ...
M. I. Kaleda, I. P. Nikishina
doaj +1 more source
A meta-analysis of public microarray data identifies gene regulatory pathways deregulated in peripheral blood mononuclear cells from individuals with Systemic Lupus Erythematosus compared to those without [PDF]
, 2016 BACKGROUND: Systemic Lupus Erythematosus (SLE) is a complex, multi-systemic, autoimmune disease for which the underlying aetiological mechanisms are poorly understood.
Entfellner, Jean-Baka Domelevo +3 more
core +3 more sources
Lupus nephritis management guidelines compared [PDF]
, 2015 In the past years, many (randomized) trials have been performed comparing the treatment strategies for lupus nephritis. In 2012, these data were incorporated in six different guidelines for treating lupus nephritis.
Bajema, IM +7 more
core +1 more source
Hypergammaglobulinemia in the pediatric population as a marker for underlying autoimmune disease: a retrospective cohort study [PDF]
, 2014 Background: The significance of hypergammaglobulinemia as a marker of immune activation is unknown, as a differential diagnosis for hypergammaglobulinemia in children has not been adequately established.
Lo, Mindy S +3 more
core +1 more source
Cutaneous manifestations of juvenile onset lupus erythematosus: A clinical study
Indian Journal of Paediatric Dermatology, 2018 Introduction: Juvenile-onset systemic lupus erythematosus (SLE) is one of the most common systemic autoimmune connective tissue disorders in children.
Vinitha Panicker +5 more
doaj +1 more source
Cardiovascular disease in latin american patients with systemic lupus erythematosus: a cross-sectional study and a systematic review [PDF]
, 2013 Objective. This study was performed to determine the prevalence of and associated risk factors for cardiovascular disease (CVD) in Latin American (LA) patients with systemic lupus erythematosus (SLE). Methods.
Amaya-Amaya, Jenny-Carolina +6 more
core +3 more sources
Assessment of hematologic indices for diagnosis in juvenile systemic lupus erythematosus
RheumatologyIntroduction The aim was to present effective approaches utilizing novel hematological parameters for early diagnosis of juvenile-onset systemic lupus erythematosus (jSLE).
Gülcan Özomay Baykal +2 more
doaj +1 more source
How does age at onset influence the outcome of autoimmune diseases? [PDF]
, 2014 The age at onset refers to the time period at which an individual experiences the first symptoms of a disease. In autoimmune diseases (ADs), these symptoms can be subtle but are very relevant for diagnosis.
Amador-Patarroyo, Manuel-José +2 more
core +1 more source
Pediatric Rheumatology Online Journal, 2018 Background Proteinuria is a well-known risk factor for progression of renal dysfunction in a variety of chronic kidney diseases. In adult-onset Systemic Lupus Erytematosus (SLE) patients with lupus nephritis (LN), proteinuria takes a significant period ...
Eve M. D. Smith +4 more
doaj +1 more source