Results 111 to 120 of about 18,031 (200)

Monogenic forms of systemic lupus erythematosus: new insights into SLE pathogenesis

Pediatric Rheumatology Online Journal, 2012
The pathogenesis of Systemic Lupus Erythematosus (SLE) is complex and remains poorly understood. Infectious triggers, genetic background, immunological abnormalities and environmental factors are all supposed to interact for the disease development ...
Belot Alexandre, Cimaz Rolando
doaj   +1 more source

Assessment of Type I Interferon Signaling in Pediatric Inflammatory Disease [PDF]

, 2017
International audiencePURPOSE: Increased type I interferon is considered relevant to the pathology of a number of monogenic and complex disorders spanning pediatric rheumatology, neurology, and dermatology.
A Brehm, AL Mathieu, Alexandre Belot, Anthony Oojageer, Brigitte Bader-Meunier, CD Conrad, Christine Bodemer, D Tonduti, DM Santer, E Lausch, EC Baechler, EC Baechler, F Allantaz, F Goutieres, GI Rice, GI Rice, GI Rice, GI Rice, Gillian I. Rice, Isabelle Melki, J Hua, JH Livingston, L Bennett, M Berger Rentsch, M Henneke, MA Jang, Marie-Louise Frémond, Mathieu P. Rodero, ME Meuwissen, MP Rodero, Naoki Kitabayashi, P Lebon, P Navon Elkan, P Quartier, P Starokadomskyy, Pierre Quartier, PK Chakraborty, Q Zhou, R Banchereau, S Oon, SA Greenberg, SC Eckard, SM Al-Mayouf, TA Briggs, TB Niewold, Tracy A. Briggs, V Sisirak, X Zhang, Y Li, Y Liu, Yanick J. Crow, YJ Crow, YJ Crow, YJ Crow, YJ Crow, YJ Seo   +55 more
core   +4 more sources

Undifferentiated connective tissue disease: a seven-center cross-sectional study of 184 patients [PDF]

, 2009
The purpose of this study was to characterize the clinical and serological features of a large cohort of patients with antinuclear antibody (ANA) positive undifferentiated connective tissue disease (UCTD).
Barcelos, A, Barros, R, Costa, J, Couto, M, Inês, L, Medeiros, D, Miranda, L, Nero, P, Santos, MJ, Sousa, E, Vaz, CC   +10 more
core   +1 more source

Advances in paediatrics in 2016: Current practices and challenges in allergy, autoimmune diseases, cardiology, endocrinology, gastroenterology, infectious diseases, neonatology, nephrology, neurology, nutrition, pulmonology [PDF]

, 2017
This review reports main progresses in various pediatric issues published in Italian Journal of Pediatrics and in international journals in 2016. New insights in clinical features or complications of several disorders may be useful for our better ...
Bernasconi, Sergio, Caffarelli, Carlo, Di Mauro, Dora, Mastrorilli, Carla, Montella, Silvia, Santamaria, Francesca   +5 more
core   +2 more sources

Childhood-onset systemic lupus erythematosus in Croatia: demographic, clinical and laboratory features, and factors influencing time to diagnosis [PDF]

, 2013
OBJECTIVES Childhood-onset systemic lupus erythematosus (cSLE) presents with diverse clinical features and often with non-classical symptoms that may delay diagnosis and increase risk of morbidity and mortality.
Batinić, Danica, Jelušić, Marija, Lukić, Anita, Lukić, Ivan Krešimir, Malenica, Branko, Malčić, Ivan, Metličić, Vitomir, Milošević, Danko, Rožmanić, Vojko, Saraga, Marijan, Šubat-Dežulović, Mirna   +10 more
core  

Heterogeneity of macrophage activation syndrome and treatment progression

Frontiers in Immunology
Macrophage activation syndrome (MAS) is a rare complication of autoimmune inflammatory rheumatic diseases (AIIRD) characterized by a progressive and life-threatening condition with features including cytokine storm and hemophagocytosis.
Yuanji Dong, Ting Wang, Huaxiang Wu
doaj   +1 more source

Health Related Quality of Life in Juvenile-Onset Systemic Lupus Erythematosus: A Questionnaire-Based Study. [PDF]

Matern Child Health J, 2023
Eid R, Hammad A, Korkor MS, Fathy AA, Abd El-Ghafaar DM, Rakha S, Hamdy N.   +6 more
europepmc   +1 more source

Case report: Single infusion of combined anti-CD20 and anti-CD38 monoclonal antibodies in pediatric refractory lupus nephritis

Frontiers in Immunology
Lupus nephritis (LN), present in 30%–50% of systemic lupus erythematosus (SLE) patients, often necessitates standard immunosuppressive therapy (glucocorticoids, MMF, CYC) as suggested by the European League Against Rheumatism/European Renal Association ...
Decimo Silvio Chiarenza, Raul Mancini, Carolina Bigatti, Carolina Bigatti, Gianluca Caridi, Alessandro Consolaro, Alessandro Consolaro, Valentina Natoli, Valentina Natoli, Gabriele Mortari, Xhuliana Kajana, Francesca Lugani, Marco Gattorno, Marco Gattorno, Gian Marco Ghiggeri, Edoardo La Porta, Gabriele Gaggero, Enrico E. Verrina, Andrea Angeletti   +18 more
doaj   +1 more source

IL12B and IL17 genes polymorphisms associated with differential susceptibility to juvenile idiopathic arthritis and juvenile-onset systemic lupus erythematosus in Chinese children. [PDF]

Medicine (Baltimore), 2023
Zhang M, Peng L, Li W, Duan Y, Liu X, Chen S, Deng J, Liu X.   +7 more
europepmc   +1 more source

Risk factors for subsequent lupus nephritis in patients with juvenile-onset systemic lupus erythematosus: a retrospective cohort study. [PDF]

Pediatr Rheumatol Online J, 2023
Hsu TC, Yang YH, Wang LC, Lee JH, Yu HH, Lin YT, Hu YC, Chiang BL.   +7 more
europepmc   +1 more source