Results 111 to 120 of about 530,157 (260)

Efficacy and Safety of Abatacept Versus Placebo During Peanut Oral Immunotherapy for Adults With Severe Peanut Allergy

Allergy, EarlyView.
In this Phase 2a trial, severely peanut‐allergic participants were randomized to abatacept versus placebo with peanut oral immunotherapy (OIT) for 24 weeks, followed by 12 weeks of OIT alone. No significant difference was observed for the primary efficacy outcome (the relative change from baseline in peanut‐specific/total IgE ratio at 24 weeks), but ...
Marie‐Lee Simard, Camille Braun, Éloise Antony, Émilie Roy, Marie‐Ève Gingras, François Graham, Anne Des Roches, Louis Paradis, Kathryn Samaan, Florence Gingras‐Lessard, Roxane Labrosse, Thomas Eiwegger, Philippe Bégin   +12 more
wiley   +1 more source

Case Report: Early-onset juvenile psoriatic arthritis presenting at 15 months—a diagnostic challenge in infancy

Frontiers in Pediatrics
This case describes a rare early-onset presentation in a 15-month-old girl, who first developed guttate psoriatic lesions followed by knee arthritis confirmed by ultrasound. The patient had a strong family history of autoimmune diseases.
Lana Hasasna, Mayar Atawneh, Math Atiani, Mohammad Alami, Fawzy M. Abunejma   +4 more
doaj   +1 more source

Radiographic measurements of cardiac silhouette and skeletal landmarks in companion galahs (Eolophus roseicapilla) and sulphur‐crested cockatoos (Cacatua galerita)

Australian Veterinary Journal, EarlyView.
Introduction Cardiac disease is common in companion birds, yet its diagnosis remains a challenge due to limited validated tests. Radiography is frequently used to assess cardiac size in birds; however, interspecies variation necessitates species‐specific reference intervals.
P Narayanan, KW Kun, R Ahn, J Henning, RJT Doneley   +4 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Micrognathia

, 1999
This is a photograph of an 11 year old girl with pronounced micrognathia as a result of bilateral temporo - mandibular arthritis in longstanding juvenile rheumatoid arthritis.

core  

Charting the course of Sjögren's disease: A historical analysis of scientific progress

European Journal of Oral Sciences, EarlyView.
Abstract Sjögren's disease (SjD) bears the name of the Swedish ophthalmologist Henrik Sjögren. His 1933 doctoral thesis on keratoconjunctivitis sicca ignited interest, yet much remains under debate. SjD is an autoimmune disorder that primarily affects the exocrine glands, particularly the salivary and lacrimal glands, leading to a dryness of the eyes ...
Diego Ustárroz Cantali, Fabiola Reis de Oliveira, Denise Cantarelli Machado, Moisés Evandro Bauer   +3 more
wiley   +1 more source

Targeting the chemokine receptor CXCR4 with histamine analog to reduce inflammation in juvenile arthritis. [PDF]

Front Immunol, 2023
Bekaddour N, Smith N, Beitz B, Llibre A, Dott T, Baudry A, Korganow AS, Nisole S, Mouy R, Breton S, Bader-Meunier B, Duffy D, Terrier B, Schneider B, Quartier P, Rodero MP, Herbeuval JP.   +16 more
europepmc   +1 more source

Healthcare Professional Identified Priorities for a New Musculoskeletal Examination Scoring System for People With Hemophilia—an International Consensus

Haemophilia, EarlyView.
ABSTRACT Introduction The accurate physical examination of musculoskeletal (MSK) health is an essential part of proactive best practice care of people with hemophilia and must be consistently monitored in clinic. In response to current MSK tool limitations, the Musculoskeletal Health Expert Working Group (MSKH EWG) of the International Prophylaxis ...
Lizabeth Teshler, Audrey Abad, Magnus Aspdahl, Laura Avila, Melanie Bladen, Sharon Funk, Pamela Hilliard, Judy Ann John, Marilyn Manco‐Johnson, Janjaap van der Net, David Stephensen, Jean St‐Louis, Merel Timmer, Beth Boulden Warren, F. Virginia Wright, Nichan Zourikian, Brian M. Feldman   +16 more
wiley   +1 more source

The Effect of PTPN22 Polymorphism on Juvenile Idiopathic Arthritis Subtypes and Disease Activity in a Finnish Study Population

International Journal of Immunogenetics, EarlyView.
ABSTRACT Genetic factors that modulate immune regulation are increasingly recognised as contributors to the heterogeneity and clinical course of autoimmune diseases. Polymorphisms of protein tyrosine phosphatase non‐receptor type 22 (PTPN22) are associated with several autoimmune diseases.
Sonja Kvist, Johanna Teräsjärvi, Heidi Rahikkala, Jussi Mertsola, Milja Möttönen, Qiushui He   +5 more
wiley   +1 more source

Physical activity in children with juvenile idiopathic arthritis: a review of recent literature

Juvenile idiopathic arthritis is the most common rheumatic chronic disease in children, typically characterised by joint pain and swelling, fatigue, stiffness, muscle weakness and movement restrictions.
Aleksandra Stasiak, Agnieszka Małgorzata Wosiak, Elżbieta Smolewska   +2 more
core   +1 more source