Results 101 to 110 of about 530,157 (260)

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Time to move: arthritis

, 2014
The strategy outlined in this document provides a road map for improving care across Australia for people with arthritis and aims to reduce the costs to society of arthritis related diseases.

core  

Toll‐Like Receptor 4 Signaling in Natural N‐Acylethanolamines and Derivative NAE‐Like Compounds: Mechanisms and Implications for Neuroimmune and Inflammatory Processes in a Systematic Search Approach

Phytotherapy Research, EarlyView.
ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri, Francesca Guida, Giacinto Bagetta, Sabatino Maione, Maria Tiziana Corasaniti, Morena Zusso   +5 more
wiley   +1 more source

Treatment of refractory juvenile idiopathic arthritis via pulse therapy using methylprednisolone and cyclophosphamide

São Paulo Medical Journal
CONTEXT: Patients with refractory juvenile idiopathic arthritis can benefit from aggressive therapy. CASE REPORT: We followed the clinical course of 4 patients (2 male, 2 female) aged 9.1-17.8 years (mean of 14.5 years) with polyarticular onset of ...
Tania Caroline Monteiro de Castro, Maria Teresa Terreri, Claudio Len, Maria Odete Esteves Hilário   +3 more
doaj   +1 more source

CLINICAL BLOOD IN PATIENTS WITH JUVENILE IDIOPATHIC ARTHRITIS IN KRASNOYARSK REGION

Siberian Journal of Life Sciences and Agriculture, 2019
The aim of the study – assessment of the features of clinical blood in patients with juvenile idiopathic arthritis. It showed an increase in the absolute number of lymphocytes and monocytes, platelets, neutrophils, increased erythrocyte sedimentation ...
Julia Semenovna Akopova, Olga Mikhailovna Miller, Semenovna Irena Akopova   +2 more
doaj   +1 more source

Microbiota as the candidate biomarker in pediatric obstructive sleep apnea

Sleep Research, EarlyView.
Abstract Pediatric obstructive sleep apnea (OSA) is a form of sleep‐disordered breathing in children. Recent studies have focused on characterizing microbiota alterations associated with pediatric OSA and identifying microbial features that may have potential value as future biomarkers. The most commonly used approach for microbiota profiling is second‐
Xiaoyan Li, Jingxuan Bai, Ying Xu, Min Yu, Xuemei Gao   +4 more
wiley   +1 more source

A national registry for juvenile dermatomyositis and other paediatric idiopathic inflammatory myopathies: 10 years' experience; the Juvenile Dermatomyositis National (UK and Ireland) Cohort Biomarker Study and Repository for Idiopathic Inflammatory Myopathies [PDF]

, 2010
Objectives: The paediatric idiopathic inflammatory myopathies (IIMs) are a group of rare chronic inflammatory disorders of childhood, affecting muscle, skin and other organs.
Juvenile Dermatomyositis Research Group, Martin, N, Lucy R. Wedderburn, Sally Smith, Davidson, J.E., Wedderburn, L.R., Smith, S., Neil Martin, Pilkington, C.A., Gardner-Medwin, J. [JD Research Group], Joyce E. Davidson, Krol, P., Petra Krol, Murray, K., Kevin Murray, Clarissa A. Pilkington   +15 more
core   +1 more source

Disease of South American camelids in England and Wales: Analysis of diagnoses from Animal and Plant Health Agency laboratory submissions between 2012 and 2021

Veterinary Record, EarlyView.
Abstract Background South American camelids (SACs) have become increasingly popular in the UK. Consequently, knowledge among veterinary practitioners about diseases in these non‐native species has improved, although gaps remain. The remit of this study was to identify common diseases of SACs based on Animal and Plant Health Agency (APHA) surveillance ...
Sonja Jeckel, Carissa Xian Chow, David Jorge   +2 more
wiley   +1 more source

Economic Burden and Treatment Patterns Among Patients Diagnosed With Vitiligo in Japan: An Observational Retrospective Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Vitiligo, a common and chronic depigmentation disorder, significantly impacts patients' quality of life and exerts a substantial economic burden. The deleterious impact of vitiligo can be exacerbated by comorbid conditions, including psychiatric and autoimmune conditions.
Naoki Oiso, Kent A. Hanson, Ahmed M. Soliman, Chao Li, Manabu Taura, Daniel Mercer, Andrew Rava, Danielle Bynoe, Haiyan Sun, Tamio Suzuki   +9 more
wiley   +1 more source

Multicenter Clinical Comparison Between Anti‐NXP2 and Anti‐TIF1‐γ Antibody‐Positive Myositis, and Analysis of the Clinical Significance of Anti‐NXP2 Antibody Titers in Idiopathic Inflammatory Myopathies

The Journal of Dermatology, EarlyView.
ABSTRACT We aimed to measure anti‐nuclear matrix protein 2 antibody (anti‐NXP2) titers in patients with anti‐NXP2‐positive idiopathic inflammatory myopathies, investigate whether these titers are associated with clinical manifestations, malignancy risk, and treatment response, and compare the clinical and serological features between anti‐NXP2‐positive
Satoshi Kamiya, Mariko Ogawa‐Momohara, Yoshinao Muro, Yuta Yamashita, Satoko Yuasa, Masato Kakeda, Kimiko Nakajima, Hiroyuki Morita, Mitsuyo Kinjo, Takako Hashimoto, Ken Yoshida, Takuya Takeichi, Haruka Koizumi, Norika Akashi, Eori Noda, Masashi Akiyama   +15 more
wiley   +1 more source