Results 121 to 130 of about 41,818 (235)

Serious Infection in Crohn's Disease Patients Treated With Ustekinumab: US Food and Drug Administration Active Postmarket Risk Identification and Analysis in the Sentinel Initiative

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1514-1521, June 2026.
The U.S. Food and Drug Administration (FDA) used an Active Postmarket Risk Identification and Analysis (ARIA) system to address a safety issue (serious infection) identified during clinical review of an application to market ustekinumab as a treatment for Crohn's disease (CD). FDA used an active‐comparator new‐user cohort design, data from six Sentinel
Joel L. Weissfeld, Geetha S. Iyer, Suna C. Seo, Andrew Giffin, Andrew L. Simon, Sheryl A. Kluberg, Emma R. Hoffman, Jamal T. Jones, Sarah K. Dutcher, Joyce A. Korvick   +9 more
wiley   +1 more source

Juvenile rheumatoid arthritis (Juvenile chronic arthritis)

Dermatology Online Journal, 2001
openaire   +4 more sources

Modeling, Simulation, and Extrapolation to Optimize Pediatric Development Plan: Sarilumab Polyarticular-Course juvenile arthritis Application. [PDF]

J Pharmacokinet Pharmacodyn
Xu C, Zhang M, Liu Y, Baret-Cormel L, De Benedetti F, Abdallah H, Kanamaluru V, Meng Z.   +7 more
europepmc   +1 more source

Assessing joint damage in juvenile idiopathic arthritis: Guide for prescribing physical exercise with the juvenile arthritis damage index. [PDF]

World J Clin Pediatr
Dos Santos WR.
europepmc   +1 more source

Juvenile arthritis damage index predicts poor response to biological treatment: A prospective cohort study. [PDF]

World J Clin Pediatr
Kolkhidova ZA, Nikishina IP, Glukhova SI, Melikhov OG, Kostik MM.   +4 more
europepmc   +1 more source

Association Between Systemic Immune‐Inflammation Index and Sepsis‐Induced Liver Injury in Adult Patients With Sepsis: A Retrospective Cohort Study

Immunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
ABSTRACT Background Sepsis‐induced liver injury (SILI) is a fatal complication of organ failure that currently lacks reliable biomarkers for early diagnosis and risk prediction. This study aimed to explore the link between the systemic immune‐inflammatory index (SII) and SILI in adult patients with sepsis in the intensive care unit (ICU) at Nanjing ...
Zimeng Qin, Jiaqi Li, Yijiang Liu, Beiyuan Zhang, Wenkui Yu   +4 more
wiley   +1 more source

Correction: A novel LACC1 variant c.658G > A (p.Asp220Asn) in familial juvenile arthritis: identification and functional analysis. [PDF]

Hum Genomics
Alblooshi H, Mustafa N, Khalam AA, Bharathan A, Mohammed E, Baydoun I, Tabouni M, Allam M, Almansoori M, Fatima T, Aljaberi N.   +10 more
europepmc   +1 more source

Tocilizumab and Dexamethasone Reduce TNF‐α and IL‐33 and Oxidative Stress in Kidney Tissue in Oleic Acid‐Induced ARDS Model

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
Oleic acid causes ARDS‐associated AKI. Tocilizumab and dexamethasone reduces ARDS‐induced kidney injury. The width of the filtration slits increases in kidney injury. Tocilizumab and dexamethasone suppress TNF‐a and IL‐33. ABSTRACT The most common extrapulmonary organ injury in cases of acute respiratory distress syndrome (ARDS) is acute kidney injury (
Huseyin Serkan Erol, Beste Demirci, Mohammad Alhilal, Funda Terzi, Nazli Kelercioglu   +4 more
wiley   +1 more source

Parent and Physician Global Assessment Discordance in Juvenile Arthritis: The Role of Pain Coping Strategies. [PDF]

J Pediatr Clin Pract
Backström M, Halttu A, Tarkiainen M, Lehtinen E, Sard S, Keskitalo P, Markula-Patjas K, Rebane K, Aalto K, Remes-Pakarinen T, Kärki J, Hietanen M, Pohjankoski H, Korkatti K, Kosonen E, Löyttyniemi E, Malin M, Kröger L, Vähäsalo P.   +18 more
europepmc   +1 more source

Relaxation Time Mapping of Early‐Stage Osteonecrosis of the Femoral Head: An In Vivo Piglet Model Study

Journal of Orthopaedic Research, Volume 44, Issue 6, June 2026.
T2, T1ρ, adiabatic T1ρ, and adiabatic T2ρ relaxation time mapping techniques are sensitive in detecting ischemic injury to bone marrow of the femoral head in vivo in a piglet model at 3 T MRI. T2 and adiabatic T2ρ relaxation times have the most pronounced increase in ischemic versus perfused, contralateral‐control femoral heads 1 week after induction ...
Casey P. Johnson, Erick O. Buko, Sampada Bhave, Kayla L. Chase, Douglas Albrecht, Alexandra R. Armstrong, Jutta M. Ellermann, Harry K. W. Kim, Ferenc Tóth   +8 more
wiley   +1 more source