A fatal interstitial lung disease in an anti-melanoma differentiation-associated gene 5 (anti-MDA5) antibody negative patient with juvenile dermatomyositis [PDF]
The Turkish Journal of Pediatrics, 2021 Background. Juvenile dermatomyositis associated interstitial lung disease, rarely seen in pediatric age groups, has adverse effects on survival.
Osman Yeşilbaş +9 more
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JUVENILE DERMATOMYOSITIS [PDF]
Romanian Journal of Pediatrics, 2016 Juvenile dermatomyositis is a severe multisystemic autoimmune disease of uncertain origin, based on chronic perivascular inflammation, involving mainly the skin and the muscles.
Sigrid Covaci +2 more
doaj +5 more sources
Journal of Rheumatic Diseases, 2022 Juvenile dermatomyositis (JDM) is a systemic capillary vasculopathy. Patients present with proximal muscle weakness, raised muscle enzymes, and pathognomic skin rashes such as heliotrope rash, Gottron’s papules.
Jung-Woo Rhim
semanticscholar +5 more sources
Calcinosis in juvenile dermatomyositis: Updates on pathogenesis and treatment
Frontiers in Medicine, 2023 Calcinosis, or the deposition of insoluble calcium salts in the skin, subcutaneous tissue, fascia, tendons, and muscles, is a feared complication of juvenile dermatomyositis.
Caitlan S. Pinotti +4 more
doaj +2 more sources
Frontiers in Pediatrics, 2022 Objective To determine the short-term effectiveness safety of baricitinib in children with refractory and/or severe juvenile dermatomyositis (rsJDM) in a real-world setting. Methods This was a single-center retrospective study, including 20 children with
Zhaoling Wang +8 more
openalex +2 more sources
SAGE Open Medical Case Reports, 2022 Juvenile dermatomyositis is a rare autoimmune myopathy of childhood, associated with systemic vasculopathy, primarily affecting the capillaries. Panniculitis is seen histologically in about 10% of patients with dermatomyositis; however, its clinical ...
Dylan C Ginter +5 more
doaj +2 more sources
Respiratory symptoms as initial manifestations of interstitial lung disease in clinically amyopathic juvenile dermatomyositis: a case report with literature review [PDF]
BMC Pediatrics, 2021 Background Clinically amyopathic juvenile dermatomyositis (CAJDM) is a clinical subgroup of juvenile dermatomyositis (JDM), characterized by JDM rashes with little or no clinically evident muscle weakness.
Jingyi Xia +6 more
doaj +2 more sources
Anti-nuclear matrix protein 2 antibody-associated juvenile dermatomyositis with gastrointestinal perforations was successfully treated with traditional therapeutic drugs combined with vedolizumab: a case report after a long-term follow-up and a review of the literature [PDF]
Frontiers in PediatricsGastrointestinal perforation in patients with juvenile dermatomyositis has been reported as a life-threatening complication in the literature. However, effective treatment of juvenile dermatomyositis with gastrointestinal perforation remains challenging.
Xue-mei Xu +8 more
doaj +2 more sources
The Significance of Autoantibodies in Juvenile Dermatomyositis [PDF]
BioMed Research International, 2021 Juvenile dermatomyositis is a chronic and rare autoimmune disorder classified into the spectrum of idiopathic inflammatory myopathies. Although this entity is mainly characterized by the presence of pathognomonic cutaneous lesions and proximal muscle ...
Dominika Kwiatkowska, Adam Reich
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Current evidence for janus kinase inhibitors in adult and juvenile dermatomyositis and key comparisons. [PDF]
Expert Opin PharmacotherIntroduction Adult dermatomyositis (DM) and juvenile dermatomyositis (JDM) are rare autoimmune diseases with characteristic skin rashes, weakness, and other systemic features. Upregulated interferon signaling has been consistently described in both adult
Wallwork RS, Paik JJ, Kim H.
europepmc +2 more sources