Results 31 to 40 of about 5,034 (114)

Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis

Arthritis &Rheumatology, Accepted Article.
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the non‐coding genome in disease pathogenesis.
Rayan Najjar, Andrew Mammen, Tomas Mustelin   +2 more
wiley   +1 more source

Inflammatory Myopathies with Cutaneous Involvement: from Diagnosis to Therapy

Folia Medica, 2017
The group of idiopathic inflammatory myopathies (IIM) include various disorders of skeletal muscles with or without skin involvement. The most common types are dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM) and necrotizing ...
Dourmishev Lyubomir A.
doaj   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Porto‐sinusoidal vascular disorder in a pediatric patient with prolidase deficiency: A case report

JPGN Reports, EarlyView.
Abstract Prolidase deficiency (PD) is a rare autosomal recessive disorder affecting collagen turnover, leading to diverse clinical manifestations including dermatologic lesions, hepatosplenomegaly, and vascular anomalies. Liver involvement in PD is poorly understood, with few reported cases.
Melissa Castro, Christian Martinez, Carole Brathwaite, Reuven Bromberg, Ana M. Rodriguez, Erick Hernandez   +5 more
wiley   +1 more source

Dermatomyositis: A Multifaceted Autoimmune Connective Tissue Disorder: Series of Seven Cases

Clinical Dermatology Review
Dermatomyositis is a rare connective tissue disorder having a wide array of characteristic cutaneous and systemic manifestations. There is an established paraneoplastic association of malignancy with dermatomyositis which is seen in adult patients as ...
Mrunali Anil Joshi, Pooja Agarwal, Kalgi Baxi, Raju Gisaram Chaudhary, Vama Vijay Patel   +4 more
doaj   +1 more source

Obesity as a Risk Factor for Autoimmune Diseases: A Systematic Review and Meta‐Analysis

Obesity, EarlyView.
Summary of the meta‐analysis including 26 studies (8 cross‐sectional, 18 longitudinal) investigating the association between obesity and autoimmune diseases. Findings show increased prevalence and incidence of rheumatoid arthritis, psoriasis, multiple sclerosis, and inflammatory bowel diseases in people with obesity, suggesting that obesity may ...
Ilaria Spatocco, Giorgia Mele, Giusy De Rosa, Clorinda Fusco, Kristyna Ruggiero, Valeria Pellegrini, Francesca Carreras, Rosalba La Grotta, Antonio Ceriello, Claudio Procaccini, Giuseppe Matarese, Francesco Prattichizzo, Paola de Candia   +12 more
wiley   +1 more source

Anasarca as the presenting symptom of juvenile dermatomyositis: a case series

Pediatric Rheumatology Online Journal, 2021
Background Juvenile Dermatomyositis (JDM) is an autoimmune disease that typically presents with classic skin rashes and proximal muscle weakness. Anasarca is a rare manifestation of this disease and is associated with a more severe and refractory course,
Emily E. Schildt, Deirdre De Ranieri
doaj   +1 more source

Macrophage activation syndrome due to juvenile amyopathic dermatomyositis with atypical onset

Turkderm Turkish Archives of Dermatology and Venereology, 2022
Macrophage activation syndrome (MAS) is a life-threatening condition associated with rheumatic diseases. It is rarely reported in juvenile dermatomyositis.
Esma İnan Yüksel, Betül Demir, Metin kaya Gürgöze, Ilknur Calik   +3 more
doaj   +1 more source

The effect of blended tube feeding compared to conventional formula on clinical outcomes in adults: A systematic review

Nutrition &Dietetics, EarlyView.
Abstract Aim To explore the effect of blended tube feeding compared to conventional formulas on nutritional status, quality of life, anthropometry, diarrhoea and tube blockages in adults receiving tube feeding. Methods The protocol was registered (PROSPERO CRD42022372443).
Lina Breik, Lisa Barker, Judy Bauer, Zoe E. Davidson   +3 more
wiley   +1 more source

Superimposed segmental manifestation of juvenile amyopathic dermatomyositis in a 9-year-old boy

Indian Journal of Dermatology, 2017
Dermatomyositis is a well-known autoimmune disorder. On the other hand, juvenile amyopathic dermatomyositis (JADM) occurs rather rarely. Here, we report an unusual case in a 9-year-old Turkish boy showing a unilateral linear inflammatory skin lesion that
Isil Bulur, Hilal Kaya Erdogan, Zeynep Nurhan Saracoglu, Rudolf Happle, Funda Canaz   +4 more
doaj   +1 more source