Results 41 to 50 of about 346,856 (231)

Updates on interferon in juvenile dermatomyositis: pathogenesis and therapy

open access: yesCurrent Opinion in Rheumatology, 2021
Purpose of review This review provides updates regarding the role of interferon (IFN) in juvenile dermatomyositis (JDM), including comparison to interferonopathies and therapeutic implications.
Hanna Kim
semanticscholar   +1 more source

Scanning for therapeutic targets within the cytokine network of idiopathic inflammatory myopathies [PDF]

open access: yes, 2015
The idiopathic inflammatory myopathies (IIM) constitute a heterogeneous group of chronic disorders that include dermatomyositis (DM), polymyositis (PM), sporadic inclusion body myositis (IBM) and necrotizing autoimmune myopathy (NAM).
De Paepe, Boel, Zschüntzsch, Jana
core   +3 more sources

Features distinguishing clinically amyopathic juvenile dermatomyositis from juvenile dermatomyositis [PDF]

open access: yesRheumatology, 2018
We examined features of clinically amyopathic JDM (CAJDM), in which patients have characteristic rashes with little to no evidence of muscle involvement, to determine whether this is a distinct phenotype from JDM.Demographic, clinical, laboratory and treatment data from 12 (9 hypomyopathic, 3 amyopathic) patients meeting modified Sontheimer criteria ...
Gulnara Mamyrova   +28 more
openaire   +2 more sources

The Vasculopathy of Juvenile Dermatomyositis: Endothelial Injury, Hypercoagulability, and Increased Arterial Stiffness

open access: yesArthritis & Rheumatology, 2021
Vasculopathy is considered central to the pathogenesis of juvenile dermatomyositis (DM) and is associated with severe extramuscular manifestations.
C. Papadopoulou   +7 more
semanticscholar   +1 more source

Biomarkers in Inflammatory Myopathies – An Expanded Definition [PDF]

open access: yes, 2019
Biomarkers as parameters of pathophysiological conditions can be of outmost relevance for inflammatory myopathies. They are particularly warranted to inform about diagnostic, prognostic, and therapeutic questions.
Benveniste, Olivier   +2 more
core   +3 more sources

Nodular Regenerative Hyperplasia of the liver in Juvenile Dermatomyositis

open access: yesPediatric Rheumatology Online Journal, 2022
Background We present two cases of Nodular Regenerative Hyperplasia (NRH) associated with Juvenile Dermatomyositis (JDM). Case Presentation Case 1: A nine-year-old Caucasian male with refractory JDM and anti-NXP2 autoantibodies was diagnosed at age two ...
Aviya Lanis   +6 more
semanticscholar   +1 more source

Clinical and autoantibody phenotypes of juvenile dermatomyositis

open access: yesRheumatology, 2022
Juvenile dermatomyositis (JDM) is a heterogeneous autoimmune inflammatory myositis with symmetrical proximal muscle weakness and a characteristic rash. Juvenile dermatomyositis is characterized by variable presentation and phenotypes.
O. Boyarchuk, Anna Kuka, Iryna Yuryk
semanticscholar   +1 more source

Multi-Modal Single-Cell Sequencing Identifies Cellular Immunophenotypes Associated With Juvenile Dermatomyositis Disease Activity

open access: yesFrontiers in Immunology, 2021
Juvenile dermatomyositis (JDM) is a rare autoimmune condition with insufficient biomarkers and treatments, in part, due to incomplete knowledge of the cell types mediating disease.
J. Neely   +7 more
semanticscholar   +1 more source

Resolution of calcinosis using bisphosphonates in overlap syndrome – a case report

open access: yesBMC Rheumatology, 2021
Introduction Calcinosis cutis is a common complication of pediatric rheumatologic diseases. However, there is currently no consensus on first-line treatment.
Mitchell Platter   +2 more
doaj   +1 more source

Risk factors associated with calcinosis of juvenile dermatomyositis [PDF]

open access: yes, 2008
OBJETIVO: Identificar fatores de risco associados à calcinose em crianças e adolescentes com dermatomiosite juvenil. MÉTODOS: Prontuários de 54 pacientes com dermatomiosite juvenil foram estudados.
AIKAWA, Nádia E.   +6 more
core   +3 more sources

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