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The study objective was to identify differences in gene expression between treatment responders (TRs) and treatment non‐responders (TNRs) diagnosed with juvenile dermatomyositis (JDM).
C. Stingl+8 more
semanticscholar +1 more source
OBJECTIVE: To analyze major histocompatibility complex expression in the muscle fibers of juvenile and adult dermatomyositis. METHOD: In total, 28 untreated adult dermatomyositis patients, 28 juvenile dermatomyositis patients (Bohan and Peter's criteria)
Samuel Katsuyuki Shinjo+3 more
doaj +1 more source
Clinical phenotypes and biologic treatment use in juvenile dermatomyositis-associated calcinosis [PDF]
Background Few risk factors have been identified for the development of calcinosis among patients with Juvenile Dermatomyositis, and currently no clinical phenotype has been associated with its development.
Al-Hammadi, Noor+4 more
core +2 more sources
Juvenile Dermatomyositis: New Clues to Diagnosis and Therapy
To identify clues to disease activity and discuss therapy options. The diagnostic evaluation includes documenting symmetrical proximal muscle damage by exam and MRI, as well as elevated muscle enzymes—aldolase, creatine phosphokinase, LDH, and SGOT—which
L. Pachman+3 more
semanticscholar +1 more source
Risk factors associated with calcinosis of juvenile dermatomyositis [PDF]
OBJETIVO: Identificar fatores de risco associados à calcinose em crianças e adolescentes com dermatomiosite juvenil. MÉTODOS: Prontuários de 54 pacientes com dermatomiosite juvenil foram estudados.
AIKAWA, Nádia E.+6 more
core +3 more sources
Scanning for therapeutic targets within the cytokine network of idiopathic inflammatory myopathies [PDF]
The idiopathic inflammatory myopathies (IIM) constitute a heterogeneous group of chronic disorders that include dermatomyositis (DM), polymyositis (PM), sporadic inclusion body myositis (IBM) and necrotizing autoimmune myopathy (NAM).
De Paepe, Boel, Zschüntzsch, Jana
core +3 more sources
Vitamin D supplementation in the pediatric rheumatology clinic. [PDF]
Vitamin D is capturing the attention of healthy and chronically ill populations for its potential skeletal and nonskeletal benefits. New information suggesting a role in immune modulation has led to a surge of interest among rheumatologists. Although the
Burnham, Jon M, von Scheven, Emily
core +3 more sources
In juvenile dermatomyositis (JDM), the most common pediatric inflammatory myopathy, weakness is accompanied by a characteristic rash that often becomes chronic and is associated with vascular damage.
E. Roberson+5 more
semanticscholar +1 more source
Resolution of calcinosis using bisphosphonates in overlap syndrome – a case report
Introduction Calcinosis cutis is a common complication of pediatric rheumatologic diseases. However, there is currently no consensus on first-line treatment.
Mitchell Platter+2 more
doaj +1 more source
Comparison of the Utility and Validity of Three Scoring Tools to Measure Skin Involvement in Patients With Juvenile Dermatomyositis [PDF]
OBJECTIVE: To compare the abbreviated Cutaneous Assessment Tool (CAT), Disease Activity Score (DAS), and Myositis Intention to Treat Activity Index (MITAX) and correlate them with the physician's 10-cm skin visual analog scale (VAS) in order to define ...
Almeida, B+9 more
core +1 more source