Results 51 to 60 of about 347,568 (271)

Scanning for therapeutic targets within the cytokine network of idiopathic inflammatory myopathies [PDF]

open access: yes, 2015
The idiopathic inflammatory myopathies (IIM) constitute a heterogeneous group of chronic disorders that include dermatomyositis (DM), polymyositis (PM), sporadic inclusion body myositis (IBM) and necrotizing autoimmune myopathy (NAM).
De Paepe, Boel, Zschüntzsch, Jana
core   +3 more sources

Clinical and autoantibody phenotypes of juvenile dermatomyositis

open access: yesRheumatology, 2022
Juvenile dermatomyositis (JDM) is a heterogeneous autoimmune inflammatory myositis with symmetrical proximal muscle weakness and a characteristic rash. Juvenile dermatomyositis is characterized by variable presentation and phenotypes.
O. Boyarchuk, Anna Kuka, Iryna Yuryk
semanticscholar   +1 more source

Multi-Modal Single-Cell Sequencing Identifies Cellular Immunophenotypes Associated With Juvenile Dermatomyositis Disease Activity

open access: yesFrontiers in Immunology, 2021
Juvenile dermatomyositis (JDM) is a rare autoimmune condition with insufficient biomarkers and treatments, in part, due to incomplete knowledge of the cell types mediating disease.
J. Neely   +7 more
semanticscholar   +1 more source

Risk factors associated with calcinosis of juvenile dermatomyositis [PDF]

open access: yes, 2008
OBJETIVO: Identificar fatores de risco associados à calcinose em crianças e adolescentes com dermatomiosite juvenil. MÉTODOS: Prontuários de 54 pacientes com dermatomiosite juvenil foram estudados.
AIKAWA, Nádia E.   +6 more
core   +3 more sources

Resolution of calcinosis using bisphosphonates in overlap syndrome – a case report

open access: yesBMC Rheumatology, 2021
Introduction Calcinosis cutis is a common complication of pediatric rheumatologic diseases. However, there is currently no consensus on first-line treatment.
Mitchell Platter   +2 more
doaj   +1 more source

Clues to Disease Activity in Juvenile Dermatomyositis: Neopterin and Other Biomarkers

open access: yesDiagnostics, 2021
Easily accessible biomarkers are urgently needed to evaluate immune activation in Juvenile Dermatomyositis (JDM). The goal of this retrospective study is to define immunological and clinical differences between untreated JDM patients with either normal ...
Amer M. Khojah   +2 more
semanticscholar   +1 more source

Biomarkers in Inflammatory Myopathies – An Expanded Definition [PDF]

open access: yes, 2019
Biomarkers as parameters of pathophysiological conditions can be of outmost relevance for inflammatory myopathies. They are particularly warranted to inform about diagnostic, prognostic, and therapeutic questions.
Benveniste, Olivier   +2 more
core   +2 more sources

Gene Expression Profiles of Treatment Response and Non‐Response in Children With Juvenile Dermatomyositis

open access: yesACR Open Rheumatology, 2022
The study objective was to identify differences in gene expression between treatment responders (TRs) and treatment non‐responders (TNRs) diagnosed with juvenile dermatomyositis (JDM).
C. Stingl   +8 more
semanticscholar   +1 more source

Nuclear matrix protein 2 antibody-positive adult dermatomyositis: a case report and review of the literature [PDF]

open access: yes, 2020
Dermatomyositis is a clinically heterogenous inflammatory myopathy with unique cutaneous features. Myositis-specific antibodies can aid in diagnosis and anticipation of patient prognosis.
Cartron, Alexander M   +3 more
core  

Comparison of the Utility and Validity of Three Scoring Tools to Measure Skin Involvement in Patients With Juvenile Dermatomyositis [PDF]

open access: yes, 2016
OBJECTIVE: To compare the abbreviated Cutaneous Assessment Tool (CAT), Disease Activity Score (DAS), and Myositis Intention to Treat Activity Index (MITAX) and correlate them with the physician's 10-cm skin visual analog scale (VAS) in order to define ...
Almeida, B   +9 more
core   +1 more source

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