Results 41 to 50 of about 3,713 (208)

Juvenile Granulosa Cell Tumors of the Ovary

open access: yesAmerican Journal of Clinical Pathology, 2020
Abstract Objective To explore the clinical and pathologic features of ovarian juvenile granulosa cell tumors (JGCTs). Methods Clinical data, histopathologic observations, immunohistochemical results, FOXL2 mutation status, and follow ...
Yuhong Ye   +6 more
openaire   +2 more sources

Neonatal exposure to xenoestrogens impairs the ovarian response to gonadotropin treatment in lambs [PDF]

open access: yes, 2015
Bisphenol A (BPA) and diethylstilbestrol (DES) are xenoestrogens which have been associated with altered effects on reproduction. We hypothesized that neonatal xenoestrogen exposure affects the ovarian functionality in lambs.
Belmonte, Norberto Miguel   +8 more
core   +2 more sources

The association of enchondromatosis with malignant transformed chondrosarcoma and ovarian juvenile granulosa cell tumor (Ollier disease)

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2017
Objective: Ovarian juvenile granulosa cell tumor has an interesting association with multiple enchondromatosis (Ollier disease and Maffucci syndrome) and should be considered a leading diagnosis when an ovarian mass is found in young patients with these ...
Andrea Burgetova   +8 more
doaj   +1 more source

Three Different Ways to Miss a Granulosa Cell Tumor – A Lesson to be Learne

open access: yesAsian Pacific Journal of Cancer Care, 2021
Granulosa cell tumours (GCTs) account for approximately 70% of malignant sex-cord stromal tumors but are still uncommon and comprise only 2–5% of all ovarian neoplasms. They are classified as adult and juvenile GCTs.
Neethu Puthalon Kunnath   +2 more
doaj   +1 more source

Massive Ascites as the Only Sign of Ovarian Juvenile Granulosa Cell Tumor in an Adolescent: A Case Report and a Review of the Literature

open access: yesCase Reports in Oncological Medicine, 2013
Ovarian neoplasms are relatively rare in childhood and adolescence; only 5% to 8% of the cases are of sex cord stromal origin. Granulosa cell tumors are a group of estrogen producing sex cord stromal tumors of the ovary. They occur in 95% of the cases in
Azin Ashnagar   +4 more
doaj   +1 more source

Effects of an inhibitor of the gamma-secretase complex on proliferation and apoptotic parameters in a FOXL2-mutated granulosa tumor cell line (KGN). [PDF]

open access: yes, 2013
Ovarian granulosa cell tumors (GCTs) represent 3%-5% of all ovarian malignancies. Treatments have limited proven efficacy and biologically targeted treatment is lacking.
Abramovich, Dalhia Nurit   +5 more
core   +2 more sources

HER2 and GATA4 are new prognostic factors for early-stage ovarian granulosa cell tumor-a long-term follow-up study [PDF]

open access: yes, 2014
Peer ...
Andersson, Noora Karoliina   +6 more
core   +1 more source

Sex Reversal in Zebrafish fancl Mutants is Caused by Tp53-Mediated Germ Cell Apoptosis [PDF]

open access: yes, 2013
The molecular genetic mechanisms of sex determination are not known for most vertebrates, including zebrafish. We identified a mutation in the zebrafish fancl gene that causes homozygous mutants to develop as fertile males due to female-to-male sex ...
Asakawa, Kazuhide   +6 more
core   +2 more sources

Follicle stimulating hormone modulates ovarian stem cells through alternately spliced receptor variant FSH-R3 [PDF]

open access: yes, 2013
BACKGROUND: We have earlier reported that follicle stimulating hormone (FSH) modulates ovarian stem cells which include pluripotent, very small embryonic-like stem cells (VSELs) and their immediate descendants ‘progenitors’ termed ovarian germ stem cells
Deepa Bhartiya   +5 more
core   +1 more source

Juvenile granulosa cell tumor presenting as isosexual precocious puberty: A case report and review of literature

open access: yesIndian Journal of Endocrinology and Metabolism, 2013
The differential diagnosis for precocious puberty in a young female includes peripheral causes. This case report documents a rare cause of isosexual precocious puberty, a juvenile granulosa cell tumor of the ovary-and a brief literature review.
Nisha Nigil Haroon   +3 more
doaj   +1 more source

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