Systematic drug sensitivity testing reveals synergistic growth inhibition by dasatinib or mTOR inhibitors with paclitaxel in ovarian granulosa cell tumor cells [PDF]
Objective. Resistance to standard chemotherapy poses a major clinical problem in the treatment of ovarian cancer patients. Adult-type granulosa cell tumor (AGCT) is a unique ovarian cancer subtype for which efficient treatment options are lacking in ...
Aittokallio, Tero +15 more
core +1 more source
Granulosa cell tumor of testis: Clinicopathological correlation of a rare tumor
Background: Granulosa cell tumor of testis is a rare tumor accounting for less than 4% of adult testicular tumors though they account for nearly 30% of childhood testicular tumors.
Swapnil Ulhas Rane +4 more
doaj +1 more source
Juvenile granulosa cell tumor with an unusual immunoprofile, presenting as precocious puberty
Shruti Dogra +3 more
doaj +2 more sources
Functional analysis and transcriptional output of the Göttingen minipig genome [PDF]
In the past decade the Göttingen minipig has gained increasing recognition as animal model in pharmaceutical and safety research because it recapitulates many aspects of human physiology and metabolism.
Badi, Laura +21 more
core +9 more sources
JUVENILE GRANULOSA CELL TUMOR IN A 5 YEARS-OLD BULGARIAN GIRL PRESENTING WITH PRECOCIOUS PUBERTY: A CASE REPORT [PDF]
Ovarian tumors in children before puberty are rare and usually non-malignant. Granulosa cell tumors are rare sex cord-stromal tumors, accounting for 5% of all ovarian tumors and occur mainly in premenarchal girls and in women younger than 30 years.
Diana Hristova +4 more
doaj +1 more source
Clinical management of ovarian small-cell carcinoma of the hypercalcemic type: A proposal for conservative surge [PDF]
Ovarian small-cell carcinoma of the hypercalcemic type is a rare and highly malignant tumor. In two thirds of the patients, the tumor is associated with asymptomatic paraneoplastic hypercalcemia.
Burg, M. (Mirjam) van der +5 more
core +1 more source
Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips
Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck +4 more
wiley +1 more source
Tumor de células da granulosa e gravidez.
Ovary tumor and pregnancy is a rare and serious condition with an unexpected outcome as it can interfere with the course of pregnancy. The authors report a case of a large juvenile granulosa cell tumor diagnosed at 33 weeks of pregnancy during a routine ...
Ana Paula Machado +4 more
doaj +1 more source
Introduction Nasal chondromesenchymal hamartoma (NCMH) is a rare cause of nasal mass in infants and children. It was first described in 1998, and since then, only 63 previous cases have been reported. Case Report Here, we report a case of a 4‐day‐old neonate with a right‐sided nasal mass presenting with respiratory distress since birth.
Mikiyas Olani +6 more
wiley +1 more source
Central precocious puberty and granulosa cell ovarian tumor in an 8-year old female
Ovarian tumors associated with hormonal changes of the peripheral iso-sexual precocious puberty are of common presentation. We describe here a rare case of juvenile granulosa cell tumor in a female with central precocious puberty (CPP).
Valeria Calcaterra +9 more
doaj +1 more source

