Results 81 to 90 of about 3,713 (208)

Premature ovarian failure and ovarian autoimmunity [PDF]

, 1997
Premature ovarian failure (POF) is defined as a syndrome characterized by menopause before the age of 40 yr. The patients suffer from anovulation and hypoestrogenism.
A. Hoek, Aaltonen, Ahonen, Ahonen, Aiman, Allison, Allison, Alper, Alper, Alper, Anasti, Anasti, Atria, Austin, Austyn, Austyn, Austyn, Ayala, Baker, Bannatyne, Batchelor, Bateman, Baumann-Antczak, Behrman, Belvisi, Betterle, Betz, Biddison, Bierer, Biscotti, Blizzard, Block, Blumenfeld, Board, Bohmig, Borst, Bottazzo, Bottazzo, Bottazzo, Brenner, Brenner, Burton, Byrne, Cameron, Campbell, Caux, Chamberlin, Charlton, Chen, Chiauzzi, Colle, Collen, Collins, Cooper, Corenblum, Costoff, Coulam, Coulam, Coulam, Coulam, Coulam, Coulam, Coulam, Cowchock, Dahl, Damewood, Damjanovic, Damjanovic, Day, de Moraes-Ruehsen, de Moraes-Ruehsen, Dean, DeGroot, Dewhurst, Duignan, d’Andrea, Edmonds, Elder, Emperaire, Emperaire, Epplen, Escobar, Falk, Falk, Fitch, Fitzgerald, Flechner, Fraser, Fraser, Freudenthal, Friedman, Friedman Cl Gurgen-Varol, Furmaniak, Germain, Gloor, Golonka, Goodnow, Green, Greenberger, Greiner, Griffin Jr, H. A. Drexhage, Hanafusa, Harding, Hart, Hart, Hart, Heller, Hens, Herberman, Hill, Ho, Ho, Hoek, Hoek, Horning, Inaba, Irvine, Irvine, Ivanova, Iwatani, J. Schoemaker, Jackson, Jackson, Jankovic, Jansen, Jaroudi, Jaszmann, Jeppsson, Jia, Jin, Johnson, Jones, June, Kabel, Kamada, Kamperdijk, Kappler, Kaufman, Kiessling, Kim, Kimura, Kinch, Koninckx, Krailo, Krauss, Krawinkel, Kroemer, Krohn, Kuki, Labarbera, Lanier, Lanier, Le Floch, Leder, Leenen, Leibovich, Linsley, Lonsdale, Lou, Luborsky, Lundberg, Luo, Many, Marazuela, Marrack, Mathur, Mathur, Mattison, Maxson, McNatty, Meeker, Menon, Meuer, Mignot, Mignot, Milgrom, Miller, Miller, Miyake, Miyake, Mohler, Monaco, Moncayo, Moncayo, Moncayo-Naveda, Moore, Morahan, Morrison, Mosmann, Moss, Muechler, Mueller, Muir, Munoz, Munro Neville, Murphy, Myers, Nagler, Neefjes, Nelson, Nelson, Norton, Nossal, Oettgen, Panidis, Parker, Pekonen, Perussia, Philip, Pierce, Plunkett, Podack, Powrie, Prickett, Prinz, Pure, Quill, Rabinowe, Rabinowe, Rabinowe, Rebar, Rebar, Rhim, Rock, Romagnani, Royer, Rudensky AYu Preston-Hulburt, Russell, Sakaguchi, Sakaguchi, Sakaguchi, Sakaguchi, Schreiber, Schwartz, Scott, Seaman, Sedmak, Sele, Serreze, Shangold, Sharf, Shimizu, Singh, Skinner, Sluss, Smith, Smith, Smith, Smith, Song, Sotsiou, Starup, Starup, Steinman, Strominger, Suda, Taguchi, Taguchi, Taguchi, Tang, Tas, Teh, Teunissen, Theofilopoulos, Tilly, Todd, Tonegawa, Townsend, Trinchieri, Trunca, Tsirigotis, Tung, Turkington, Uibo, Uibo, Vakkila, Vallotton, van Dongen, van Ewijk, van Furth, van Voorhis, van Weissenbruch, Velloso, Villanueva, Volpe, Voorbij, Voorbij, Walfish, Walsh, Wardell, Warne Gl Fairley, Waxman, Weetman, Wheatcroft, Whitehead, Wick, Wick, Wick, Williamson, Winqvist, Winqvist, Winqvist, Witmer, Wolfe, Wolffenbuttel, Wood, Wright, Wulffraat, Yamakawa, Yen, Yoon, Yuan, Zarate, Zarate, Zourlas   +315 more
core   +3 more sources

Reproductive and developmental effects of phthalate diesters in females. [PDF]

, 2013
Phthalate diesters, widely used in flexible plastics and consumer products, have become prevalent contaminants in the environment. Human exposure is ubiquitous and higher phthalate metabolite concentrations documented in patients using medications with ...
Chambers, Christina, Foster, Warren G, Kay, Vanessa R   +2 more
core   +1 more source

CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti‐tumoral compounds

Molecular Oncology, Volume 19, Issue 4, Page 1092-1116, April 2025.
FOXL2 c.402C>G mutation drives granulosa cell tumors. Using CRISPR technology, we selectively corrected this mutation, reducing malignancy and increasing sensitivity to dasatinib and ketoconazole. Transcriptomic changes revealed potential therapeutic targets, demonstrating CRISPR's promise for treating this rare ovarian cancer.
Sandra Amarilla‐Quintana, Paloma Navarro, Iván Hernández, Alejandra Ramos, Ana Montero‐Calle, Pablo Cabezas‐Sainz, Maria J Barrero, Diego Megías, Borja Vilaplana‐Martí, Carolina Epifano, Déborah Gómez‐Dominguez, Sara Monzón, Isabel Cuesta, Laura Sánchez, Rodrigo Barderas, Jesús García‐Donas, Alberto Martín, Ignacio Pérez de Castro   +17 more
wiley   +1 more source

Clinical utility of ultrasonography in pediatric and adolescent gynecology: retrospective review of 1313 ultrasound examinations

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 2, Page 226-234, February 2025.
ABSTRACT Objectives Ultrasound is the first‐line imaging modality of the pelvis in the pediatric and adolescent gynecology (PAG) population. Ultrasound findings in pre‐ and postpubertal PAG patients differ from those in adults. Diagnostic models for adnexal pathology have not been validated in this cohort.
N. Cooper, H. Meehan, K. Linton‐Reid, J. Barcroft, J. Danin, M. Seah, S. Sadigh, N. Bharwani, S. Sur, C. Fotopoulou, C. Landolfo, J. Yazbek, S. Saso, D. Timmerman, T. Bourne, M. Al‐Memar   +15 more
wiley   +1 more source

A rare case of ovarian granulosa cell tumour in an adolescent girl with secondary amenorrhea and virilisation [PDF]

, 2017
Sex cord stromal ovarian tumors account for about 5-8% of all ovarian malignancies. Granulosa cell tumor is an   estrogen secreting low grade malignant tumor and is seen in women of all ages with 2% bilaterality. Based upon histology, these neoplasms can
Mehendale, Madhuri, Nayak, Arun, Sarmalkar, Meenal, Shah, Shrutika, Singh, Neha   +4 more
core   +2 more sources

Risk Factors and Clinical Outcomes of Recurrence in Adult Ovarian Granulosa Cell Tumors

Cancer Reports, Volume 7, Issue 10, October 2024.
ABSTRACT Purpose Granulosa cell tumors (GCTs) of the ovary are rare but clinically significant malignancies. Despite advances in treatment, recurrence has remained a substantial challenge. This study aimed to identify clinical outcomes and potential prognostic risk factors for recurrence in patients diagnosed with GCTs.
Mansoureh Golmohammadi Tavallaee, Malihe Hasanzadeh Mofrad, Zohreh Yousefi, Mansoureh Mottaghi, Fatemeh Homaei Shandiz, Behrouz Davachi, Bahram Hamidi, Marjaneh Farazestanian, Fahimeh Afzaljavan   +8 more
wiley   +1 more source

Virilization and abdominal mass in a newborn female: A case report

Journal of Pediatric Surgery Case Reports, 2017
We describe virilization in a newborn female secondary to bilateral congenital juvenile granulosa cell tumor (JGCT). The patient presented with abdominal mass and ambiguous genitalia at birth, and bilateral ovarian masses were discovered on further ...
Natalie A. Drucker, MD, Brian W. Gray, MD, Johanna Askegard-Giesmann, MD   +2 more
doaj   +1 more source

A case of ovarian juvenile granulosa cells tumor with peritoneal and jejunal localisation at Amath Dansokho Regional Hospital, Kedougou, Senegal [PDF]

Granulosa tumors are rare ovarian tumors they belong to sex-cord and stromal tumor family. They are the most common type of malignant stromal tumor and have a good prognosis.
Diallo, Thierno A. T., Diop, Ousmane, Faye, Khadim, Keita, Abdoulaye, Konate, Nankouma, Sane, Doudou, Sarr, Alfred N., Tandian, Foulaké, Wade, Mouhamadou   +8 more
core   +2 more sources

Update of the scientific opinion on tetrabromobisphenol A (TBBPA) and its derivatives in food

EFSA Journal, Volume 22, Issue 7, July 2024.
Abstract The European Commission asked EFSA to update its 2011 risk assessment on tetrabromobisphenol A (TBBPA) and five derivatives in food. Neurotoxicity and carcinogenicity were considered as the critical effects of TBBPA in rodent studies. The available evidence indicates that the carcinogenicity of TBBPA occurs via non‐genotoxic mechanisms. Taking
EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Heather Wallace, Diane Benford, Andy Hart, Henri Schroeder, Martin Rose, Martine Vrijheid, Eirini Kouloura, Luisa Ramos Bordajandi, Francesca Riolo, Christiane Vleminckx   +25 more
wiley   +1 more source

Juvenile granulosa cell tumor of the ovary in a 7-year-old girl: Rare case report

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2020
Ovarian granulosa cell tumor (GCT) is a rare ovarian neoplasm, which typically occurs in children and young women. More than 90% of the patients are diagnosed in Stage IA, who can be cured by unilateral oophorectomy. Meanwhile, the remaining is diagnosed
Aditya Pratap Singh, Arun Kumar Gupta, Arpita Jindal, Maryem Ansari   +3 more
doaj   +1 more source