Results 61 to 70 of about 91,965 (229)

Cortical and Striatal Circuits in Huntington's Disease

, 2020
Huntington's disease (HD) is a hereditary neurodegenerative disorder that typically manifests in midlife with motor, cognitive, and/or psychiatric symptoms.
Blumenstock, S., Dudanova, I.
core   +1 more source

Molecular diagnosis of Huntington disease in Portugal : implications for genetic counselling and clinical practice [PDF]

, 2003
Huntington disease (HD) is a eurodegenerative, autosomal dominant disorder of late-onset, caused by the expansion of a CAG repeat in the coding region of the gene. Ours is the reference laboratory for genetic testing in HD, in Portugal, since 1998; 90.1%
A Durr, Alda Sousa, B Kremer, Carolina Garrett, CM James, Cristina Januário, D Craufurd, D Falush, DGR Evans, EW Almqvist, Fernando Regateiro, Fátima Ferreirinha, Isabel Gaspar, J Sambrook, JB Martin, Jorge Sequeiros, José Vale, Laura Guimarães, Leal Loureiro, M Guida, M Losekoot, Maria do Carmo Costa, Marina Magalhães, MR Hayden, Patrícia Maciel, Paula Magalhães, PS Harper, PS Harper, RC Moore, RG Snell, RH Myers, S Siesling, SA Simpson, SE Andrew, SE Andrew, SE Andrew, SE Andrew, SE Holmes, YP Goldberg, YP Goldberg   +39 more
core   +1 more source

Psychogenic non-epileptic seizures in early Huntington's disease [PDF]

, 2016
Huntington's disease (HD) is a neurodegenerative condition characterised by motor dysfunction with involuntary movements and loss of voluntary control, cognitive deterioration and psychiatric problems.
Rodrigues, FB, Wild, EJ
core   +1 more source

“Ectopic” theta oscillations and interictal activity during slow-wave state in the R6/1 mouse model of Huntington's disease

Neurobiology of Disease, 2012
The pathophysiology of Huntington's disease (HD) is primarily associated with striatal degeneration and a number of behavioral symptoms such as involuntary movements, cognitive decline, psychiatric disorders, and in the most juvenile-onset cases with ...
Michele Pignatelli, Fanny Lebreton, Yoon H. Cho, Xavier Leinekugel   +3 more
doaj   +1 more source

Huntington\u27s Disease--A Review [PDF]

, 2016
Huntington’s disease is degenerative and effects both cognitive and motor functioning, beginning in the 20s and continuing a decline for about two decades until death.
Dunn, Christen
core   +1 more source

Progression of motor subtypes in Huntington’s disease. a 6-year follow-up study [PDF]

, 2016
The objective of this study is to investigate the progression of predominantly choreatic and hypokinetic-rigid signs in Huntington's disease (HD) and their relationship with cognitive and general functioning over time.
Bentivoglio, A. R., Burgunder, J. M., Craufurd, D., Ferraldeschi, Michela, Hart, E. P., Jacobs, M, Reilmann, R., Ristori, Giovanni, Romano, Silvia, Roos, R. A. C., Saft, C., The REGISTRY, investigators of the European Huntington’s Disease Network, van Zwet, E. W.   +12 more
core   +2 more sources

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

A survey-based study identifies common but unrecognized symptoms in a large series of juvenile Huntington's disease.

Neurodegenerative Disease Management, 2017
AIM The symptoms of Huntington's disease are well known, yet the symptoms of juvenile Huntington's disease (JHD) are less established due to its rarity.
A. Moser, E. Epping, P. Espe-Pfeifer, Erin Martin, L. Zhorne, K. Mathews, M. Nance, Denise Hudgell, O. Quarrell, P. Nopoulos   +9 more
semanticscholar   +1 more source

Radiotherapy Side Effects: Comprehensive Proteomic Study Unraveled Neural Stem Cell Degenerative Differentiation upon Ionizing Radiation

Biomolecules, 2022
Cranial radiation therapy is one of the most effective treatments for childhood brain cancers. Despite the ameliorated survival rate of juvenile patients, radiation exposure-induced brain neurogenic region injury could markedly impair patients’ cognitive
Dong Liang, Meng Ning, Hang Xie, Xiaoyan He, Peigen Ren, Xiaohua Lei, Xuepei Zhang   +6 more
doaj   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source