Results 41 to 50 of about 91,965 (229)
The differential diagnosis of chorea [PDF]
, 2007 Chorea is a hyperkinetic movement disorder characterised by excessive spontaneous movements that are irregularly timed, randomly distributed and abrupt. In this article, the authors discuss the causes of chorea, particularly Huntington's disease and the ...
Tabrizi, SJ, Wild, EJ
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Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis [PDF]
, 2013 Although mutations in the huntingtin gene (HTT) due to poly-Q expansion cause neuropathology in humans (Huntington's disease; HD), the normal function(s) of the gene and its protein (HTT) remain obscure.
Brown, Euan R. +2 more
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Subcortical T1-Rho MRI Abnormalities in Juvenile-Onset Huntington’s Disease
Brain Sciences, 2020 Huntington’s disease (HD) is a fatal neurodegenerative disease caused by the expansion of cytosine-adenine-guanine (CAG) repeats in the huntingtin gene. An increased CAG repeat length is associated with an earlier disease onset.
Alexander V. Tereshchenko +6 more
doaj +1 more source
The Association between CAG Repeat Length and Age of Onset of Juvenile-Onset Huntington’s Disease
Brain Sciences, 2020 There is a known negative association between cytosine–adenine–guanine (CAG) repeat length and the age of motor onset (AMO) in adult-onset Huntington’s Disease (AOHD).
Jordan L. Schultz +2 more
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Abnormal Weight and Body Mass Index in Children with Juvenile Huntington's Disease. [PDF]
J Huntingtons Dis, 2015 Background and objectives: The hallmark clinical manifestation of Huntington’s disease (HD), namely lower weight and BMI has been reported in prodromal HD (PreHD) adults and also in PreHD children.
Tereshchenko A +6 more
europepmc +2 more sources
Stem Cell Research, 2023 Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by an abnormal length of CAG repeats in the gene HTT, leading to an elongated poly-glutamine (poly-Q) sequence in huntingtin (HTT).
Duncan C. Miller +6 more
doaj +1 more source
Sphingomyelin and GM1 Influence Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes [PDF]
, 2018 Huntington disease (HD) is an inherited neurodegenerative disease caused by the expansion beyond a critical threshold of a polyglutamine (polyQ) tract near the N-terminus of the huntingtin (htt) protein. Expanded polyQ promotes the formation of a variety
Campbell, Warren A. +5 more
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Pediatric Neurology Briefs, 1989 The positron-emission tomography (PET) findings in a seven year old girl with the juvenile form of Huntington's disease are described from the Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, Montreal, Canada.
J Gordon Millichap
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Nutritional management of individuals with Huntington’s disease: nutritional guidelines [PDF]
, 2012 The delivery of good nutritional care is a fundamental element of the management of individuals with Huntington’s disease and all patients with Huntington’s disease will, at some time, need dietary intervention because of the sequela of the disease; yet ...
Brotherton, Ailsa M +5 more
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Juvenile Huntington’s disease in northern Brazil: a case series report
Revista de Ciências Médicas e Biológicas, 2022 Introduction: Huntington’s disease (HD) is a neurodegenerative disorder caused by CAG expansion repeats in the HTT gene. Usually, the symptoms start to manifest in mid-adulthood.
Diana Vieira Brito +4 more
semanticscholar +1 more source