Results 61 to 70 of about 53,251 (224)

СONCENTRATION OF ANTI-INFLAMATORY CYTOKINES IN CELL CULTURE SUPERNATANTS IN CHILDREN WITH JUVENILE IDIOPATHIC ARTHRITIS

Медицинская иммунология, 2019
Juvenile idiopathic arthritis is a chronic inflammatory disease of the joints in children, mainly of autoimmune or auto-inflammatory nature. It is a heterogeneous group, which includes different subtypes of the disease. Different mechanisms may play role
I. M. Krivolapova, I. A. Pashnina, V. A. Chereshnev   +2 more
doaj   +1 more source

Development and Role in Therapy of Canakinumab in Adult-Onset Still's Disease [PDF]

, 2018
Adult-onset Still's disease (AOSD) is a rare inflammatory disease of unknown etiology typically characterized by episodes of spiking fever, evanescent rash, arthralgia, leukocytosis, and hyperferritinemia. The pivotal role of interleukin (IL)-1 and other
Baggio, Chiara, Bindoli, S, Galozzi, P, Oliviero, F, Sfriso, P   +4 more
core   +1 more source

Single‐Cell RNA Sequencing Informs Precision Targeting of Monogenic Lupus Associated With IKZF1 Haploinsufficiency

Arthritis &Rheumatology, EarlyView.
Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently known genetic mutations, and healthy controls were analyzed using single‐cell
Qi Zheng, Yejun Tan, Zhaoling Wang, Yanjie Qian, Qian Ma, Danping Shen, Meiping Lu   +6 more
wiley   +1 more source

CLINICAL CASE OF TOCILIZUMAB USE IN A PATIENT WITH SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS

Педиатрическая фармакология, 2014
The article presents a case of successful use of a preparation of monoclonal antibodies to interleukin 6 receptors (tocilizumab) at asevere systemic juvenile idiopathic arthritis.
O. L. Lomakina, E. I. Alexeyeva, R. V. Denisova, T. V. Sleptsova, A. N. Fetisova   +4 more
doaj   +1 more source

Interleukin‐18 Levels Are Associated With Disease Course in Patients With Still Disease Treated With Interleukin‐1 Inhibitors

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the prognostic utility of circulating interleukin‐18 (IL‐18) levels in predicting disease activity, macrophage activation syndrome (MAS), and disease course in patients with Still disease (SD) receiving first‐line IL‐1 inhibitors (IL‐1i).
Matteo Trevisan, Manuela Pardeo, Ivan Caiello, Claudia Bracaglia, Arianna De Matteis, Valentina Matteo, Elena Loricchio, Fabrizio De Benedetti, Giusi Prencipe   +8 more
wiley   +1 more source

Imaging of juvenile idiopathic arthritis. Part I: Clinical classifications and radiographs [PDF]

Journal of Ultrasonography, 2016
Juvenile idiopathic arthritis is the most common autoimmune systemic disease of the connective tissue affecting individuals at the developmental age. Radiography is the primary modality employed in the diagnostic imaging in order to identify changes ...
Iwona Sudoł-Szopińska, Genowefa Matuszewska, Piotr Gietka, Mateusz Płaza, Marta Walentowska-Janowicz   +4 more
doaj   +1 more source

One year in review: ultrasound in arthritis [PDF]

, 2016
Musculoskeletal ultrasound (MSUS) has become a relevant part of rheumatology practice and research because it substantially allows us to optimize management of rheumatic and musculoskeletal diseases. This non-invasive imaging modality is a valuable point-
IAGNOCCO, Annamaria, Naredo, Esperanza
core  

Rehabilitation in juvenile idiopathic arthritis [PDF]

, 2007
INTRODUCTION AND AIMS: juvenile idiopathic arthritis (JIA) may cause permanent physical disabilities in children and adolescents. This study aimed to describe the several kinds of rehabilitation procedures, ranging from evaluation to prescription of ...
Azevedo, Mariana Moreira Alckmin [UNIFESP], Bueno, Vanessa Cristina [UNIFESP], Hilário, Maria Odete Esteves [UNIFESP], Len, Claudio Arnaldo [UNIFESP], Lombardi Júnior, Imperio [UNIFESP], Medeiros, Wladimir Musetti [UNIFESP], Natour, Jamil [UNIFESP], Terreri, Maria Teresa Ramos Ascensão [UNIFESP]   +7 more
core   +2 more sources

Measuring the Impact: Magnetic Resonance Imaging Response of Sacroiliac Joints to Tumor Necrosis Factor Inhibitors in Youth With Axial Disease

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes (PROs) in youth with axial juvenile spondyloarthritis (axJSpA) initiating tumor necrosis factor inhibitor (TNFi).
Timothy G. Brandon, Rui Xiao, Daniel J. Lovell, Edward Oberle, Matthew L. Stoll, Nancy A. Chauvin, Michael L. Francavilla, Walter P. Maksymowych, Pamela F. Weiss   +8 more
wiley   +1 more source

Temporomandibular joint disorders as the only manifestation of juvenile idiopathic arthritis: a case report

Einstein (São Paulo)
Juvenile idiopathic arthritis is a term used to include all chronic childhood arthritis of unknown etiology. It is characterized by chronic inflammation persisting for at least 6 weeks, beginning before 16 years of age.
José Renato Ribeiro Pinto, Irineu Gregnanin Pedron, Estevam Rubens Utumi, Milton Edson Miranda, Elisa Cruz Pereira Pinto, Leopoldo Penteado Nucci   +5 more
doaj   +1 more source