Connective tissue nevus misdiagnosed as juvenile localized scleroderma [PDF]
Pediatric Rheumatology Online Journal, 2023 Background Connective tissue nevi (CTN) are congenital hamartomas caused by excessive proliferation of dermis components. In children, CTN can mimic juvenile localized scleroderma (JLS), an immune mediated skin disorder that requires aggressive ...
F. Tirelli +7 more
doaj +9 more sources
Mycophenolate mofetil for methotrexate-resistant juvenile localized scleroderma. [PDF]
Rheumatology (Oxford), 2021 Objectives To investigate safety and efficacy of MMF in patients with severe or MTX-refractory juvenile localized scleroderma. Methods Consecutive juvenile localized scleroderma patients undergoing systemic treatment were included in a retrospective ...
Martini G +5 more
europepmc +9 more sources
Juvenile localized scleroderma: review of 44 patients [PDF]
Pediatric Rheumatology Online Journal, 2011 Predominant form of childhood sclerosis is localized scleroderma (LSc) or morphoea. Preliminary classification includes circumscribed morphoea (CM), linear scleroderma (LS), generalized (GM), panclerotic (PM) and mixed morphoea (MM). The major problem in untreated patients is morbidity, so the aim of the therapy is to prevent this.
Iglesias E +7 more
doaj +11 more sources
Juvenile localized scleroderma: a large retrospective cohort study from a tertiary care center [PDF]
Pediatric Rheumatology Online JournalBackground Juvenile localized scleroderma is a rare pediatric inflammatory disease that primarily affects the skin and subcutaneous tissue but also has the potential to impact deeper tissues and can be associated with extracutaneous manifestations ...
Bugra Han Egeli +8 more
doaj +5 more sources
Baseline Description of the Juvenile Localized Scleroderma Subgroup From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry [PDF]
ACR Open Rheumatology, 2019 Objective Localized scleroderma (LS) is a chronic inflammatory and fibrosing skin disorder. We present baseline data on the juvenile LS (jLS) cohort from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry, a multicenter ...
Eveline Y. Wu +6 more
doaj +4 more sources
Juvenile Localized Scleroderma with Hyaline Deposits in the Renal Arteriole [PDF]
Case Reports in Dermatology, 2018 We report a 10-year-old boy with localized scleroderma of the linear and plaque type, who showed proteinuria and hematuria. In this patient, skin, articular, and renal manifestations appeared successively and then began to resolve in the same order.
Nobuko Tabata, Chiyoko Nagano Inoue
doaj +6 more sources
Reliability of LoSCAT score for activity and tissue damage assessment in a large cohort of patients with Juvenile Localized Scleroderma [PDF]
Pediatric Rheumatology Online Journal, 2018 Objectives To assess reliability of the two indexes of Localized Scleroderma Cutaneous Assessment Tool (LoSCAT), the modified Localized Scleroderma Skin Severity Index (mLoSSI) and the Localized Scleroderma Skin Damage Index (LoSDI), when applied by ...
Anna Agazzi +4 more
doaj +5 more sources
Long-term methotrexate efficacy in juvenile localized scleroderma [PDF]
Pediatric Rheumatology Online Journal, 2011 Methods We prospectively followed a cohort of patients with JLS who were enrolled in a double-blind, randomized controlled trial. Oral MTX was used at a dose of 15 mg/m once a week (max 20 mg) for at lest 24 months; prednisone (1 mg/Kg/day, max 50 mg), in a single morning dose for 3 months was added.
Giuliotto S +5 more
doaj +12 more sources
Evaluation of autologous fat grafting in the treatment of juvenile localized scleroderma with facial involvement. [PDF]
J Scleroderma Relat DisordObjectives: The objective of this study was to evaluate the effect of autologous fat grafting in patients with juvenile localized scleroderma with facial involvement.
Sander L +5 more
europepmc +4 more sources
Zdorovʹe Rebenka, 2019 Among rheumatic diseases in children, a special place belongs to juvenile localized scleroderma, which is highlighted as a separate form in the structure of scleroderma diseases and is characterized by: the onset of the disease up to 16 years, skin ...
L.F. Bogmat, V.V. Nikonova
doaj +4 more sources