Connective tissue nevus misdiagnosed as juvenile localized scleroderma [PDF]
Pediatric Rheumatology Online Journal, 2023 Background Connective tissue nevi (CTN) are congenital hamartomas caused by excessive proliferation of dermis components. In children, CTN can mimic juvenile localized scleroderma (JLS), an immune mediated skin disorder that requires aggressive ...
F. Tirelli +7 more
doaj +8 more sources
Mycophenolate mofetil for methotrexate-resistant juvenile localized scleroderma. [PDF]
Rheumatology (Oxford), 2021 Objectives To investigate safety and efficacy of MMF in patients with severe or MTX-refractory juvenile localized scleroderma. Methods Consecutive juvenile localized scleroderma patients undergoing systemic treatment were included in a retrospective ...
Martini G +5 more
europepmc +10 more sources
Juvenile localized scleroderma: review of 44 patients [PDF]
Pediatric Rheumatology Online Journal, 2011 Predominant form of childhood sclerosis is localized scleroderma (LSc) or morphoea. Preliminary classification includes circumscribed morphoea (CM), linear scleroderma (LS), generalized (GM), panclerotic (PM) and mixed morphoea (MM). The major problem in untreated patients is morbidity, so the aim of the therapy is to prevent this.
Iglesias E +7 more
doaj +12 more sources
Barriers to care in juvenile localized and systemic scleroderma: an exploratory survey study of caregivers’ perspectives [PDF]
Pediatric Rheumatology Online Journal, 2023 Background Juvenile localized scleroderma (LS) and systemic sclerosis (SSc) are rare pediatric conditions often associated with severe morbidities. Delays in diagnosis are common, increasing the risk for permanent damage and worse outcomes.
Leigh A. Stubbs +20 more
doaj +8 more sources
Juvenile localized scleroderma: a large retrospective cohort study from a tertiary care center [PDF]
Pediatric Rheumatology Online JournalBackground Juvenile localized scleroderma is a rare pediatric inflammatory disease that primarily affects the skin and subcutaneous tissue but also has the potential to impact deeper tissues and can be associated with extracutaneous manifestations ...
Bugra Han Egeli +8 more
doaj +4 more sources
Baseline Description of the Juvenile Localized Scleroderma Subgroup From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry [PDF]
ACR Open Rheumatology, 2019 Objective Localized scleroderma (LS) is a chronic inflammatory and fibrosing skin disorder. We present baseline data on the juvenile LS (jLS) cohort from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry, a multicenter ...
Eveline Y. Wu +6 more
doaj +5 more sources
Juvenile Localized Scleroderma. Questions of Treatment
Вопросы современной педиатрии, 2020 Juvenile localized scleroderma (JLS) is a group of childhood diseases with the main symptom — skin and subcutaneous structures lesions, without any organ involvement. There is active (inflammatory) and fibrotic phase in development of JLS.
Rinat K. Raupov, Mikhail M. Kostik
doaj +5 more sources
Reliability of LoSCAT score for activity and tissue damage assessment in a large cohort of patients with Juvenile Localized Scleroderma [PDF]
Pediatric Rheumatology Online Journal, 2018 Objectives To assess reliability of the two indexes of Localized Scleroderma Cutaneous Assessment Tool (LoSCAT), the modified Localized Scleroderma Skin Severity Index (mLoSSI) and the Localized Scleroderma Skin Damage Index (LoSDI), when applied by ...
Anna Agazzi +4 more
doaj +5 more sources
Juvenile Localized Scleroderma with Hyaline Deposits in the Renal Arteriole [PDF]
Case Reports in Dermatology, 2018 We report a 10-year-old boy with localized scleroderma of the linear and plaque type, who showed proteinuria and hematuria. In this patient, skin, articular, and renal manifestations appeared successively and then began to resolve in the same order.
Nobuko Tabata, Chiyoko Nagano Inoue
doaj +6 more sources
Developing comparative effectiveness studies for a rare, understudied pediatric disease: lessons learned from the CARRA juvenile localized scleroderma consensus treatment plan pilot study [PDF]
Pediatric Rheumatology Online Journal, 2019 Background We designed and initiated a pilot comparative effectiveness study for juvenile localized scleroderma (jLS), for which there is limited evidence on best therapy.
Suzanne C. Li +17 more
doaj +3 more sources