Results 31 to 40 of about 10,033 (195)

Esophageal abnormalities in juvenile localized scleroderma: is it associated with other extracutaneous manifestations?

Revista Brasileira de Reumatologia, 2016
Objective: To assess esophageal involvement (EI) in juvenile localized scleroderma (JLS) population and the possible association between this gastrointestinal manifestation and demographic data, clinical features, laboratory exams, treatments and ...
Clarissa C.M. Valões, Glaucia V. Novak, Juliana B. Brunelli, Katia T. Kozu, Ricardo K. Toma, Clovis A. Silva   +5 more
doaj   +2 more sources

Juvenile Localized Scleroderma from the Perspective of Pediatric Rheumatologist. Aspects of Diagnostics

Вопросы современной педиатрии, 2020
The localized scleroderma (morphea) is the clinical option of the juvenile scleroderma, the third in prevalence rheumatic condition in pediatrics. The article summarizes all the data on the classification, diagnostics, and differential diagnosis of ...
Rinat K. Raupov, Artur I. Imelbaev, Mikhail M. Kostik   +2 more
doaj   +3 more sources

Revealing Microvascular Involvement in Pediatric Localized Scleroderma Through Nailfold Capillaroscopy [PDF]

Children
Background/Objectives: Juvenile localized scleroderma (jLoS) is a chronic inflammatory disorder with skin and subcutaneous tissue involvement. Microvascular alterations are thought to contribute to its pathogenesis.
Sema Nur Taşkın, Şeyda Doğantan, Esra Esen, Sümeyra Özdemir Çiçek, Ayşenur Paç Kısaarslan, Muammer Hakan Poyrazoğlu   +5 more
doaj   +2 more sources

New Challenging Systemic Therapies for Juvenile Scleroderma: A Comprehensive Review [PDF]

Pharmaceuticals
Background: Juvenile scleroderma (JS) comprises a group of rare chronic autoimmune and fibrosing disorders in children, primarily presenting as juvenile localized scleroderma (jLS) or juvenile systemic sclerosis (jSS). While jLS predominantly affects the
Chiara Sassetti, Claudia Borrelli, Martha Mazuy, Cristina Guerriero, Donato Rigante, Susanna Esposito   +5 more
doaj   +2 more sources

Application of integrated traditional Chinese and Western medicine in the treatment of juvenile localized scleroderma with skin ulcer: a case report

Clinical Research Communications, 2023
Background: Juvenile Localized Scleroderma (JLS) is a rare pediatric rheumatic disease characterized by inflammation and skin sclerosis. The side effect of consensus-recommended medications and the risk of disability posed challenges to the JLS treatment.
Jiaqian Zhang, Xiaohan Wang, Wen-Zhen Tu, Liming Chen, Qi Kong, Yin-Huan Zhao   +5 more
openalex   +2 more sources

Ultrasonographic Evaluation of Juvenile Localized Scleroderma: EnhancingObjectivity in Diagnosis and Management

Current medical imaging
BACKGROUND Although clinical assessment has historically been the primary method used for pediatric localized sclerosis (LS) diagnosis and staging, highfrequency ultrasonography (HFUS) is being investigated as a more accurate evaluation method for lesion.
Şeyma Türkmen, Gülşah Pirim, Betül Sözeri   +2 more
openalex   +2 more sources

Endpoints and outcomes for localized scleroderma/morphea: a scoping literature review [PDF]

Pediatric Rheumatology Online Journal
Background Current treatment for localized scleroderma (LS) has been shown to halt disease activity, but little is still known about patient experiences with these treatments, nor is there consensus about optimal measurement strategies for future ...
Alexy Hernandez, Leslie Zapata Leiva, Maria Mutka, Kathryn S. Torok, Leila Ledbetter, Christina K. Zigler   +5 more
doaj   +2 more sources

3233 Von Willebrand Factor is Localized in the Extravascular tissue of Patients with Juvenile Scleroderma [PDF]

Journal of Clinical and Translational Science, 2019
OBJECTIVES/SPECIFIC AIMS: To further explore the role of vWF in the pathogenesis of scleroderma by identifying its location within the tissue of sample biopsies obtained as part of routine diagnosis with the use of immuno-histochemical staining.
Natalia Vasquez Canizares, Morayma Reyes Gil, Dawn M. Wahezi, Beamon Agarwal, Tamar Rubinstein   +4 more
doaj   +2 more sources

CO:06:2 | Deep immunophenotyping in patients with juvenile localized scleroderma reveals two distinct immunological endophenotypes

Reumatismo
Background. The aim of this project is to perform immunophenotyping of patients with JLS and healthy controls to assess dysregulated immunological pathways in JLS, and to identify biomarkers able to predict clinical features.   Methods.
Società Italiana di Reumatologia
doaj   +2 more sources

Juvenile Localized Scleroderma

, 2016
Francesco Zulian, Roberta Culpo
openalex   +2 more sources