The frequency of pulmonary hypertension in patients with juvenile scleroderma
Biomolecules & Biomedicine, 2015 Juvenile scleroderma (JS) represents a rarely seen group of connective tissue diseases with multiple organ involvement. Cardiac involvement in JSS is well known and, although rare in children, it may be an important cause of mortality and morbidity ...
Amra Adrovic +7 more
doaj +1 more source
Clinical significance of anti-NOR90 antibodies in systemic sclerosis and idiopathic interstitial pneumonia [PDF]
, 2022 Objective: Anti-NOR90 antibodies are usually found in patients with SSc; however, their clinical relevance remains obscure. We developed an ELISA for measuring them to investigate the clinical features of patients with anti-NOR90 antibodies.
Akiyama, Masashi +6 more
core +1 more source
Prior elicitation of the efficacy and tolerability of Methotrexate and Mycophenolate Mofetil in Juvenile Localised Scleroderma [version 1; peer review: 2 approved] [PDF]
, 2021 Background: Evidence is lacking for safe and effective treatments for juvenile localised scleroderma (JLS). Methotrexate (MTX) is commonly used first line and mycophenolate mofetil (MMF) second line, despite a limited evidence base. A head to head trial
Anderson, Marina E +20 more
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Narrowing Down Key Players in Autoimmunity via Single‐Cell Multiomics
European Journal of Immunology, Volume 55, Issue 6, June 2025.This review explores how single‐cell sequencing and multiomics reveal cell states and communication networks involved in autoimmunity. We highlight insights into antigen specificity and autoreactive lymphocytes, uncovering mechanisms like molecular mimicry.
Altea Gjurgjaj, Cecilia Domínguez Conde
wiley +1 more source
Juvenile diabetes and systemic sclerosis: just a coincidence? [PDF]
, 2022 Background: Limited joint mobility (LJM), previously known as cheiroarthropathy, refers to the presence of reduced extension at the finger joints in people with diabetes and may be associated with scleroderma-like syndromes such as diabetic sclerodactyly.
Martini G. +4 more
core +1 more source
Consensus-based recommendations for the management of juvenile localised scleroderma [PDF]
, 2019 In 2012, a European initiative called Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) was launched to optimise and disseminate diagnostic and management regimens in Europe for children and young adults with rheumatic diseases ...
Anton, Jordi +18 more
core +4 more sources
Optimal management strategies for paediatric morphea – insights from a case series
Pediatria PolskaJuvenile localized scleroderma, or morphea, is a rare chronic inflammatory disease primarily affecting the skin and subcutaneous tissue. Treatment options for paediatric cases are diverse, with a lack of standardised guidelines.
Kinga Łagosz +6 more
doaj +1 more source
The Interconnected World of Dermatology and Ophthalmology
JEADV Clinical Practice, Volume 4, Issue 2, Page 389-399, June 2025.Medical science, is an integrated field that shares intricate relationship between various organ systems. Similarly, dermatology is inter‐related with various other specialties including ophthalmology. This article depicts the correlation of ophthalmology and dermatology iterating on the genetic diseases, autoimmune diseases, systemic disorders ...
Gyanesh Rathore +4 more
wiley +1 more source
How I explore ... the skin functional involvement in scleroderma [PDF]
, 2013 peer reviewedScleroderma refers to distinct clinical presentations sharing in common a sclerotic process most often clinically obvious on the skin. The involvement possibly affects the skin alone in morphea or in combination with internal lesions in ...
Andre, B. +6 more
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