Problems of systemic connective tissue diseases of childhood in historical perspective
The relevance of study systemic connective tissue diseases with juvenile onset for modern medicine is determined by the trend towards their growth in the population, the difficulty of early diagnosis, the rapid development of disability and a poor life ...
M. I. Kaleda, I. P. Nikishina
doaj +1 more source
Geographical Clustering of Juvenile Onset Systemic Lupus Erythematosus within the Sultanate of Oman
Objective: While SLE is found worldwide, there is diversity in clinical presentation of the disease according to geographical variations. The aim of this study is to describe geographical distributions of childhood onset SLE within Oman to identify ...
Ibrahim Al-Zakwani +3 more
doaj +1 more source
Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study [PDF]
Juvenile rheumatoid arthritis (JRA) comprises a group of chronic systemic inflammatory disorders that primarily affect joints and can cause long-term disability.
Woo, P +9 more
core
Kawasaki disease and juvenile systemic lupus erythematosus
Kawasaki disease (KD) is a common vasculitis in childhood. To the authors' knowledge, only one case of juvenile systemic lupus erythematosus (JSLE)-like onset mimicking KD and another case of KD and JSLE association have previously been described ...
Almeida, R. T. +5 more
core +1 more source
Antiphospholipid Syndrome: Expanding the Spectrum of Autoimmune Thrombosis [PDF]
[eng] The antiphospholipid syndrome (APS) is an acquired prothrombotic syndrome characterized by venous or arterial thromboses and pregnancy morbidity.
Gómez-Puerta, José Alfredo
core +2 more sources
Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid syndrome [PDF]
Objective: Previous studies have shown the importance of somatic mutations and arginine residues in the complementarity-determining regions (CDRs) of pathogenic anti-double-stranded DNA (anti-dsDNA) antibodies in human and murine lupus, and in studies of
Yiannis Ioannou +15 more
core +1 more source
Cutaneous manifestations of juvenile onset lupus erythematosus: A clinical study
Introduction: Juvenile-onset systemic lupus erythematosus (SLE) is one of the most common systemic autoimmune connective tissue disorders in children.
Vinitha Panicker +5 more
doaj +1 more source
Management of systemic lupus erythematosus during pregnancy: challenges and solutions [PDF]
Caroline L Knight, Catherine Nelson-Piercy Division of Women’s Health, Women’s Health Academic Centre, King’s College London and King’s Health Partners, St Thomas’ Hospital, London, UK Abstract: Systemic lupus ...
Knight CL +5 more
core +1 more source
Background Proteinuria is a well-known risk factor for progression of renal dysfunction in a variety of chronic kidney diseases. In adult-onset Systemic Lupus Erytematosus (SLE) patients with lupus nephritis (LN), proteinuria takes a significant period ...
Eve M. D. Smith +4 more
doaj +1 more source
Cytokines in relation to autoantibodies before onset of symptoms for systemic lupus erythematosus
Objectives: A number of cytokines and chemokines were analysed and related to autoantibodies in blood samples pre-dating the onset of symptoms of systemic lupus erythematosus.
Eriksson, Catharina, +1 more
core +1 more source

