Results 61 to 70 of about 16,783,451 (339)
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Stability of generalized quadratic functional equation on a set of measure zero
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2015 In this paper we prove the Hyers-Ulam stability of the following K-quadratic functional equation ∑ k ∈ K f(x+ k.y)= Lf(x)+ Lf(y), x,y ∈ E, where E is a real (or complex) vector space.
Youssef Aribou +3 more
doaj +1 more source
K+ Block Is the Mechanism of Functional Asymmetry in Bacterial Na(v) Channels. [PDF]
PLoS Computational Biology, 2016 Crystal structures of several bacterial Na(v) channels have been recently published and molecular dynamics simulations of ion permeation through these channels are consistent with many electrophysiological properties of eukaryotic channels.
Van Ngo +4 more
doaj +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Specialized functional diversity and interactions of the Na,K-ATPase
Frontiers in Physiology, 2016 Na,K-ATPase is a protein ubiquitously expressed in the plasma membrane of all animal cells and vitally essential for their functions. A specialized functional diversity of the Na,K-ATPase isozymes is provided by molecular heterogeneity, distinct ...
Igor I. Krivoi, Vladimir V. Matchkov
doaj +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Band Depth based initialization of $k$-Means for functional data clustering [PDF]
, 2021 Javier Albert-Smet +2 more
openalex +1 more source
The K function and its related statistics have been an enduring tool in the analysis of spatial point processes, providing an easy to compute and interpret summary statistic for characterising the interactions between points of one type, or between two different types of points.
Grainger, Jake P. +3 more
openaire +2 more sources