Results 61 to 70 of about 11,041,440 (317)

k-NN Regression on Functional Data with Incomplete Observations

open access: yes, 2018
In this paper we study a general version of regression where each covariate itself is a functional data such as distributions or functions. In real applications, however, typically we do not have direct access to such data; instead only some noisy ...
Sashank J. Reddi (5363975)   +1 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Stability of generalized quadratic functional equation on a set of measure zero

open access: yesAnnales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2015
In this paper we prove the Hyers-Ulam stability of the following K-quadratic functional equation ∑ k ∈ K f(x+ k.y)= Lf(x)+ Lf(y), x,y ∈ E, where E is a real (or complex) vector space.
Youssef Aribou   +3 more
doaj   +1 more source

K+ Block Is the Mechanism of Functional Asymmetry in Bacterial Na(v) Channels. [PDF]

open access: yesPLoS Computational Biology, 2016
Crystal structures of several bacterial Na(v) channels have been recently published and molecular dynamics simulations of ion permeation through these channels are consistent with many electrophysiological properties of eukaryotic channels.
Van Ngo   +4 more
doaj   +1 more source

A characterization of weighted peetre K-functionals

open access: yesJournal of Approximation Theory, 1989
Let \(X=L_ p[a,b]\) (1\(\leq p\leq \infty)\) and w a ``weight'' (a continuous and locally positive function in [a,b]). Let \(W^ k_ p(w)\) (k\(\in N)\) be the set of all functions which are locally absolutely continuous together with \(g'...g^{(k-1)}\) and \(\| w^ kg^{(k)}\|_ ...
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Functional factorial K-means analysis [PDF]

open access: yes, 2014
A new procedure for simultaneously finding the optimal cluster structure of multivariate functional objects and finding the subspace to represent the cluster structure is presented.
Yamamoto, Michio, Terada, Yoshikazu
core   +1 more source

Specialized functional diversity and interactions of the Na,K-ATPase

open access: yesFrontiers in Physiology, 2016
Na,K-ATPase is a protein ubiquitously expressed in the plasma membrane of all animal cells and vitally essential for their functions. A specialized functional diversity of the Na,K-ATPase isozymes is provided by molecular heterogeneity, distinct ...
Igor I. Krivoi, Vladimir V. Matchkov
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Generalized Jensen functional equation on restricted domain

open access: yesAnnals of the West University of Timisoara: Mathematics and Computer Science, 2014
We prove the Hyers-Ulam stability on restricted domains of generalized Jensen functional ...
Chahbi Abdellatif   +3 more
doaj   +1 more source

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