Results 61 to 70 of about 14,634,982 (301)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Association Between Functional Ankle Instability and Strength, Postural Stability, and Functional Performance in Adolescent Soccer Players [PDF]

open access: yesThe Asian Journal of Kinesiology
OBJECTIVES Functional ankle instability (FAI) is common in adolescent soccer players following recurrent ankle sprains and may influence physical function.
Han-Soo Park, Young-Nam Cha, Yu-Eun Lim
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Generalized Jensen functional equation on restricted domain

open access: yesAnnals of the West University of Timisoara: Mathematics and Computer Science, 2014
We prove the Hyers-Ulam stability on restricted domains of generalized Jensen functional ...
Chahbi Abdellatif   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A K-energy functional for complexified K\"ahler classes

open access: yes, 2023
The K-energy functional is extended to complexified K\"ahler classes, providing a variational approach to study the scalar curvature equation with B-field introduced by Schlitzer and Stoppa. The extended K-energy is convex along geodesics in the space of
Scarpa, Carlo
core  

K+ Block Is the Mechanism of Functional Asymmetry in Bacterial Na(v) Channels. [PDF]

open access: yesPLoS Computational Biology, 2016
Crystal structures of several bacterial Na(v) channels have been recently published and molecular dynamics simulations of ion permeation through these channels are consistent with many electrophysiological properties of eukaryotic channels.
Van Ngo   +4 more
doaj   +1 more source

A characterization of weighted peetre K-functionals

open access: yesJournal of Approximation Theory, 1989
Let \(X=L_ p[a,b]\) (1\(\leq p\leq \infty)\) and w a ``weight'' (a continuous and locally positive function in [a,b]). Let \(W^ k_ p(w)\) (k\(\in N)\) be the set of all functions which are locally absolutely continuous together with \(g'...g^{(k-1)}\) and \(\| w^ kg^{(k)}\|_ ...
openaire   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

open access: yes
Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi   +13 more
wiley   +1 more source

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