Results 71 to 80 of about 1,880,140 (284)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
On the general K-interpolation method for the sum and the intersection
Journal of Inequalities and Applications, 2016 Let ( A 0 , A 1 ) $(A_{0}, A_{1})$ be a compatible couple of normed spaces. We study the interrelation of the general K-interpolation spaces of the couple ( A 0 + A 1 , A 0 ∩ A 1 ) $(A_{0}+A_{1}, A_{0} \cap A_{1})$ with those of the couples ( A 0 , A 1 )
Irshaad Ahmed, Muhammad Awais
doaj +1 more source
A characterization of weighted peetre K-functionals
Journal of Approximation Theory, 1989 Let \(X=L_ p[a,b]\) (1\(\leq p\leq \infty)\) and w a ``weight'' (a continuous and locally positive function in [a,b]). Let \(W^ k_ p(w)\) (k\(\in N)\) be the set of all functions which are locally absolutely continuous together with \(g'...g^{(k-1)}\) and \(\| w^ kg^{(k)}\|_ ...
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Fluids and Barriers of the CNSBackground Glioblastoma (GBM) is the most prevalent and aggressive primary brain tumor in adults, characterized by rapid proliferation and invasive infiltration into normal brain tissue. Despite maximal resection and temozolomide (TMZ) chemotherapy, over
Jaewoo Shin +6 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Cuttlefish-Bone-Derived Hybrid Composite Scaffolds for Bone Tissue Engineering
NanomaterialsCurrent investigations into the fabrication of innovative biomaterials that stimulate cartilage development result from increasing interest due to emerging bone defects.
Vignesh Raj Sivaperumal +7 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Methods in Ecology and EvolutionHuman activities induce environmental changes, which can affect individuals' traits thereby leading to changes in functional diversity and finally in ecosystem functioning.
Laurie Anne Wojcik +3 more
doaj +1 more source
Generalized Jensen functional equation on restricted domain
Annals of the West University of Timisoara: Mathematics and Computer Science, 2014 We prove the Hyers-Ulam stability on restricted domains of generalized Jensen functional ...
Chahbi Abdellatif +3 more
doaj +1 more source