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Outbreak of Klebsiella pneumoniae carbapenemase–producing K pneumoniae: A systematic review

American Journal of Infection Control, 2016
First detected in the United States in 1996, Klebsiella pneumoniae carbapenemase (KPC) has spread internationally among gram-negative bacteria, especially K pneumoniae. These microorganisms can cause serious infections in hospitalized patients, and there are few therapeutic options, culminating in increased mortality. The objective of this study was to
James Albiero   +1 more
exaly   +3 more sources

First outbreak of Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae in Germany

European Journal of Clinical Microbiology & Infectious Diseases, 2010
We report the first outbreak of Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae in Germany. The presence of KPC was confirmed by polymerase chain reaction (PCR). The KPC-encoding plasmid was analysed by transconjugation experiments, DNA sequencing, Southern blotting and isoelectric focussing.
Wendt, Constanze   +9 more
openaire   +3 more sources

Ultrastructure and Viability of K. pneumoniae Treated with Fosfomycin

Zentralblatt für Bakteriologie. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie, 1980
The effect of Fosfomycin on K. pneumoniae ATCC 10031 was studied. The morphology on the electron microscopical level and the viability were markedly altered after application of 6 micrograms/ml and 60 micrograms/ml of Fosfomycin, respectively. These were chosen because they can be attained in man by oral or parenteral administration. Until 30 min after
openaire   +2 more sources

ГЕНЕТИЧЕСКАЯ ДЕТЕКЦИЯ ЛЕКАРСТВЕННОЙ УСТОЙЧИВОСТИ K. PNEUMONIAE

Всероссийская научно-практическая конференция «Экологический инжиниринг, агро- и биотехнологии», 2022
Инфекционные заболевания остаются одной из ведущих причин заболеваемости и смертности на нашей планете. Развитие резистентности у микробов - бактерий, вирусов, или паразитов для терапии не является ни удивительным, ни чем-то новым. Однако объем и масштаб этого явления является все возрастающим многонациональным кризисом общественного здравоохранения ...
openaire   +1 more source

MRP8/14 is a Protective Mediator in Murine Klebsiella (K.) Pneumoniae Induced Pneumonia

Annals of Paediatric Rheumatology, 2012
BACKGROUND: K. pneumoniae is a common cause of pneumonia-derived sepsis. MRP8 and MRP14 are the most abundant cytoplasmic proteins in neutrophils. They can form MRP8/14 heterodimers that are released during invasive infectious diseases. MRP8/14 reportedly exerts antimicrobial activity and enhances the pro-inflammatory response via Toll-like receptor ...
Ahmed Achouiti   +10 more
openaire   +1 more source

EXPLOSIVE OUTBREAK OF AN ATYPICAL PNEUMONIA ("K-8 FEVER")

Archives of Internal Medicine, 1952
SEVERE sporadic "viral" pneumonias have been cited as often giving rise to diagnostic and therapeutic problems. 1 During recent years previously unidentified diseases have been found to present themselves as pneumonia of an "atypical" nature. The advent of newer antibiotics to which some of these diseases readily respond has accentuated the importance ...
openaire   +2 more sources

Effect of a Metalloantibiotic Produced by Pseudomonas aeruginosa on Klebsiella pneumoniae Carbapenemase (KPC)-producing K. pneumoniae

Current Pharmaceutical Biotechnology, 2016
Multidrug-resistant organisms (MDRO) are a great problem in hospitals, where thousands of people are infected daily, with the occurrence of high mortality rates, especially in infections caused by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-producing Kpn).
Gilselena, Kerbauy   +14 more
openaire   +2 more sources

In vitro activity of minocycline combined with aminoglycosides against Klebsiella pneumoniae carbapenemase-producing K. pneumoniae

The Journal of Antibiotics, 2018
This study assessed the in vitro antibacterial activity of minocycline-aminoglycoside combination against Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae. Seventy non-duplicate clinical isolates of KPC-producing K. pneumoniae were collected from patients with bloodstream infections.
Ni, Wentao   +6 more
openaire   +2 more sources

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