Results 11 to 20 of about 11,042 (207)

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion [PDF]

Advanced Science
Ischemia‐reperfusion (I/R) injury in stroke causes severe neuronal damage through oxidative stress and metabolic dysfunction. Beyond its metabolic role, lactate can induce lysine lactylation, but its impact on neuroprotection remains unclear.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
doaj   +4 more sources

Structural basis of K11/K48-branched ubiquitin chain recognition by the human 26S proteasome [PDF]

Nature Communications
Beyond the canonical K48-linked homotypic polyubiquitination for proteasome-targeted proteolysis, K11/K48-branched ubiquitin (Ub) chains are involved in fast-tracking protein turnover during cell cycle progression and proteotoxic stress.
Piotr Draczkowski, Szu-Ni Chen, Ting Chen, Yong-Sheng Wang, Hsin-An Shih, Jessica Y. C. Huang, Ming-Chieh Tsai, Shu-Yu Lin, Steven Lin, Rosa Viner, Yuan-Chih Chang, Kuen-Phon Wu, Shang-Te Danny Hsu   +12 more
doaj   +3 more sources

The Design and Construction of K11: A Novel α-Helical Antimicrobial Peptide [PDF]

International Journal of Microbiology, 2012
Amphipathic α-helical antimicrobial peptides comprise a class of broad-spectrum agents that are used against pathogens. We designed a series of antimicrobial peptides, CP-P (KWKSFIKKLTSKFLHLAKKF) and its derivatives, and determined their minimum ...
Huang Jin-Jiang, Lu Jin-Chun, Lu Min, Huang Qing-Shan, Li Guo-Dong   +4 more
doaj   +5 more sources

Transformation and Summation Formulas for Exton's Functions K11, K14 And K15 [PDF]

مجلّة جامعة عدن للعلوم الأساسيّة والتّطبيقيّة, 2020
The aim of the present paper is to establish some transformation formulas for Exton's quadruple hypergeometric functions K11, K14 and K15. Several summation formulas for K11, K14 and K15 are also derived as an applications of our main results with the ...
Ahmed Ali Atash, Hussein Saleh Bellehaj
doaj   +3 more sources

RNF114 and RNF166 exemplify reader-writer E3 ligases that extend K11 polyubiquitin onto sites of MARUbylation [PDF]

EMBO Journal
Ubiquitin (Ub) cooperates with other post-translational modifications to provide a tiered opportunity for protein regulation. Deltex E3 ligases were previously implicated in ubiquitylation of ADP-ribose (ADPr)-containing macromolecules in vitro ...
Ivan Rodríguez Siordia, Kapil Upadhyaya, Jonathan N Pruneda   +2 more
exaly   +3 more sources

Synergistic effect and antibiofilm activity of the antimicrobial peptide K11 with conventional antibiotics against multidrug-resistant and extensively drug-resistant Klebsiella pneumoniae

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionInfections caused by drug-resistant Klebsiella pneumoniae are now a serious problem for public health, associated with high morbidity and mortality due to limited treatment options.
Warawan Eiamphungporn, Chawalit Chatupheeraphat, Jiratchaya Peamchai   +2 more
exaly   +3 more sources

The CCL-K11 ongoing key comparison. Final report for the year 2015

Metrologia, 2016
Lasers from two national metrological institutes (NMIs) were compared in 2015 as part of the CCL-K11 ongoing key comparison, initiated by the 13th meeting of the Comité Consultative des Longuers (CCL) in 2007. The absolute frequency of R(127) 11-5 transitions of molecular iodine was measured for these lasers following the technical ...
Seppä, Jeremias, Matus, Michael, Robertsson, Lennart, van den Berg, Steven, Czulek, Dariusz   +4 more
core   +6 more sources

Longitudinal Adaptive Functioning Outcomes in Children with Autism Spectrum Disorder During a 180 Day Open-Label Extension of K11-Tmax, a Consortium Probiotic Mix with Multivitamins [PDF]

Life
Autism spectrum disorder (ASD) is frequently associated with gastrointestinal symptoms, immune dysregulation, and altered microbiota-related signaling, supporting interest in microbiota-targeted interventions.
Deivis O. Guimaraes, Racire S. Silva, Lara A. Ferreira, Larissa Martinelli, Rebeca M. M. Werly, Raphaela F. Amorim, Lívia B. S. S. Holzbach, Roberto Badaró, Alex A. B. Santos, Elisardo C. Vasquez, Sarha A. L. de Queiroz   +10 more
doaj   +2 more sources

Identification of Bacteriophage K11 Genomic Promoters for K11 RNA Polymerase [PDF]

BMB Reports, 2002
Only one natural promoter that interacts with bacteriophage K11 RNA polymerase has so far been identified. To identify more, in the present study restriction fragments of the phage genome were individually assayed for transcription activity in vitro. The K11 genome was digested with two 4-bp-recognizing restriction enzymes, and the fragments cloned in ...
Eunsung Junn, Changwon Kang
exaly   +3 more sources

Kefir-derived probiotic mixture for children with autism spectrum disorder: a double-blind randomized clinical trial [PDF]

BMC Pediatrics
Purpose Emerging evidence suggests associations between gut microbiota patterns and autism-related behavioral and gastrointestinal features, increasing interest in probiotic interventions.
Sarha A. L. de Queiroz, Deivis O. Guimarães, Lara A. Ferreira, Larissa Martinelli, Rebeca M. M. Werly, Raphaela F. Amorim, Lívia B. S. S. Holzbach, Roberto Badaró, Alex A. B. Santos, Elisardo C. Vasquez, Racire S. Silva   +10 more
doaj   +2 more sources