Results 51 to 60 of about 11,042 (207)

Exocellular β-Lactamases of Streptomyces albus G and Strains R39 and K11 [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 1973
The β-lactamases excreted by the highly benzylpenicillin-susceptible Streptomyces strain R39 and the highly benzylpenicillin-resistant Streptomyces albus G were isolated and purified. Neither β-lactamase exhibited dd -carboxypeptidase activity. Both were anionic at
Johnson, Kenneth   +3 more
openaire   +3 more sources

METTL7A Downregulation Drives SLC1A5‐Mediated Glutamine Competition to Promote Tumor Proliferation and Suppress CD8+ T Cell Immunity in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
GC cells enhance glutamine accumulation by upregulating SLC1A5 expression. This upregulation not only boosts GC cell proliferation, but also outcompetes CD8+ T cells for glutamine and suppresses their antitumor immunity. Mechanistically, METTL7A deficiency in GC induces SLC1A5 overexpression via an m6A‐dependent pathway and N‐glycosylation ...
Mingjun Sun   +16 more
wiley   +1 more source

Comparison of Real Estate Management System in China and Poland

open access: yesReal Estate Management and Valuation, 2020
Real estate management systems differ all over the world. Differences arise from the different history of regions, different cultures and customs. The paper presents information about the real estate management systems in China and Poland, two extremely ...
Gross Marta, Lin Chao
doaj   +1 more source

Understanding K11‐ polyubiquitin recognition at the 26S Proteasome

open access: yesThe FASEB Journal, 2013
Ubiquitination, the covalent attachment of ubiquitin to target proteins, is a reversible post‐translational modification that regulates many important cellular processes. Ubiquitin chains linked at Lys48 (K48) serve as a signal for proteasomal degradation; whereas K63‐linked chains have non‐proteolytic function.
Joseph Chaney, Chittaranjan Das
openaire   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

open access: yesAdvanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He   +10 more
wiley   +1 more source

Compensation for Real Properties Acquired for Roads in Different Procedures - Comparative Analysis

open access: yesReal Estate Management and Valuation, 2017
Real properties acquired for the so-called public purpose, such as road investments, generate a one-off financial indemnity in the form of compensation paid to the expropriated owner.
Barańska Anna
doaj   +1 more source

Ways of Acquiring Land Property for the Construction of Province Roads

open access: yesReal Estate Management and Valuation, 2018
The topic of this article is related to issues connected with public roads. The thematic scope of the work includes the presentation and analysis of the legal regulations governing the acquisition of real estate under provincial public roads. The purpose
Noga Karol   +2 more
doaj   +1 more source

Tumor‐Intrinsic HEXB Drives Endothelial‐To‐Mesenchymal Transition and Confers Resistance to Anti‐Angiogenic Therapy in Glioblastoma

open access: yesAdvanced Science, EarlyView.
This study elucidates how glioblastoma tumors develop resistance to anti‐VEGF therapy through endothelial‐to‐mesenchymal transition (Endo‐MT). The researchers identify a novel signaling pathway where tumor‐derived HEXB stabilizes HSP60 to drive this vascular reprogramming.
Tianqi Liu   +13 more
wiley   +1 more source

The four known biplanes with k=11

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1979
The four known biplanes of order 9(k=11) are described in terms of their ovals, λ-chain structures, and automorphism groups. An exhaustive computer search for all biplanes of order 9 with certain chain structures has produced but two, one of which is new.
Chester J. Salwach, Joseph A. Mezzaroba
doaj   +1 more source

OTUD6A promotes prostate tumorigenesis via deubiquitinating Brg1 and AR

open access: yesCommunications Biology, 2022
OTUD6A, a deubiquitinase, is amplified in prostate cancer and correlates with poor survivability, increasing the growth of prostate cancer cell lines and PDX models.
Xuhong Fu   +11 more
doaj   +1 more source

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