Results 71 to 80 of about 55,507 (190)
Angewandte Chemie, EarlyView.Diese Studie beschreibt die Herstellung und Eigenschaften einer neuen Familie von o‐Terphenyl‐basierten Makrozyklen, TP[n] (n = 2‐8). Der Trimer bindet Phenylalanin in Wasser sehr effizient und ist dabei zehnmal selektiver als bei anderen Aminosäuren und aromatischen Neurotransmittern.
Swapnil Ghule +5 more
wiley +1 more source
Multiple E3 ligases control tankyrase stability and function
Nature Communications, 2023 Tankyrase 1 and 2 are ADP-ribosyltransferases that catalyze formation of polyADP-Ribose (PAR) onto themselves and their binding partners. Tankyrase protein levels are regulated by the PAR-binding E3 ligase RNF146, which promotes K48-linked ...
Jerome Perrard, Susan Smith
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.This study presents the synthesis and binding properties of a new family of o‐terphenyl‐based macrocycles, TP[n] (n = 2‐8). The trimer variant efficiently binds phenylalanine in water with a 10‐fold selectivity compared to other amino acids and aromatic neurotransmitters.
Swapnil Ghule +5 more
wiley +1 more source
Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers
Chemistry – A European Journal, EarlyView.ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda +5 more
wiley +1 more source
Surface hydration‐induced damage in tight oil‐bearing sandy conglomerate reservoirs
Deep Underground Science and Engineering, EarlyView.A series of techniques such as X‐ray diffraction, scanning electron microscopy, energy‐dispersive spectroscopy, conductivity tests, and infrared thermal imaging were used. The key findings are the identification of a two‐stage surface hydration process and the elucidation of the effects of various minerals and elements on the hydration process ...
Anbang Zhao +5 more
wiley +1 more source
Noisy weak-lensing convergence peak statistics near clusters of galaxies and beyond
, 2010 Taking into account noise from intrinsic ellipticities of source galaxies, in this paper, we study the peak statistics in weak-lensing convergence maps around clusters of galaxies and beyond.
Albrecht +22 more
core +1 more source
Monosaccharide‐Based Macrocyclic Receptors—History and Recent Applications
Helvetica Chimica Acta, EarlyView.This perspective provides an overview of most common applications of monosaccharide‐based macrocycles in molecular recognition over the past four decades. The most recent achievements, such as fluorescent ion sensing and selective amino acid binding in aqueous media, including the work from the author's lab, are highlighted. Potential future directions
Bartosz Lewandowski
wiley +1 more source
Examining Heuristics for Building - Work-in-Progress Valuations in Niger State Nigeria
Real Estate Management and Valuation, 2018 Where an investment decision on building work-in-progress (BWIP) is premised on the judgment of value, the technique of assessment must be accurate. The heuristic technique has not been able to achieve this goal.
Babatunde Isaiah Olajide
doaj +1 more source
Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12
Nature Communications, 2021 The tumor suppressor FBW7 is a substrate adaptor for the E3 ubiquitin ligase complex SKP1-CUL1-F-box (SCF) and itself a target for ubiquitylation. Here, the authors show that TRIP12 mediates branched K11-linked ubiquitylation of FBW7, to regulate its ...
Omar M. Khan +8 more
doaj +1 more source
Numerical modelling of rubber vibration isolators [PDF]
, 2003 An important cause for interior noise in vehicles is structure-borne sound from the engine. The vibrations of the source (engine) are transmitted to the receiver structure (the vehicle) causing interior noise in the vehicle. For this reason the engine is
Beijers, Clemens A.J., Boer, André de
core +1 more source