Results 41 to 50 of about 6,721 (196)

Leniency programs and socially beneficial cooperation: Effects of type I errors

Russian Journal of Economics, 2016
This study operationalizes the concept of hostility tradition in antitrust as mentioned by Oliver Williamson and Ronald Coase through erroneous law enforcement effects.
Natalia Pavlova, Andrey Shastitko
doaj   +1 more source

Selective modulation of NaV channel gating counteracts aberrant hyperexcitability and rescues motor function and survival in a model of spinal muscular atrophy

British Journal of Pharmacology, EarlyView.
Background and Purpose Spinal muscular atrophy (SMA) is a motor neuron disease caused by SMN1 gene loss, leading to reduced survival motor neuron (SMN) protein and progressive motor neuron degeneration. Although SMN‐restoring therapies improve outcomes, residual disease burden and non‐curative efficacy underscore the need for complementary treatments ...
Fernanda C. Cardoso, Jessica A. I. Muller, Yougang Zhang, Jean Giacomotto   +3 more
wiley   +1 more source

A Transitivity Analysis of the Clause in SiLozi Language (K21)

Scholars International Journal of Linguistics and Literature
The paper uses Systemic Functional Linguistics (henceforth SFL) to conduct a transitivity analysis of the clause in the siLozi language (K21) spoken in Zambia. The paper explores how the experience of the material and non-material world is construed through the grammar of the clause. The paper draws insights from Martin and Rose’s (2003) SFL to analyse
Humphrey M. Kapau, Pethias Siame, Benjamin Amoakohene, Kelvin Mambwe, Kennedy N. Kangwa   +4 more
openaire   +1 more source

Elementy analizy dynamicznej oceny skutków koncentracji na rynku właściwym [PDF]

internetowy Kwartalnik Antymonopolowy i Regulacyjny, 2015
Artykuł dotyczy kwestii związanych z dynamiczną oceną skutków (dla danego rynku właściwego) koncentracji przedsiębiorstw oraz, wywodzoną z tych skutków, dopuszczalnością koncentracji.
Wojciech J. Piwowarczyk
doaj  

Đánh giá khả năng trả nợ vay của khách hàng bằng các phương pháp phân loại

Tạp chí Khoa học Đại học Cần Thơ, 2017
Bài báo trình bày các phương pháp phân loại và những vấn đề tính toán trong áp dụng thực tế của chúng. Bài báo cũng đề nghị một thuật toán xác định xác suất tiên nghiệm trong phân loại bằng phương pháp Bayes tốt hơn các phương pháp khác.
Võ Văn Tài, Nghiêm Quang Thường, Nguyễn Thị Hồng Dân   +2 more
doaj   +1 more source

Family and Employer Perspectives on the Employment of Youth With Disabilities From a DisCrit Perspective

Child &Family Social Work, EarlyView.
ABSTRACT This study examines the experiences of families and employers in the employment processes of individuals with disabilities in Turkey, within the framework of the DisCrit (Disability Studies and Critical Race Theory) approach. The research was conducted through semi‐structured telephone interviews with 25 parents living in Turkey who have ...
A. Emel Sardohan Yildirim, Muhammed Ali Çankaya, Özlem Altindağ Kumaş   +2 more
wiley   +1 more source

Newly discovered clouting interplay between matrix metalloproteinases structures and novel quaternary Ammonium K21: computational and in-vivo testing

BMC Oral Health
Aims and objectives To analyze anti-MMP mode of action of Quaternary Ammonium Silane (QAS, codenamed as k21) by binding onto specific MMP site using computational molecular simulation and Anti-Sortase A (SrtA) mode of action by binding onto specific site
Ranjeet Ajit Bapat, Kit-Kay Mak, Mallikarjuna Rao Pichika, Jia Chern Pang, Seow Liang Lin, Suan Phaik Khoo, Umer Daood   +6 more
doaj   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

Integrated Passive Design Strategies for Enhancing Energy Performance of Hotel Buildings in Hot-Arid Climates: A Simulation-Based Study

HBRC Journal
Sustainable architectural design strategies offer effective solutions for enhancing energy efficiency and reducing operational costs in energy-intensive buildings, such as hotels in hot-arid climates.
Esraa Ebrahiem Abu-Elenain
doaj   +1 more source

Model‐Based Analysis with Mechanistic Insights to CAR‐T‐Cell Therapy Kinetics: Case Study with Axicabtagene Ciloleucel and Brexucabtagene Autoleucel

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1027-1040, October 2026.
Model‐informed drug development is increasingly used to support chimeric antigen receptor (CAR)‐T‐cell therapy programs. However, most population pharmacokinetic (PK) CAR‐T‐cell models available in literature are variations of an empirical piecewise‐linear model, which accurately describes the observed data but lacks a mechanistic foundation.
Anna M. Mc Laughlin, Martin Bergstrand, Ana Ruiz‐Garcia, Simone Filosto, Rhine Shen   +4 more
wiley   +1 more source