Results 61 to 70 of about 6,721 (196)

Precision Stereotactic Body Radiotherapy for Ultra‐Central NSCLC: Tailored Margins Reduce Toxicity Without Compromising Tumor Control

MedComm, Volume 7, Issue 8, August 2026.
A tailored non‐uniform PTV strategy (including PTVcrop and PTV_high/PTV_low) was used in SBRT for ultra‐central NSCLC to meet stringent OAR constraints. Notably, this SBRT strategy achieved favorable clinical outcomes, with an 84.6% 3‐year local control rate, a median PFS of 42.9 months. Additionally, treatment‐related toxicity was mild, with only 1.5%
Di Liu, Shuangyan Yang, Yun Chen, Ming Liu, Ruifeng Zhao, Minren Hu, Bin Su, QiongYa Wu, Hongyu Wu, Hui Liu, Jinming Yu, Yaping Xu   +11 more
wiley   +1 more source

Protein-Bound Uremic Toxin Profiling as a Tool to Optimize Hemodialysis. [PDF]

PLoS ONE, 2016
AIM:We studied various hemodialysis strategies for the removal of protein-bound solutes, which are associated with cardiovascular damage. METHODS:This study included 10 patients on standard (3 x 4 h/week) high-flux hemodialysis.
Sunny Eloot, Daniel Schneditz, Tom Cornelis, Wim Van Biesen, Griet Glorieux, Annemie Dhondt, Jeroen Kooman, Raymond Vanholder   +7 more
doaj   +1 more source

Machine Learning Enables Rapid Prediction of Acid‐Reducing Agent Drug Interactions: A Streamlined Complement to PBPK Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
Machine Learning Enables Rapid Prediction of Acid‐Reducing Agent Drug Interactions: A Streamlined Complement to PBPK Modeling. ABSTRACT pH‐dependent drug–drug interactions (DDIs) commonly occur when acid‐reducing agents (ARAs) are co‐administered with weakly basic drugs.
Yuanfang Qin, Lehua Yu, Tao Chen, Yonghui Zuo, Hongyun Wang, Guoping Yang, Qi Pei   +6 more
wiley   +1 more source

Enterococcus faecalis and Endodontic Treatment Failure: A Qualitative Systematic Review of Its Role and Elimination Strategies

Australian Endodontic Journal, Volume 52, Issue 2, Page 585-605, August 2026.
ABSTRACT The aim of this study was to synthesize evidence on the influence of Enterococcus faecalis on endodontic treatment failure and strategies for its elimination. This study followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines and was registered in PROSPERO (CRD420251022741).
Francine Santos Fernandes de Lima, Analia Gabriella Borges Ferraz Facury   +1 more
wiley   +1 more source

High‐Order Janus Bound States in the Continuum Assisted by Unidirectional Guided Resonances

Nanophotonics, Volume 15, Issue 14, 27 July 2026.
A high‐order Janus bound state in the continuum, featuring a q = −3 vortex in the upward radiation channel and a q = +1 vortex in the downward channel, is realized in truncated‐cone photonic crystal slabs by merging unidirectional guided resonances with a symmetry‐protected BIC, enabling direction‐dependent control of topological light emission ...
Zengping Su, Jue Li, Haoye Qin, Wenjing Lv, Yongkang Wang, Wei Li, Linhan Lin, Bo Li, Qinghua Song   +8 more
wiley   +1 more source

PK and PK/PD Modeling of Bcl2 Inhibitor S65487 in Patients With AML and Investigation of Nonlinearity With Microdosing

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 7, July 2026.
ABSTRACT This work aims to assess the S65487‐induced disruption of the B‐cell lymphoma‐2 (Bcl2)/Bcl2‐like protein 11 (Bim) complex at therapeutic doses via a pharmacokinetic/pharmacodynamic model and to reconcile pharmacokinetic data from microdoses and therapeutic doses in a single population pharmacokinetic model. The first model consists of a linear
Chloé Burlot, François Riglet, Mathilde Romagnoli, Ariane Leconte, Audrey Delmas, Antonin Schmitt, Sylvain Fouliard   +6 more
wiley   +1 more source

Magnetic Resonance Imaging Evaluation of Functional Differences Between In Vivo Human Kidneys and Discarded Human Kidneys During Ex Vivo Normothermic Machine Perfusion

Artificial Organs, Volume 50, Issue 7, Page 1037-1051, July 2026.
Comparative MRI of in vivo kidneys and ex vivo donor kidneys during NMP revealed marked physiological differences and limited correspondence with conventional perfusion or injury metrics. These distinct ex vivo MRI signatures emphasize the need to consider parameters beyond conventional in vivo functional markers when assessing organ viability during ...
Tim L. Hamelink, Chris L. Jaynes, L. Annick van Furth, Johannes Castelein, Nathan Ooms, Veerle A. Lantinga, Baran Ogurlu, Xiaopeng Zhou, Ulrike Dydak, Henri G. D. Leuvenink, Anna Krarup Keller, Ronald J. H. Borra, Cyril Moers   +12 more
wiley   +1 more source

La tutela della concorrenza nell’ordinamento italiano: dal codice civile del 1942 alla riforma costituzionale del 2001 (The protection of competition in the Italian legal system: from the civil code of 1942 to the constitutional reform of 2001)

Moneta e Credito, 2015
L'articolo ricorda il processo di sviluppo della legislazione antitrust in Italia, dal codice civile del 1942 alle riforme costituzionali del 2011. Il testo del discorso tenuto al convegno "Mercato e Concorrenza", il 18 novembre 2015,  organizzato dall ...
Mario Libertini
doaj   +1 more source

Combating Information Disorder in Healthcare: A Vaccine Supply Chain Case

Journal of Business Logistics, Volume 47, Issue 3, July 2026.
ABSTRACT The COVID‐19 vaccine supply chain faced unprecedented disruption from information disorder (collectively, misinformation, disinformation, and malinformation (MDM)). While prior research has examined the societal and health consequences of information disorder, little is known about how it disrupts supply chain management (SCM) or how supply ...
Derek Dubois, Muhammad Hasan Ashraf, Mehmet G. Yalcin, Rabia Hos   +3 more
wiley   +1 more source

Molecular cloning and expression analysis of ChCAO gene in leaf art formation of Cymbidium hybrid

Xibei zhiwu xuebao
[ Objective ] Chlorophyllide a oxygenase ( CAO ) is a key enzyme in the formation of chlorophyll b. Cloning and expression analysis of CAO genes may be helpful in exploring their function in regulating leaf color ...
LIN Rongyan, KONG Lan , WU Jianshe , LIN Bing , ZHONG Huaiqin   +4 more
doaj   +1 more source