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Tilorone: a Broad-Spectrum Antiviral Invented in the USA and Commercialized in Russia and beyond. [PDF]

Pharm Res, 2020
Ekins S, Lane TR, Madrid PB.
europepmc   +1 more source

Rarely listed essential medicines in 158 national lists. [PDF]

J Pharm Policy Pract
Ul Haq MZ, Heredia C, Rizvi A, Workentin A, Persaud N.   +4 more
europepmc   +1 more source

Antiviral strategies against influenza virus: an update on approved and innovative therapeutic approaches. [PDF]

Cell Mol Life Sci
Bonomini A, Mercorelli B, Loregian A.
europepmc   +1 more source

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Evaluation of Kagocel Genotoxicity

Bulletin of Experimental Biology and Medicine, 2019
Antiviral drug Kagocel in concentrations of 0.0008, 0.004, 0.02, 0.1, 0.5, and 2.5 mg/ml with or without metabolic activation does not induce gene mutations in S. typhimurium strains ТА98, ТА100, ТА1535, and ТА1537 and in a combination of E. coli strains pKM101 and uvrA.
Anna Vychuzhanina, Aliy Zhanataev, Andrey D. Durnev   +2 more
exaly   +3 more sources

Experimental Assessment of the Effect of Kagocel on Reproductive Function in Pubertal Male Rats

Bulletin of Experimental Biology and Medicine, 2017
We studied possible toxic effects of antiviral drug Kagocel on reproductive function in pubertal male rats. The drug was administered in therapeutic and 10-fold higher doses throughout the spermatogenesis cycle (48 days). Kagocel did not reduce mating and fertilizing capacities, did not suppress spermatogenesis, and had no toxic effects on the ...
Anna Vychuzhanina, Tatiana Borovskaya, Marina Poluektova   +2 more
exaly   +3 more sources

Study of Pharmacokietics of tritium-labeled Kagocel

Farmatsiya-Moscow, 2019
A.A. Andreev-Andrievsky, A.S. Popova, E.A. Lagereva, M.A. Mashkin, B.A. Rudoy, Yu.G. Kazaishvili, V.S. Shchervbakova   +6 more
exaly   +2 more sources

Effects of Kagocel® on the Counts of Multipotent Stromal Cells, Expression of Cytokine Genes in Primary Cultures of Bone Marrow Stromal Cells, and Serum Cytokine Concentrations in CBA Mice

Bulletin of Experimental Biology and Medicine, 2015
The efficiency of cloning of bone marrow multipotent stromal cells (ECF-MSC) from CBA mice and the MSC counts in the femoral bone increased 24 h after a single in vivo (but not in vitro) injection of kagocel (active substance of antiviral drug Kagocel (®) ) 1.4 times (in response to 50-80 μg) and 4.6 times (in response to 250 μg).
Maria V Konopleva, V G Nesterenko, Yu F Gorskaya   +2 more
exaly   +3 more sources

EVALUATION OF THE EFFICACY, TOLERABILITY AND SAFETY OF THE ANTIVIRAL DRUG «KAGOCEL»

Vestnik of the Kyrgyz-Russian Slavic University
Acute respiratory viral infection is a general term for clinically and morphologically similar acute inflammatory diseases of the respiratory tract and lungs caused by viruses tropic to the ciliated epithelium of the respiratory tract. It is the most common group of diseases in the world, combining influenza, respiratory syncytial, rhinovirus ...
M A Madaminova
exaly   +2 more sources

SYNTHESIS OF TRITIUM-LABELLED POLYMERIC KAGOCEL SUBSTANCE: TRITIUM THERMAL ACTIVATION METHOD

Farmatsiya-Moscow, 2018
G.A. Badun, M.G. Chernysheva, Yu.G. Kazaishvili, B.A. Rudoy   +3 more
exaly   +2 more sources