Results 111 to 120 of about 48,573 (291)
Development of Spontaneous Recurrent Seizures after Kainate-Induced Status Epilepticus
Journal of Neuroscience, 2009 Acquired epilepsy (i.e., after an insult to the brain) is often considered to be a progressive disorder, and the nature of this hypothetical progression remains controversial.
Philip A. Williams +6 more
semanticscholar +1 more source
LTD expression is independent of glutamate receptor subtype
Frontiers in Synaptic Neuroscience, 2014 Long-term depression (LTD) is a form of synaptic plasticity that plays a major role in the activity-dependent reshaping of synaptic transmission.
Adam J Granger, Roger A Nicoll
doaj +1 more source
AMPA receptors and seizures mediate hippocampal radial glia-like stem cell proliferation. [PDF]
, 2018 Neurogenesis is sustained throughout life in the mammalian brain, supporting hippocampus-dependent learning and memory. Its permanent alteration by status epilepticus (SE) is associated with learning and cognitive impairments.
Gray, WP +6 more
core +3 more sources
Oral Supplementation With a Bovine Thymus Extract Reduces Neuronal Excitability in Aging Mice
FASEB BioAdvances, Volume 8, Issue 2, February 2026.Oral supplementation of aging mice with a nuclear fraction extract of bovine thymus (TNF) leads to significant increases in GAD65, GAD67, and β2/β3 subunits of the GABAA receptor, more so with high dose (HD) TNF treatment compared to low dose (LD) and control condition.
Abdeslem El‐Idrissi +2 more
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 1998 In the present study, we report that low concentrations of the glutamate ionotropic agonist kainate decreased the turnover of [3H]-phosphoinositides ([3H]-InsPs) induced by muscarinic receptors in the chick embryonic retina.
G. Sanches, A.L.M. Ventura
doaj +1 more source
Clinical and Translational Science, Volume 19, Issue 2, February 2026.ABSTRACT Immune checkpoint regulators can improve neurological functions in Alzheimer's disease. However, it remains blurred whether these regulators may ameliorate temporal lobe epilepsy (TLE) and TLE‐related cognitive impairment. This study analyzed the bulk transcriptomic data of human TLE hippocampi by bioinformatics.
Man Li +3 more
wiley +1 more source
Plasticity of GABA(B) receptor-mediated heterosynaptic interactions at mossy fibers after status epilepticus [PDF]
, 2003 Several neurotransmitters, including GABA acting at presynaptic GABAB receptors, modulate glutamate release at synapses between hippocampal mossy fibers and CA3 pyramidal neurons.
Bowery, N.G. +5 more
core
Anterior Olfactory Nucleus [PDF]
, 2008 This report contains a gene expression summary of the anterior olfactory nucleus (AON), derived from the Allen Brain Atlas (ABA) in situ hybridization mouse data set.
Allen Institute for Brain Science +3 more
core +2 more sources
Obesity, Volume 34, Issue 1, Page 175-187, January 2026.ABSTRACT Objective Topiramate is a medication used off‐label, or in combination with phentermine, for the management of obesity. However, its mechanism of action remains elusive. As many obesity medications target the brain, we aimed to determine if topiramate influences the activity of hypothalamic melanocortin neurons known to regulate energy balance.
Moein Minbashi Moeini +4 more
wiley +1 more source
BMC Medical Imaging, 2011 Background Increased functionality of efflux transporters at the blood-brain barrier may contribute to decreased drug concentrations at the target site in CNS diseases like epilepsy.
Lammertsma Adriaan A +7 more
doaj +1 more source