Results 101 to 110 of about 47,334 (259)
Neuroinflammatory targets and treatments for epilepsy validated in experimental models [PDF]
, 2017 A large body of evidence that has accumulated over the past decade strongly supports the role of inflammation in the pathophysiology of human epilepsy.
Aronica, Eleonora +17 more
core +5 more sources
Epilepsia, Volume 67, Issue 4, Page 1614-1626, April 2026.Abstract Objective One‐third of patients with epilepsy, particularly those with mesial temporal lobe epilepsy (MTLE), remain resistant to medication. Resective surgery, the gold standard, is highly invasive and carries significant risks. Here, using a mouse model, we explored the potential of microbeam radiation therapy (MRT), a new technique based on ...
Loan Samalens +8 more
wiley +1 more source
LTD expression is independent of glutamate receptor subtype
Frontiers in Synaptic Neuroscience, 2014 Long-term depression (LTD) is a form of synaptic plasticity that plays a major role in the activity-dependent reshaping of synaptic transmission.
Adam J Granger, Roger A Nicoll
doaj +1 more source
Glia, Volume 74, Issue 4, April 2026.Ronzano et al. show that neuronal activity promotes node‐like cluster (NLC) formation before (re)myelination by regulating β1Nav and Nav1.1, which are essential for NLC assembly. This may represent an intermediate step in activity‐driven myelination and contribute to the regulation of axonal conduction.
Rémi Ronzano +10 more
wiley +1 more source
Fathoming the kynurenine pathway in migraine: why understanding the enzymatic cascades is still critically important [PDF]
, 2015 Kynurenine pathway, the quantitatively main branch of tryptophan metabolism, has been long been considered a source of nicotinamide adenine dinucleotide, although several of its products, the so-called kynurenines, are endowed with the capacity to ...
CURTO, MARTINA +4 more
core +1 more source
Journal of Neuroscience, 2012 Kainate receptors can be subject to voltage-dependent block by intracellular polyamines, which causes inward rectification of the current–voltage relationship.
J. Fisher, D. Mott
semanticscholar +1 more source
Kainate receptors: on the dark side [PDF]
The Journal of Physiology, 2014 Synaptic glutamate receptors can be divided into metabotropic receptors, an eight-member GPCR family, and ionotropic glutamate receptors, a three-member family of NMDA, kainate, and AMPA tetrameric receptors. The most neglected are the five subunit (GluK1–5) kainate receptors, often either lumped with the AMPA receptors because of pharmacological ...
openaire +2 more sources
Plasticity of GABA(B) receptor-mediated heterosynaptic interactions at mossy fibers after status epilepticus [PDF]
, 2003 Several neurotransmitters, including GABA acting at presynaptic GABAB receptors, modulate glutamate release at synapses between hippocampal mossy fibers and CA3 pyramidal neurons.
Bowery, N.G. +5 more
core
European Journal of Neuroscience, Volume 63, Issue 8, April 2026.Numerical cognition arises from conserved mechanisms linking genes, neural circuits and behaviour. Using zebrafish as a tractable model, behavioural assays, whole‐brain imaging and genetic analyses can be integrated to identify neural and molecular bases of quantity discrimination. This framework provides a platform for studying numerical cognition and
Mirko Zanon +3 more
wiley +1 more source
Augmentation of Ca2+ signaling in astrocytic endfeet in the latent phase of temporal lobe epilepsy
Frontiers in Cellular Neuroscience, 2015 Astrocytic endfeet are specialized cell compartments whose important homeostatic roles depend on their enrichment of water and ion channels anchored by the dystrophin associated protein complex.
Karolina eSzokol +19 more
doaj +1 more source