Results 101 to 110 of about 24,046 (180)

AMPA receptors are the major mediators of excitotoxic death in mature oligodendrocytes

Neurobiology of Disease, 2003
Myelination of axons is important for central nervous system function, but oligodendrocytes, which constitute CNS myelin, are vulnerable to excitotoxic injury and death.
Elizabeth A Leuchtmann, Andrea E Ratner, Rattanavijit Vijitruth, Yun Qu, John W McDonald   +4 more
doaj   +1 more source

Kainate receptors are involved in synaptic plasticity.

, 1999
International audienceThe ability of synapses to modify their synaptic strength in response to activity is a fundamental property of the nervous system and may be an essential component of learning and memory.
Collingridge, G. L., Ken H. Ho, Michael C. Parry, Ann Ogden, Parry, M. C., Zuner A. Bortolotto, Michel Vignes, Mary Gates, Bleakman, D., Clarke, V. R., Lodge, D., David Lodge, Vernon R. J. Clarke, Robert Fantaske, Vignes, M., Paul L. Ornstein, Caroline M. Delany, Ilse Smolders, Graham L. Collingridge, David Bleakman, Ho, K. H., Bortolotto, Z. A., Ogden, A., Fantaske, R., Ornstein, P. L., Delany, C. M., Miu, P., Bradford T. Brinton, Brinton, B. T., Smolders, I., Peter Miu, Gates, M.   +31 more
core   +1 more source

Kainate Receptors Presynaptically Downregulate GABAergic Inhibition in the Rat Hippocampus [PDF]

, 1997
9 páginas, 5 figuras.Using microcultured neurons and hippocampal slices, we found that under conditions that completely block AMPA receptors, kainate induces a reduction in the effectiveness of GABAergic synaptic inhibition.
Rodríguez-Moreno, Antonio, Lerma Gómez, Juan, Lerma, Juan, Herreras, Óscar   +3 more
core   +1 more source

The Anticonvulsant and Antioxidant Effects of Berberine in Kainate-induced Temporal Lobe Epilepsy in Rats

Basic and Clinical Neuroscience, 2014
Introduction: Temporal lobe epilepsy(TLE) is a long lasting neurological disorder in which patients suffer from spontaneous seizures. New treatments with novel mechanisms of action are needed to help those patients whose seizures are resistant to ...
Tourandokht Baluchnejadmojarad, Mehrdad Roghani   +1 more
doaj  

The effects of antidepressant drugs on kainate receptor mRNA levels

, 1991
We have measured the levels of kainate receptor mRNA in rat brains following the injection of antidepressant drugs over a time course up to 32 days. Over this period imipramine and fluvoxamine elicited a rise in kainate receptor mRNA levels to a maximum ...
Buckland, Paul Robert, O'Donovan, Michael Conlon, McGuffin, Peter, Havard, H. L.   +3 more
core   +1 more source

Kainate receptors in hippocampal CA3 subregion: evidence for a role in regulating neurotransmitter release

, 1998
The hippocampal CA3 subregion of the rat is characteristically enriched in kainate receptors. At the synaptic level, the subcellular localization of these receptors is still a matter of debate.
Carvalho, Arsélio P., Malva, João O., Carvalho, Caetana M.   +2 more
core   +1 more source

Kainate receptors: Perspectives from the past decade

, 2001
10 páginas, 5 figuras.-- Edited by: L. Turski, D.D. Schoepp and E.A. Cavalheiro.The potent excitatory amino acid glutamate mediates its excitatory effects through a wide variety of specific ionotropic receptors, including NMDA, AMPA and kainate receptors.
Rodríguez-Moreno, Antonio, Paternain, Ana V., Lerma Gómez, Juan, Guinea Díaz, Domingo   +3 more
core  

Possible Role of Akt in Mossy Fiber Sprouting: Akt Activity and CA3 Mossy Fiber Sprouting in a Kainate Model of Epilepsy

Journal of Tropical Life Science
The most prevalent pathological phenomenon observed in patients with epilepsy is hippocampal mossy fiber sprouting (MFS), which is thought to be associated with epileptic progression, such as worsening seizure control, cognitive function, and behavior ...
Machlusil husna, Kusworini Handono, Hidayat Sujuti, Aulanni'am Aulanni'am   +3 more
doaj   +1 more source

Sigma-1 Expression in Chronic Mouse Models of Temporal Lobe Epilepsy. [PDF]

Mol Neurobiol
Stocker VM, Lad C, Markov A, Potschka H, von Rüden EL.   +4 more
europepmc   +1 more source

Corrigendum: Histological Correlates of Diffusion-Weighted Magnetic Resonance Microscopy in a Mouse Model of Mesial Temporal Lobe Epilepsy

Frontiers in Neuroscience, 2020
Katharina Göbel-Guéniot, Katharina Göbel-Guéniot, Johannes Gerlach, Johannes Gerlach, Robert Kamberger, Jochen Leupold, Jochen Leupold, Dominik von Elverfeldt, Dominik von Elverfeldt, Jürgen Hennig, Jürgen Hennig, Jürgen Hennig, Jürgen Hennig, Jan G. Korvink, Carola A. Haas, Carola A. Haas, Carola A. Haas, Carola A. Haas, Pierre LeVan, Pierre LeVan, Pierre LeVan, Pierre LeVan, Pierre LeVan   +22 more
doaj   +1 more source