Results 111 to 120 of about 22,259 (219)

Kainate receptors in hippocampal CA3 subregion: evidence for a role in regulating neurotransmitter release

open access: yes, 1998
The hippocampal CA3 subregion of the rat is characteristically enriched in kainate receptors. At the synaptic level, the subcellular localization of these receptors is still a matter of debate.
Carvalho, Arsélio P.   +2 more
core   +1 more source

Kainate Receptors Presynaptically Downregulate GABAergic Inhibition in the Rat Hippocampus

open access: yes, 1997
9 páginas, 5 figuras.Using microcultured neurons and hippocampal slices, we found that under conditions that completely block AMPA receptors, kainate induces a reduction in the effectiveness of GABAergic synaptic inhibition.
Rodríguez-Moreno, Antonio   +3 more
core   +1 more source

PTEN inhibition protects CA3 neurons from kainate-induced excitotoxicity.

open access: yes, 2014
Nissl-staining of hippocampus sections of mice treated with saline (A, control), with kainate (B, KA) or with both kainate and bpv(pic) (C, KA+I), killed one day after treatment (scale bar: 1 mm). A1. CA3 area of control animals (ctr) treated with saline
Valentina Grande (647515)   +2 more
core   +1 more source

Antagonism of recombinant and native GluK3-containing kainate receptors

open access: yes, 2009
A number of kainate receptor antagonists have shown selectivity for receptors containing the GluK1 subunit. Here, we analyze the effects of these GluK1 antagonists on currents mediated by recombinant homomeric GluK3 and heteromeric GluK2/3 receptors ...
Pinheiro, PS   +3 more
core   +2 more sources

Kainate receptors: an interplay between excitatory and inhibitory synapses

open access: yes, 1998
5 páginas, 3 figuras.The potent excitatory amino acid glutamate mediates its excitatory effects through a great variety of specific ionotropic receptors, including NMDA, AMPA and kainate receptors.
Lerma Gómez, Juan   +2 more
core   +1 more source

Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice

open access: yes, 1998
L-glutamate, the neurotransmitter of the majority of excitatory synapses in the brain, acts on three classes of ionotropic receptors: NMDA (N-methyl-D-aspartate), AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) and kainate receptors ...
Heinemann, S. F.   +21 more
core   +1 more source

Kainate receptors: Perspectives from the past decade

open access: yes, 2001
10 páginas, 5 figuras.-- Edited by: L. Turski, D.D. Schoepp and E.A. Cavalheiro.The potent excitatory amino acid glutamate mediates its excitatory effects through a wide variety of specific ionotropic receptors, including NMDA, AMPA and kainate receptors.
Rodríguez-Moreno, Antonio   +3 more
core  

Two types of kainate response in cultured rat hippocampal neurons

open access: yes, 1991
1. Two different types of kainate response were recorded in cultured rat hippocampal neurons with the use of the whole-cell and outside-out configurations of the patch-clamp technique. 2.
M. Iino, S. Ozawa, K. Tsuzuki
core   +1 more source

Possible Role of Akt in Mossy Fiber Sprouting: Akt Activity and CA3 Mossy Fiber Sprouting in a Kainate Model of Epilepsy

open access: yesJournal of Tropical Life Science
The most prevalent pathological phenomenon observed in patients with epilepsy is hippocampal mossy fiber sprouting (MFS), which is thought to be associated with epileptic progression, such as worsening seizure control, cognitive function, and behavior ...
Machlusil husna   +3 more
doaj   +1 more source

Mast Cells In Kainate Receptor Knockout Mice

open access: yes, 2015
Kainate receptor knockout mice have unique differences within their immune system. They exhibit an attenuated TH2 branch, while maintaining a robust TH1 response.
Elkovich, Andrea J
core   +1 more source

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