Results 111 to 120 of about 47,334 (259)

Anterior Olfactory Nucleus [PDF]

open access: yes, 2008
This report contains a gene expression summary of the anterior olfactory nucleus (AON), derived from the Allen Brain Atlas (ABA) in situ hybridization mouse data set.
Allen Institute for Brain Science   +3 more
core   +2 more sources

Pharmacological manipulation of the immediate effects of spinal trauma in neonatal rats reveals a crucial role for TRPV4 receptors

open access: yesThe Journal of Physiology, Volume 604, Issue 7, Page 3077-3093, 1 April 2026.
Abstract figure legend A, schematic illustration of the ventral aspect of an ex vivo preparation of the entire CNS from a neonatal rat subjected to a calibrated thoracic impact. The trauma induced a large depolarising injury potential (DIP, black trace) recorded from the L5 ventral root (VRrL5), which was markedly reduced by transient receptor ...
Atiyeh Mohammadshirazi   +5 more
wiley   +1 more source

Neonatal hypoxic preconditioning involves vascular endothelial growth factor

open access: yesNeurobiology of Disease, 2007
We studied hypoxic preconditioning (HxP) in the murine developing brain, focusing on the role for vascular endothelial growth factor (VEGF). Newborn mice were used as follows: (1) HxP (or normoxia) then intracerebral (i.c.) NMDA or AMPA-kainate agonist; (
Vincent Laudenbach   +8 more
doaj   +1 more source

Abnormal hippocampal melatoninergic system: a potential link between absence epilepsy and depression-like behavior in WAG/Rij rats? [PDF]

open access: yes, 2018
Absence epilepsy and depression are comorbid disorders, but the molecular link between the two disorders is unknown. Here, we examined the role of the melatoninergic system in the pathophysiology of spike and wave discharges (SWDs) and depression-like ...
Battaglia, Giuseppe   +8 more
core   +1 more source

(R)-[11C]Verapamil PET studies to assess changes in P-glycoprotein expression and functionality in rat blood-brain barrier after exposure to kainate-induced status epilepticus

open access: yesBMC Medical Imaging, 2011
Background Increased functionality of efflux transporters at the blood-brain barrier may contribute to decreased drug concentrations at the target site in CNS diseases like epilepsy.
Lammertsma Adriaan A   +7 more
doaj   +1 more source

Connexin36 knockout mice display increased sensitivity to pentylenetetrazol-induced seizure-like behaviors [PDF]

open access: yes, 2010
Large-scale synchronous firing of neurons during seizures is modulated by electrotonic coupling between neurons via gap junctions. To explore roles for connexin36 (Cx36) gap junctions in seizures, we examined the seizure threshold of connexin36 knockout (
Cursons, Raymond T.   +7 more
core   +2 more sources

Increased expression of matrix metalloproteinase-9 in patients with temporal lobe epilepsy [PDF]

open access: yes, 2014
Aim: The molecular mechanism of epileptogenesis in temporal lobe epilepsy is still unclear. Experimental studies have suggested that matrix metalloproteinases have important roles in this process, but human studies are limited.
Acar, Feridun   +3 more
core   +1 more source

Motor Neurons Are Selectively Vulnerable to AMPA/Kainate Receptor-Mediated Injury In Vitro

open access: yesJournal of Neuroscience, 1996
The nonphosphorylated neurofilament marker SMI-32 stains motor neurons in spinal cord slices and stains a subset of cultured spinal neurons [“large SMI-32(+) neurons”], which have a morphology consistent with motor neurons identified in vitro: large cell
S. Carriedo, H. Yin, J. Weiss
semanticscholar   +1 more source

Serotonin Modulates Oscillations of the Membrane Potential in Isolated Spinal Neurons from Lampreys [PDF]

open access: yes, 2002
Studies were performed on spinal neurons from lampreys isolated by an enzymatic/mechanical method using pronase. The effects of 100 µM serotonin (5-HT) on membrane potential oscillations induced by a variety of excitatory amino acids were studied.
Batueva, I. V.   +4 more
core   +1 more source

Unique functions of kainate receptors in the brain are determined by the auxiliary subunit Neto1

open access: yesNature Neuroscience, 2011
Ionotropic glutamate receptors principally mediate fast excitatory transmission in the brain. Among the three classes of ionotropic glutamate receptors, kainate receptors (KARs) display a categorical brain distribution, which has been historically ...
Christoph Straub   +6 more
semanticscholar   +1 more source

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