Results 121 to 130 of about 22,259 (219)
Functional validation of Heteromeric Kainate receptor models
Kainate receptors require the presence of external ions for gating. Most work thus far has been performed on homomeric GluK2 but, in vivo, kainate receptors are likely heterotetramers. Agonists bind to the ligand-binding domain (LBD) which is arranged as
Musgaard, Maria +10 more
core +1 more source
Modulation of Kainate-Induced Excitotoxicity in Rats [PDF]
Kainic acid has been used widely as an effective model of excitotoxic neurodegeneration. Using both the intraperitoneal and intrahippocampal routes of injection, we have shown that kainate selectively damages discrete populations of cells in the ...
Jones, Paul A
core
Nuclear factor kappa B-mediated kainate neurotoxicity in the rat and hamster hippocampus.
Administration of the excitotoxin kainate produces seizure activity and selective neuronal death in various brain areas. We examined the degeneration pattern of hippocampal neurons following systemic injections of kainate in the hamster and the rat.
Choi, I +9 more
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Mapping the multi-domain allosteric network for CKAMP44 modulation of AMPA receptors. [PDF]
Bharti P, Visal S, Vinnakota R, Kumar J.
europepmc +1 more source
Kainate Receptors in Sensory Neurons: Molecular Identity and Functional Relevance to Pain. [PDF]
Degiorgi S, Lerma J.
europepmc +1 more source
Functional kainate-selective glutamate receptors in cultured hippocampal neurons
5 páginas, 5 figuras.Glutamate mediates fast synaptic transmission at the majority of excitatory synapses throughout the central nervous system by interacting with different types of receptor channels. Cloning of glutamate receptors has provided evidence
Paternain, Ana V. +3 more
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Acute Seizure Susceptibility and Chronic Vascular Malformation in a Developmental Mouse Model of Sturge-Weber Syndrome. [PDF]
Truver N, Solomon C, Comi A.
europepmc +1 more source
A comparative study of NETO1 and NETO2 on channel-opening kinetics of GluK2 kainate receptors. [PDF]
Saunders N, Niu L.
europepmc +1 more source

