Results 131 to 140 of about 48,573 (291)
Comparative Antagonism of Kainate‐activated Kainate and AMPA Receptors in Hippocampal Neurons
AbstractNative kainate receptors expressed by cultured hippocampal cells were studied in the whole‐cell configuration of the patch‐clamp technique by using a fast perfusion system. About 80% of the neurons expressed kainate receptors independently of the time in culture (0–4 days), which coincided with the number of cells immunoreactive for a ...
Paternain, Ana V. +3 more
openaire +3 more sources
Motor Neurons Are Selectively Vulnerable to AMPA/Kainate Receptor-Mediated Injury In Vitro
The nonphosphorylated neurofilament marker SMI-32 stains motor neurons in spinal cord slices and stains a subset of cultured spinal neurons [“large SMI-32(+) neurons”], which have a morphology consistent with motor neurons identified in vitro: large cell
S. Carriedo, H. Yin, J. Weiss
semanticscholar +1 more source
AMPA receptors are the major mediators of excitotoxic death in mature oligodendrocytes
Myelination of axons is important for central nervous system function, but oligodendrocytes, which constitute CNS myelin, are vulnerable to excitotoxic injury and death.
Elizabeth A Leuchtmann +4 more
doaj +1 more source
Introduction: Temporal lobe epilepsy(TLE) is a long lasting neurological disorder in which patients suffer from spontaneous seizures. New treatments with novel mechanisms of action are needed to help those patients whose seizures are resistant to ...
Tourandokht Baluchnejadmojarad +1 more
doaj
The Lurcher Mutation Identifies δ2 as an AMPA/Kainate Receptor-Like Channel That Is Potentiated by Ca2+ [PDF]
Lonnie P. Wollmuth +5 more
openalex +1 more source
Isolation and social instigation in animal models of aggression: effects of an mGLU1 receptor antagonist administration [PDF]
Isolate-induced aggression in male mice is a model widely used in psychoparmacology of aggression. Animals are usually isolated for 30 days and subsequently treated and confronted with an anosmic opponent in a neutral area.
Martin-Lopez, Maria Mercedes
core
Astronomi, kozmoloji ve kozmogoni konusunda İslam dünyasında yapılan çalışmaları çok kısa olarak zikrederek konumuza girelim: XVII. yüzyıl başlarına dek astronomiye ilişkin çalışmalar çıplak gözle gözleme dayanıyordu. Astronomideki gelişmeler teleskobun bulunmasıyla deneysel nitelik kazanmış ve hızla gelişmiştir.
openaire +3 more sources
Distinct subunits in heteromeric kainate receptors mediate ionotropic and metabotropic function at hippocampal mossy fiber synapses [PDF]
Heteromeric kainate receptors (KARs) containing both glutamate receptor 6 (GluR6) and KA2 subunits are involved in KAR-mediated EPSCs at mossy fiber synapses in CA3 pyramidal cells.
Coussen, F +4 more
core
The most prevalent pathological phenomenon observed in patients with epilepsy is hippocampal mossy fiber sprouting (MFS), which is thought to be associated with epileptic progression, such as worsening seizure control, cognitive function, and behavior ...
Machlusil husna +3 more
doaj +1 more source
The Effects of Serotonin on Functionally Diverse Isolated Lamprey Spinal Cord Neurons [PDF]
The experiments reported here showed that application of serotonin (5-hydroxytryptamine, 5-HT) (100 µ M) did not induce any significant current through the membranes of any of the spinal neurons studied (n = 62).
Batueva, I. V. +4 more
core +1 more source

