Results 21 to 30 of about 48,573 (291)
The Perils of Navigating Activity-Dependent Alternative Splicing of Neurexins
Frontiers in Molecular Neuroscience, 2021 Neurexins are presynaptic cell-adhesion molecules essential for synaptic function that are expressed in thousands of alternatively spliced isoforms. Recent studies suggested that alternative splicing at splice site 4 (SS4) of Nrxn1 is tightly regulated ...
Kif Liakath-Ali +3 more
doaj +1 more source
Folia Morphologica, 2022 BACKGROUND: Neuronostatin, a newly identified peptide, is accepted as an anorexigenic peptide since it suppresses food intake when given intracerebroventricularly.
S. Serter Kocoglu +3 more
doaj +1 more source
Brain Sciences, 2022 Brain control by locus coeruleus (LC) neurons involves afferent glutamate (Glu) inputs. In newborns, LC Glu receptors and responses may be sparse due to immaturity of the brain circuits providing such input.
Bijal Rawal, Klaus Ballanyi
doaj +1 more source
Neurobiology of Disease, 1994 Kainate-activated Co2+uptake, a histochemical method that identifies cells bearing Ca2+-permeable AMPA/kainate receptors, labels approximately 15% of murine cortical neurones in cell culture.
Dorothy M. Turetsky +5 more
doaj +1 more source
7-nitroindazole, a selective neuronal nitric oxide synthase inhibitore in vivo, prevents kainate-induced intrahippocampal neurotoxicity [PDF]
Archives of Biological Sciences, 2005 We investigated the effects of 7-nitroindazole (7-NI), a selective neuronal nitric oxide synthase inhibitor in vivo, on nitrite concentration after kainic acid injection unilaterally into the CA3 region of the rat hippocampus. The accumulation of nitrite,
Radenović Lidija Lj. +2 more
doaj +1 more source
Nimesulide limits kainate-induced oxidative damage in the rat hippocampus [PDF]
, 2000 Kainate induces a marked expression of cyclooxygenase-2 after its systemic administration. Because cyclooxygenase-2 activity is associated to the production of reactive oxygen species, we investigated the effects of nimesulide, a selective cyclooxygenase-
Ajamieh, Hussam +4 more
core +1 more source
Reduced Interhemispheric Coherence after Cerebellar Vermis Output Perturbation
Brain Sciences, 2020 Motor coordination and motor learning are well-known roles of the cerebellum. Recent evidence also supports the contribution of the cerebellum to the oscillatory activity of brain networks involved in a wide range of disorders.
Elena Laura Georgescu Margarint +7 more
doaj +1 more source
Molecular Physiology of Kainate Receptors [PDF]
Physiological Reviews, 2001 A decade ago, our understanding of the molecular properties of kainate receptors and their involvement in synaptic physiology was essentially null. A plethora of recent studies has altered this situation profoundly such that kainate receptors are now regarded as key players in the modulation of transmitter release, as important mediators of the ...
Juan Lerma +3 more
openalex +4 more sources
Role of brain glycogen in the response to hypoxia and in susceptibility to epilepsy
Frontiers in Cellular Neuroscience, 2015 Although glycogen is the only carbohydrate reserve of the brain, its overall contribution to brain functions remains unclear. It has been proposed that glycogen participates in the preservation of such functions during hypoxia.
Juan Carlos eLópez Ramos +5 more
doaj +1 more source
Kainate Receptors: Role in Epilepsy
Frontiers in Molecular Neuroscience, 2018 Kainate (KA) is a potent neurotoxin that has been widely used experimentally to induce acute brain seizures and, after repetitive treatments, as a chronic model of temporal lobe epilepsy (TLE), with similar features to those observed in human patients ...
Rafael Falcón-Moya1 +2 more
semanticscholar +1 more source