Results 31 to 40 of about 24,046 (180)
Involvement of kainate glutamate receptors in the modulation of neuronal transmission in brain areas involved in migraine pathophysiology [PDF]
, 2009 Migraine pathophysiology is thought to involve activation of the trigeminal fibres which innervate dural structures. The nociceptive inflow from the meninges is relayed to the trigeminocervical complex (TCC), before ascending to higher brain areas ...
Andreou, A.
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Frontiers in Neurology, 2011 The P13 potential is the rodent equivalent of the P50 potential, which is an evoked response recorded at the vertex (Vx) 50 msec following an auditory stimulus in humans.
Christen eSimon +4 more
doaj +1 more source
Anterior cingulate cortex neuron subtypes differentially regulate seizures
Epilepsia, EarlyView.Abstract Objective This study aimed to investigate the regulatory roles of distinct neuronal subtypes within the anterior cingulate cortex (ACC) in acute seizures and to identify cell type‐specific mechanisms underlying seizure modulation in this region. Methods Acute seizure models were established in mice via pentylenetetrazol injection.
Ziqian Yan +12 more
wiley +1 more source
Kainate receptor function in rodent subcortical visual processing. [PDF]
, 2007 Glutamate is found throughout the central nervous system and has been shown to be an important excitatory neurotransmitter in the visual system. There are two subdivisions of receptor on which this ubiquitous neurotransmitter acts, metabotropic (mGluR ...
Pothecary, C.A.
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A Transmembrane Accessory Subunit that Modulates Kainate-Type Glutamate Receptors [PDF]
, 2009 SummaryGlutamate receptors play major roles in excitatory transmission in the vertebrate brain. Among ionotropic glutamate receptors (AMPA, kainate, NMDA), AMPA receptors mediate fast synaptic transmission and require TARP auxiliary subunits.
Burlingame, Alma L. +21 more
core +1 more source
WONOEP appraisal: Biomarkers and treatment strategies beyond the synapse
Epilepsia, EarlyView.Abstract Epilepsy is a heterogeneous neurological disorder affecting more than 70 million people worldwide, posing significant challenges for clinicians due to its complex etiology, diverse manifestations, variable treatment responses, and the inability to predict seizures or disease onset reliably.
Mirte Scheper +11 more
wiley +1 more source
Frontiers in Cell and Developmental Biology, 2023 Ionotropic glutamate receptors (iGluRs) mediate the majority of excitatory neurotransmission and are implicated in various neurological disorders. In this review, we discuss the role of the two fastest iGluRs subtypes, namely, α-amino-3-hydroxy-5-methyl ...
Marina N. Vukolova +5 more
doaj +1 more source
Status epilepticus in adults: From etiology to treatment response
Epilepsia, EarlyView.Abstract This study explored the association between etiology of status epilepticus (SE) and treatment responsiveness. Consecutive episodes of nonhypoxic SE in patients ≥14 years old were included. Etiology was classified into acute, remote, progressive, defined electroclinical syndromes, and unknown.
Simona Lattanzi +5 more
wiley +1 more source
Epilepsia Open, 2019 Summary Objective Temporal lobe epilepsy (TLE) is often associated with memory deficits. Reactivation of memory traces in the hippocampus occurs during sharp‐wave ripples (SWRs; 140‐250 Hz).
Ivan Marchionni +3 more
doaj +1 more source
Frontiers in Neurology, 2018 Various etiological factors, such as head injury, chemical intoxication, tumors, and gene mutation, can induce epileptogenesis. In animal models, status epilepticus (SE) triggers epileptogenesis.
Shaunik Sharma +4 more
doaj +1 more source