Changes of cochlear function during cochlear fluids manipulations [PDF]
Spatial origins of compound action potential responses to varying stimulation rates, frequencies, and levels were investigated. A technique to measure the regions in the cochlea generating each response in which a neurotoxic drug (kainic acid) is slowly ...
Donovan, Kathryn Marie
core +1 more source
PurposeImbalance of inhibitory GABAergic neurotransmission has been proposed to play a role in the pathogenesis of temporal lobe epilepsy (TLE). This study aimed to investigate whether [(18)F]-flumazenil ([(18)F]-FMZ) PET could be used to non-invasively ...
Lucy Vivash+11 more
doaj +1 more source
Anti-epileptic properties of terpineol extracted from Myristica fragrans Houtt. essential oil in the epileptic rat model. [PDF]
Epilepsy is the manifestation of the disease due to overstimulation of the brain. The common signs of this disease are chronic, episodic and recurrent seizures.
Abdul Rahman, Mohd Amir Asyraf+3 more
core
Oscillatory Cortical Activity in an Animal Model of Dystonia Caused by Cerebellar Dysfunction
The synchronization of neuronal activity in the sensorimotor cortices is crucial for motor control and learning. This synchrony can be modulated by upstream activity in the cerebello-cortical network.
Elena Laura Georgescu+9 more
doaj +1 more source
Kainic Acid Induced Seizures and the GABA System in the Substantia Nigra [PDF]
Author Institution: Department of Biological Sciences, Bowling Green State UniversityGamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter implicated in the control of generalized seizures induced by various convulsants.
Meserve, Lee A., Shaffer, Lillian M.
core
Dentate granule cells are essential for kainic acid-induced wet dog shakes but not for seizures [PDF]
Laura M. Grimes+5 more
openalex +1 more source
Outer hair cells stir cochlear fluids
We hypothesized that active outer hair cells drive cochlear fluid circulation. The hypothesis was tested by delivering the neurotoxin, kainic acid, to the intact round window of young gerbil cochleae while monitoring auditory responses in the cochlear ...
Choongheon Lee+5 more
doaj +1 more source
Kainic acid on neostriatal neurons intracellularly recorded in vitro: electrophysiological evidence for differential neuronal sensitivity [PDF]
Paolo Calabresi+3 more
openalex +1 more source
Excitotoxicity is the pivotal mechanism of neuronal death. Prostaglandins (PGs) produced during excitotoxicity play important roles in neurodegenerative conditions.
Kensuke Iwasa+4 more
doaj
Kainic acid lesions of the dorsal nucleus of the lateral lemniscus: effects on binaural evoked responses in rat auditory cortex [PDF]
S.Lynn Glenn, JB Kelly
openalex +1 more source