Results 151 to 160 of about 15,680 (217)

Cleavage of the TrkB-FL receptor during epileptogenesis: insights from a kainic acid-induced model of epilepsy and human samples.

Pharmacol Res
Ribeiro-Rodrigues L, Fonseca-Gomes J, Paulo SL, Viais R, Ribeiro FF, Miranda-Lourenço C, Mouro FM, Belo RF, Ferreira CB, Tanqueiro SR, Ferreira-Manso M, Umemori J, Castrén E, Paiva VH, Sebastião AM, Aronica E, Campos AR, Bentes C, Xapelli S, Diógenes MJ.   +19 more
europepmc   +1 more source

Effects of minocycline on dendrites, dendritic spines, and microglia in immature mouse brains after kainic acid-induced status epilepticus. [PDF]

CNS Neurosci Ther
Yang X, Li T, Liu J, Sun H, Cheng L, Song X, Han Z, Luo H, Han W, Xie L, Jiang L.   +10 more
europepmc   +1 more source

Structure and Syntheses of Kainic Acid

Journal of Synthetic Organic Chemistry, Japan, 1957
openaire   +2 more sources

Anti-epileptic and Neuroprotective Effects of Ultra-low Dose NADPH Oxidase Inhibitor Dextromethorphan on Kainic Acid-induced Chronic Temporal Lobe Epilepsy in Rats. [PDF]

Neurosci Bull
Yang JJ, Liu YX, Wang YF, Ge BY, Wang Y, Wang QS, Li S, Zhang JJ, Jin LL, Hong JS, Yin SM, Zhao J.   +11 more
europepmc   +1 more source

Kv7 channel activation reduces brain endothelial cell permeability and prevents kainic acid-induced blood-brain barrier damage.

Am J Physiol Cell Physiol
Celentano C, Carotenuto L, Miceli F, Carleo G, Corrado B, Baroli G, Iervolino S, Vecchione R, Taglialatela M, Barrese V.   +9 more
europepmc   +1 more source

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Kainic acid derivatives with anticonvulsant activity

Neuroscience Letters, 1984
beta-Kainic acid, and the glycine and amino-methylphosphonate derivatives of alpha- and beta-kainic acid, have been injected intracerebroventricularly in DBA/2 mice, that show sound-induced seizure responses. An anticonvulsant effect is observed with marked protection against the tonic and clonic phases of the seizure response.
J F Collins, Giovambattista De Sarro, B S Meldrum   +2 more
exaly   +3 more sources

Scalable Biosynthesis of the Seaweed Neurochemical, Kainic Acid [PDF]

Angewandte Chemie - International Edition, 2019
Kainic acid, the flagship member of the kainoid family of natural neurochemicals, is a widely used neuropharmacological agent that helped unravel the key role of ionotropic glutamate receptors, including the kainate receptor, in the central nervous ...
Jonathan R Chekan, Shaun M K Mckinnie, Shane G Poplawski   +2 more
exaly   +2 more sources

The kainic acid model of temporal lobe epilepsy

Neuroscience and Biobehavioral Reviews, 2013
The kainic acid model of temporal lobe epilepsy has greatly contributed to the understanding of the molecular, cellular and pharmacological mechanisms underlying epileptogenesis and ictogenesis.
Maxime Lévesque, Massimo Avoli
exaly   +2 more sources

On the Specificity of Kainic Acid

Science, 1979
The specificity of the neurotoxic agent, kainic acid, for destroying cell bodies while sparing terminals and fibers of passage was examined by infusing this agent into the axons of the dorsal noradrenergic bundle and measuring the degree of depletion of noradrenaline concentrations and the reduction in noradrenaline uptake in cortex and hippocampus ...
S T, Mason, H C, Fibiger
openaire   +2 more sources