Results 181 to 190 of about 15,680 (217)

An enantioconvergent route to (−)-kainic acid

Tetrahedron Letters, 1997
Abstract A new stereocontrolled route to (−)-kainic acid, the representative of the kainoid amino acids and exhibiting insecticidal, anthelmintic and neuroexcitatory properties, has been devised in an enantioconvergent way using either (+)- or (−)-ketodicyclopentadiene as the starting material by employing a concurrent retro-Diels-Alder reaction and ...
Yoshihisa Nakada, Tsutomu Sugahara, Kunio Ogasawara   +2 more
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Kainic acid and the glutamate receptor

Neuroscience Letters, 1978
Abstract The excitatory effects of microelectrophoretically administered kainic (KAIN) and glutamic (GLUT) acids have been compared on central neurones of the rat in the presence of antagonists of amino acid-induced excitations. Antagonism by both D-α-amino adipic acid (DAA) and glutamic acid diethyl ester (GDEE) of the effects of glutamic acid but ...
Hall, J., Hicks, T., Mclennan, H.
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Iontophoresis of kainic acid

Neurochemical Research, 1981
J A, McCaughran, E G, McGeer
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The mechanism of kainic acid neurotoxicity

Nature, 1984
J W, Ferkany, R, Zaczek, J T, Coyle
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Neuronal mapping with kainic acid

Trends in Neurosciences, 1978
Abstract Kainic acid, found naturally-occurring in sea-weed, is a substance which is structurally-related to the putative neurotransmitter, glutamate. Kainic acid has now entered the neuroscientists armoury of equipment as a potent and selective neurotoxin which will cause the fast degeneration of neurones with cell bodies in the area of injection ...
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Kainic Acid: The Neurotoxic Breakthrough

CRC Critical Reviews in Toxicology, 1982
Patrick L. McGeer, E. G. McGeer, John W. Olney   +2 more
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Biosynthesis of kainic acid uncovered

C&EN Global Enterprise, 2019
For centuries, certain red seaweeds were used to treat intestinal worm infections in Japan. And neuroscientists have used the active ingredient from those plants—a molecule known as kainic acid—to ...
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Strain differences and kainic acid neurotoxicity

Brain Research, 1979
P R, Sanberg, M, Pisa, E G, McGeer
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Synthesis of (-)-Kainic Acid

Synfacts, 2007
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Kainic acid neurotoxicity in the mouse cerebellum

Brain Research, 1980
K L, Lovell, M Z, Jones
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